Source: Virtual Congress 2020 – Translational therapeutic advances
Disease area: Interstitial lung diseases



Rating:

Share or cite this content

Citations should be made in the following way:
J. Zhang (Miami, United States of America), R. Cui (Miami, United States of America), T. Runxia (Miami, United States of America), R. Cai (Miami, United States of America), M. Mirsaeidi (Miami, United States of America), A. Schally (Miami, United States of America), R. Jackson (Miami, United States of America). Growth hormone releasing hormone-receptor antagonist MIA-602 modulates lung inflammation, cellular signal transduction, and promotes apoptosis of mouse lung fibroblasts. 3353

Member's Comments

No comment yet.

Related content which might interest you: Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010 P2X7 receptor regulates cell survival, inflammation processes and proliferation of lung carcinoma cells Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease Year: 2019 Bile acid receptor accelerates to the lung cancer process induced by lung fibroblast-tumor cells interaction, with high activation of phosphorylated STAT3 and alteration of cytokine secretion Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench Year: 2017 SiRNA mediated growth factor receptors inhibition in A549 cell model of lung cancer gene therapy: insulin-like growth factor-I receptor (IGF-R1) blockade produces changes that potentially induce anti-tumor immunity Source: Annual Congress 2008 - Biology in thoracic tumours Year: 2008 Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004 Growth hormone-releasing hormone receptor antagonist MIA-602 modulates mouse lung inflammation and fibrosis due to bleomycin Source: International Congress 2018 – New insights in the signalling pathways that underlie IPF pathophysiology Year: 2018 Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009 Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006 The epidermal growth factor receptor mediates allergic airway remodelling in the rat Source: Eur Respir J 2008; 32: 1213-1223 Year: 2008 Growth hormone releasing hormone receptor (GHRH-R) antagonist MIA-602 modulates fibrosis and gene expression in lungs of bleomycin-treated mice Source: International Congress 2019 – Translational aspects of idiopathic interstitial pneumonia Year: 2019 Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004 Analysis of signal transduction pathways involved in proteinase activated receptor-2 (PAR-2) stimulated mucus secretion in human tracheal gland cell culture Source: Annual Congress 2008 - Airway cell biology Year: 2008 Effects of Liver X receptor agonist treatment on signal transduction pathways in acute lung inflammation Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis Year: 2010 Inhibition of insulin-like growth factor type I (IGF-I) gene in A549 human lung cancer cell line enhances cell apoptosis and causes phenotype changes relevant to increased tumor susceptibility to immune system Source: Eur Respir J 2007; 30: Suppl. 51, 715s Year: 2007 NTHi-promoted proliferation of K-ras-induced early lung cancer lesions is fully dependent on Toll-like receptor signaling Source: International Congress 2017 – Basic research in lung cancer: a scientific potpourri from genetic alterations to immune cells Year: 2017 Muscarinic receptors mediate up-regulation of endothelin-1 expression in human lung fibroblasts Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010 Interleukin-8 stimulates human airway epithelial cell proliferation through EGFR transactivation Source: Eur Respir J 2003; 22: Suppl. 45, 561s Year: 2003 Circulating fibrocytes depletion results in reduced lung tumor growth and metastasis by modulating macrophage phenotype, angiogenesis and endothelin system Source: ERS Lung Science Conference 2017 Year: 2017 Composition of the cellular matrix, nutrition, and hypoxia modulate the secretion and activation of collagenases and their inhibitors in human lung cells Source: Eur Respir J 2001; 18: Suppl. 33, 244s Year: 2001