Indacaterol acetate, glycopyrronium bromide, and mometasone furoate: effect on human airway inflammation

P. Rogliani (Roma (RM), Italy), B. Ritondo (Roma (RM), Italy), F. Facciolo (Roma (RM), Italy), I. Nikolaev (Basel (CH), Switzerland), L. Calzetta (Parma (PR), Italy)

Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science
Session: Airway pharmacology: translational and basic science
Session type: E-poster
Number: 546

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
P. Rogliani (Roma (RM), Italy), B. Ritondo (Roma (RM), Italy), F. Facciolo (Roma (RM), Italy), I. Nikolaev (Basel (CH), Switzerland), L. Calzetta (Parma (PR), Italy). Indacaterol acetate, glycopyrronium bromide, and mometasone furoate: effect on human airway inflammation. 546

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Indacaterol acetate, glycopyrronium bromide, and mometasone furoate: effect on neuronal inflammation and acetylcholine release
Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science
Year: 2021


Budesonide is better retained in airway tissue than fluticasone propionate and mometasone furoate due to the formation of lipophilic, slowly hydrolyzed budesonide esters
Source: Eur Respir J 2003; 22: Suppl. 45, 281s
Year: 2003

Variable lipophilicity of budesonide: Comparison with fluticasone propionate, mometasone furoate, and ciclesonide
Source: Eur Respir J 2003; 22: Suppl. 45, 33s
Year: 2003

Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma
Source: Eur Respir J 2014; 43: 773-782
Year: 2014



Mometasone furoate is a less specific glucocorticoid than fluticasone propionate
Source: Eur Respir J 2002; 20: 1386-1392
Year: 2002



Role of budesonide, formoterol fumarate and aclidinium bromide in the inflammaging of airway epithelial cells
Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects
Year: 2017

Extrafine glycopyrronium bromide (GB) in addition to extrafine beclomethasone dipropionate/formoterol fumarate (BDP/FF) in uncontrolled asthmatic patients
Source: International Congress 2018 – Innovative therapies in asthma and COPD
Year: 2018



Pharmacokinetics of indacaterol, glycopyrronium and mometasone furoate following once daily inhalation as a fixed-dose combination in healthy subjects
Source: International Congress 2019 – Clinical studies of asthma treatments
Year: 2019


Clinical efficacy of once-daily mometasone furoate in children with persistent asthma switched from treatment with fluticasone propionate
Source: Annual Congress 2011 - Airways disease comorbidities and general aspects
Year: 2011

Comparison of inhaled ciclesonide, fluticasone propinate and fluticasone propionate + salmeterol in maintaining asthma control
Source: Annual Congress 2009 - Drug treatment of childhood asthma: the controversies and the issues
Year: 2009

Fluticasone propionate is as potent but more receptor-selective than mometasone furoate
Source: Eur Respir J 2001; 18: Suppl. 33, 95s
Year: 2001

A comparison of fluticasone propionate (FP) and mometasone furoate (MF) nasal spray in the treatment of nasal polyposis associated with asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 314s
Year: 2006

Mometasone furoate delivered via Breezhaler and Twisthaler in patients with asthma
Source: International Congress 2019 – Asthma: outcomes of clinical trials and cohorts
Year: 2019


Efficacy of the novel inhaled corticosteroid, fluticasone furoate (FF)/long-acting beta2-agonist, vilanterol (VI) combination in reducing COPD exacerbations
Source: Annual Congress 2012 - Trials in COPD: novel treatments and insights
Year: 2012

Higher cellular retention and activity after pulse exposure by budesonide (BUD) than fluticasone propionate (FP) and mometasone furoate (MF)
Source: Eur Respir J 2001; 18: Suppl. 33, 158s
Year: 2001

Administration of mometasone furoate once daily in the evening is as effective as mometasone furoate administered twice daily in improving lung function in patients with mild to moderate persistent asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 33s
Year: 2003

Once-daily versus twice-daily administration of mometasone furoate dry powder inhaler (MF-DPI) improves lung function in children with asthma previously maintained on inhaled corticosteroids (ICS)
Source: Eur Respir J 2004; 24: Suppl. 48, 164s
Year: 2004

Seasonality of asthma exacerbations: efficacy of fluticasone furoate/vilanterol 100/25µg (FF/VI) vs fluticasone furoate 100µg (FF) alone
Source: International Congress 2017 – Asthma management
Year: 2017


Budesonide is retained in the airways longer than mometasone furoate due to the reversible formation of lipophilic budesonide fatty acid esters - significance for asthma therapy
Source: Eur Respir J 2002; 20: Suppl. 38, 53s
Year: 2002

Scientific rationale for inhaled combination therapy with long-acting β2-agonists and corticosteroids
Source: Eur Respir J 2002; 19: 182-191
Year: 2002