Long-term effect of alpha-1-antitrypsin augmentation therapy on the decline of FEV1 in deficient patients

I. Schouten (Leiden, Netherlands), M. Kasteleyn (Leiden, Netherlands), R. Bals (Homburg/Saar, Germany), A. Turner (Birmingham, United Kingdom), I. Ferrarotti (Pavia, Italy), A. Corsico (Pavia, Italy), B. Lara Gallego (Coventry, United Kingdom), M. Miravitlles (Barcelona, Spain), R. Stockley (Birmingham, United Kingdom), J. Stolk (Leiden, Netherlands)

Source: Virtual Congress 2021 – Treatments for airway diseases
Session: Treatments for airway diseases
Session type: E-poster
Number: 1833

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
I. Schouten (Leiden, Netherlands), M. Kasteleyn (Leiden, Netherlands), R. Bals (Homburg/Saar, Germany), A. Turner (Birmingham, United Kingdom), I. Ferrarotti (Pavia, Italy), A. Corsico (Pavia, Italy), B. Lara Gallego (Coventry, United Kingdom), M. Miravitlles (Barcelona, Spain), R. Stockley (Birmingham, United Kingdom), J. Stolk (Leiden, Netherlands). Long-term effect of alpha-1-antitrypsin augmentation therapy on the decline of FEV1 in deficient patients. 1833

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Long-term effect of a1-antitrypsin augmentation therapy on the decline of FEV1 in deficient patients: an analysis of the AIR database
Source: ERJ Open Res, 7 (3) 00194-2021; 10.1183/23120541.00194-2021
Year: 2021



Annual FEV1% variation before and after augmentation therapy in severe alpha-1-antitrypsin deficiency
Source: International Congress 2019 – COPD treatment: clinical trials, cohorts and inhaler device studies
Year: 2019


Effect of intravenous alpha-1-antitrypsin augmentation therapy on proteinase-3-generated AaVal541 in deficient patients
Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science
Year: 2021


Effect of augmentation therapy on immune function of patients with severe Alpha1-antitrypsin deficiency
Source: Annual Congress 2012 - COPD treatments: efficacy and safety
Year: 2012


Efficacy of augmentation therapy for emphysema associated with alpha1-antitrypsin deficiency: enough is enough
Source: Eur Respir J 2016; 47: 35-38
Year: 2016


FVC decline in patients with SSc-ILD by use of anti-acid therapy
Source: Virtual Congress 2020 – Addressing unresolved questions in rare diffuse parenchymal lung diseases: interdisciplinary research is the key
Year: 2020


Reducing the decline of FEV1 after a 4-year therapy with montelukast in patients with bronchial asthma
Source: Annual Congress 2008 - Recent advances in the pathogenesis and treatment of asthma and COPD
Year: 2008


Prevalence of alpha1-antitrypsin deficiency and its influence on lung function decline in patients with severe asthma
Source: Virtual Congress 2020 – Advances in asthma treatment
Year: 2020


Early ICS treatment in subjects with a rapid decline in lung function
Source: Eur Respir J 2001; 18: Suppl. 33, 348s
Year: 2001

Impact of alpha 1-antitrypsin deficiency and prior augmentation therapy on patients' survival after lung transplantation
Source: Eur Respir J, 50 (3) 1700962; 10.1183/13993003.00962-2017
Year: 2017



Does an acute FEV1 response predict long-term improvements with bronchodilators in patients with COPD?
Source: Eur Respir J 2001; 18: Suppl. 33, 486s
Year: 2001

A rejuvenation effect of the antifibrotic therapy correlates with lung function improvement in IPF patients
Source: Virtual Congress 2021 – Novel insights into the pathogenesis of chronic lung diseases
Year: 2021


Comparison of outcomes in augmentation naïve and augmented patients with alpha-1 antitrypsin deficiency related lung disease.
Source: International Congress 2019 – COPD clinical studies: bronchodilators, corticosteroids and more
Year: 2019


Long-term effect of sildenafil on exercise capacity in COPD patients
Source: Eur Respir J 2007; 30: Suppl. 51, 608s
Year: 2007

The effect of augmentation therapy on systemic and pulmonary inflammation markers in α1-antitrypsin deficiency patients
Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases
Year: 2010

Does atorvastatin have effect on lung function and morbidity as add-on therapy in asthmatic patients?
Source: Annual Congress 2007 - New drugs for asthma
Year: 2007




Rates of change in FEV1 and DLCO as potential indicators for mTOR inhibitor therapy in premenopausal lymphangioleiomyomatosis patients
Source: Eur Respir J, 51 (4) 1702258; 10.1183/13993003.02258-2017
Year: 2018



Oral corticosteroid treatment reduces serum chitotriosidase activity in patients with COPD
Source: Annual Congress 2010 - COPD: treatment and monitoring
Year: 2010

Long-term experience in the treatment of alpha 1-antitrypsin deficiency: 25 years of augmentation therapy
Source: Eur Respir Rev 2015; 24: 46-51
Year: 2015



Early health status improvements decline after LVRS despite persistent reduction in lung volume
Source: Eur Respir J 2002; 20: Suppl. 38, 607s
Year: 2002