3 metabolic equivalents (METS)) and the number of steps overlapped with controls, but CF patients had less moderate PA (>4.8 METS). Moderate PA was related to peak oxygen uptake and quadriceps force. Skeletal muscle weakness and exercise intolerance are prevalent in cystic fibrosis. Physical inactivity is a factor significantly contributing to exercise tolerance and skeletal muscle force in adults with cystic fibrosis, but these impairments are in excess to that expected from physical inactivity only.">

Skeletal muscle weakness, exercise tolerance and physical activity in adults with cystic fibrosis

Troosters T., Langer D., Vrijsen B., Segers J., Wouters K., Janssens W., Gosselink R., Decramer M., Dupont L.

Source: Eur Respir J 2009; 33: 99-106
Journal Issue: January

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Troosters T., Langer D., Vrijsen B., Segers J., Wouters K., Janssens W., Gosselink R., Decramer M., Dupont L.. Skeletal muscle weakness, exercise tolerance and physical activity in adults with cystic fibrosis. Eur Respir J 2009; 33: 99-106

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Managing skeletal muscle dysfunction in COPD
Source: Eur Respir Mon 2013; 59: 164-173
Year: 2013


Skeletal muscle adiposity is associated with physical activity, exercise capacity and fibre shift in COPD
Source: Eur Respir J 2014; 44: 1188-1198
Year: 2014



Association of pulmonary dysfunction with physical inactivity and loss of muscle mass in elderly COPD patients
Source: Annual Congress 2013 –Respiratory and cardiovascular abnormalities in COPD: the role of exercise, nutritional status and inflammation
Year: 2013

Skeletal muscle function and structure in patients with non-cystic fibrosis bronchiectasis
Source: International Congress 2016 – Best abstracts in pulmonary rehabilitation and chronic care
Year: 2016

Quadriceps muscle contractility and fatigability in cystic fibrosis (CF) patients
Source: International Congress 2015 – Clinical exercise physiology in health and disease
Year: 2015

Respiratory muscle endurance in cystic fibrosis: impact on exercise capacity and dyspnea
Source: Eur Respir J 2005; 26: Suppl. 49, 178s
Year: 2005

The impact of an acute exacerbation on physical activity and skeletal muscle force in patients with cystic fibrosis
Source: Annual Congress 2009 - Physiotherapy aspects in cystic fibrosis and functional assessment
Year: 2009

Skeletal muscle oxidative capacity is an independent predictor of physical activity in smokers with and without COPD
Source: International Congress 2015 – Clinical physiology: mechanisms of symptoms and exercise limitations in health and disease
Year: 2015


Lung function, functional capacity, energy cost, and nutritional status in cystic fibrosis with and without inspiratory muscle weakness
Source: International Congress 2019 – New views on testing and training of respiratory muscles
Year: 2019

Correlation of physical fitness with peripheral muscle strength, physical activity levels and lung function in patients with cystic fibrosis
Source: International Congress 2018 – Cystic fibrosis in adults: current research
Year: 2018


Skeletal muscle metabolism in active cystic fibrosis (CF) patients with light/moderate pulmonary dysfunction
Source: International Congress 2015 – Clinical exercise physiology in health and disease
Year: 2015

Features of skeletal muscle dysfunction in COPD patients with obesity
Source: International Congress 2015 – COPD: chronic disease and comorbidities
Year: 2015


No effect of low-intensity endurance exercise on muscle necrosis in the diaphragm of mdx mice
Source: International Congress 2014 – Pathophysiological mechanisms at different scales
Year: 2014


Physical activity is independently related to aerobic capacity in cystic fibrosis
Source: Eur Respir J 2006 Oct 01;28(4):734-739
Year: 2006



Resistance versus endurance training in patients with COPD and peripheral muscle weakness
Source: Eur Respir J 2002; 19: 1072-1078
Year: 2002



Assessment of Lumacaftor/Ivacaftor therapy on physical activity and exercise tolerance in adults with cystic fibrosis
Source: Virtual Congress 2020 – Clinical monitoring and new therapies for cystic fibrosis
Year: 2020


Effects of Inspiratory muscle training on respiratory muscle strength, physical fitness and dyspnea in obese women.
Source: International Congress 2019 – Assessment and training of respiratory muscles
Year: 2019

Intensity of daily activity may affect exercise capacity and peripheral muscle function in adults with cystic fibrosis
Source: Annual Congress 2013 –Cystic fibrosis: physiotherapy, exercise and lung function in adults and children
Year: 2013


Effects of inspiratory muscle training on functional capacity and muscle strength in patients with mild cystic fibrosis
Source: Annual Congress 2010 - Mucous clearance and treatment modalities in respiratory physiotherapy
Year: 2010

Prevalence and importance of skeletal muscle weakness in cystic fibrosis
Source: Eur Respir J 2006; 28: Suppl. 50, 629s
Year: 2006