GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Selective inhibition of COX-2 by celecoxib exerts negative effects on endothelial progenitor cell proliferation and stimulates apoptosis in vitro Source: Eur Respir J 2005; 26: Suppl. 49, 368s Year: 2005
The PDE4-inhibitors roflumilast and rolipram modulate fibroblast collagen-gel contraction and chemotaxis mediated by autocrine PGE2 synthesis induced by TGF-β1 Source: Eur Respir J 2005; 26: Suppl. 49, 214s Year: 2005
Effect of PDE4 inhibitors on MAPK activation and IL-8 production on A549 cells following the induction of oxidative stress Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
The inhibitory mechanism of transferring iNOS gene to PASMCs on hypoxia induced proliferation Source: Eur Respir J 2002; 20: Suppl. 38, 88s Year: 2002
COX-1 driven biosynthesis of PGD2 during activation of human mast cells prevents formation of other prostanoids Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes Year: 2020
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescence Source: Annual Congress 2011 - Epithelial cells: role in health and disease Year: 2011
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004
Dexamethasone potently induces human basophil apoptosis Source: Eur Respir J 2002; 20: Suppl. 38, 29s Year: 2002
The angiogenic integrin a9b1 promotes cell migration through Src-dependent activation of nitric oxide synthesis Source: Annual Congress 2009 - What is new in molecular pathology and functional genomics of neoplastic and non-neoplastic lung disease? Year: 2009
Exogenous HSP60 stimulates airway smooth muscle cell remodeling via MAPK p38 pathway Source: Virtual Congress 2020 – Monitoring of inflammation in remodelling Year: 2020
ET-1 regulates pathological cell proliferation by ERK1/2 in a state of chronic inflammation Source: Annual Congress 2010 - Novel cellular mechanisms in lung disease Year: 2010
Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 29s Year: 2004
Bradykinin-induced fibroblast proliferation and myofibroblast differentiation via B2 receptor pathway Source: Eur Respir J 2005; 26: Suppl. 49, 342s Year: 2005
Thrombin induces epithelial-mesenchymal transition via PAR1, PKC and ERK1/2 pathways in A549 cells Source: Annual Congress 2012 - Diffuse parenchymal lung disease pathogenesis, biomarkers, therapy and new entities Year: 2012
Hypoxia-dependent Fhl-1 regulation leads to proproliferative effects in PASMC Source: Annual Congress 2008 - Pathophysiology of pulmonary hypertension Year: 2008
Angiopoietin-1 inhibits endothelial permeability and neutrophil adherence induced by H2 O2 or thrombin Source: Eur Respir J 2002; 20: Suppl. 38, 228s Year: 2002