Prevalence of alpha1-antitrypsin deficiency and its influence on lung function decline in patients with severe asthma

A. Vianello (Padua (PD), Italy), G. Guarnieri (Padua (PD), Italy), B. Molena (Padua (PD), Italy), N. Malacchini (Padua (PD), Italy), F. Chieco Bianchi (Padua (PD), Italy), I. Ferrarotti (Pavia (PV), Italy), M. Caminati (Verona (VR), Italy), G. Senna (Verona (VR), Italy)

Source: Virtual Congress 2020 – Advances in asthma treatment
Session: Advances in asthma treatment
Session type: E-poster session
Number: 2624
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Vianello (Padua (PD), Italy), G. Guarnieri (Padua (PD), Italy), B. Molena (Padua (PD), Italy), N. Malacchini (Padua (PD), Italy), F. Chieco Bianchi (Padua (PD), Italy), I. Ferrarotti (Pavia (PV), Italy), M. Caminati (Verona (VR), Italy), G. Senna (Verona (VR), Italy). Prevalence of alpha1-antitrypsin deficiency and its influence on lung function decline in patients with severe asthma. 2624

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Lung function decline in relation to alpha-1-antitrypsin phenotypes in severe asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 479s
Year: 2003

Rate of progression of lung function impairment in α1-antitrypsin deficiency
Source: Eur Respir J 2009; 33: 1338-1344
Year: 2009



Predictors of accelerated decline in lung function in adult-onset asthma
Source: Eur Respir J, 51 (2) 1701785; 10.1183/13993003.01785-2017
Year: 2018



Screening for α1-Pi deficiency in patients with lung diseases
Source: Eur Respir J 2002; 20: 319-324
Year: 2002



Exacerbations and duration of smoking abstinence are associated with the annual decline in lung function in individuals with PiZZ alpha-1-antitrypsin deficiency
Source: International Congress 2017 – Current challenges in COPD evaluation
Year: 2017

Dupilumab improves lung function in patients with uncontrolled, moderate-to-severe asthma
Source: ERJ Open Res, 6 (1) 00204-2019; 10.1183/23120541.00204-2019
Year: 2020



Exploring the relationship between alpha-1-antitrypsin deficiency and persistent airflow limitation in severe asthma.
Source: International Congress 2017 – Rare and common genetic variants of common and rare airway diseases
Year: 2017


Influence of obesity on pulmonary function (PF) in severe asthmatic children
Source: Annual Congress 2011 - Coping and lifestyle in childhood asthma
Year: 2011

Intermediate and severe α1-antitrypsin deficiency: influence on plasma α1-antitrypsin, FEV1 and risk of COPD. Three meta-anlyses
Source: Eur Respir J 2002; 20: Suppl. 38, 513s
Year: 2002

Iron deficiency as a novel biomarker of functional impairment in patients with chronic obstructive pulmonary disease (COPD)
Source: Annual Congress 2011 - Physiological basis of respiratory disease
Year: 2011

Cardio-vascular co-morbidities and severity of lung function impairment in a COPD cohort
Source: Eur Respir J 2006; 28: Suppl. 50, 160s
Year: 2006

Estimating lung function decline and the effect of smoking in COPD patients
Source: Eur Respir J 2002; 20: Suppl. 38, 578s
Year: 2002

Accelerated decline in lung function in adults with a history of remitted childhood asthma
Source: Eur Respir J, 59 (1) 2100305; 10.1183/13993003.00305-2021
Year: 2022



Dupilumab improves lung function and reduces severe exacerbations in uncontrolled persistent asthma patients with high and low reversibility
Source: International Congress 2017 – Evolution or revolution in the treatment of asthma and allergies
Year: 2017


Influence of β2-adrenoceptor genotype on risk of asthma worsening using fluctuation analysis of lung function
Source: Eur Respir J 2007; 30: Suppl. 51, 447s
Year: 2007

Association of wheeze with lung function decline in children with sickle cell disease
Source: Eur Respir J, 50 (5) 1602433; 10.1183/13993003.02433-2016
Year: 2017



Severe exacerbations predict excess lung function decline in asthma
Source: Eur Respir J 2007; 30: 452-456
Year: 2007



Distribution of biomarkers in severe asthma and severe uncontrolled asthma
Source: Virtual Congress 2021 – Pearls in asthma and respiratory burden research
Year: 2021



Effect of dupilumab on severe exacerbations in asthma patients with and without lung function improvements
Source: Virtual Congress 2020 – Monoclonal antibodies; randomised controlled trials and real-world studies in asthma
Year: 2020


Use of measurements of airway resistance in the determination of reversibility in patients with emphysema associated with alpha-1-antitrypsin (A1ATD) deficiency
Source: Eur Respir J 2001; 18: Suppl. 33, 205s
Year: 2001