mRNA sequencing of educated platelets generates a diagnostic biomarker for discrimination between pre- and post-capillary pulmonary hypertension.

M. Arkani (Amsterdam, Netherlands), S. Jansen (Amsterdam, Netherlands), S. In'T Veld (Amsterdam, Netherlands), J. Smits (Amsterdam, Netherlands), E. Post (Amsterdam, Netherlands), K. Zwaan (Amsterdam, Netherlands), J. Ramaker (Amsterdam, Netherlands), F. S. De Man (Amsterdam, Netherlands), A. Vonk Noordegraaf (Amsterdam, Netherlands), M. Best (Amsterdam, Netherlands), T. Wurdinger (Amsterdam, Netherlands), H. Bogaard (Amsterdam, Netherlands)

Source: Virtual Congress 2020 – Clinical evaluation, biomarkers and risk assessment of pulmonary hypertension
Session: Clinical evaluation, biomarkers and risk assessment of pulmonary hypertension
Session type: E-poster session
Number: 1526

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Arkani (Amsterdam, Netherlands), S. Jansen (Amsterdam, Netherlands), S. In'T Veld (Amsterdam, Netherlands), J. Smits (Amsterdam, Netherlands), E. Post (Amsterdam, Netherlands), K. Zwaan (Amsterdam, Netherlands), J. Ramaker (Amsterdam, Netherlands), F. S. De Man (Amsterdam, Netherlands), A. Vonk Noordegraaf (Amsterdam, Netherlands), M. Best (Amsterdam, Netherlands), T. Wurdinger (Amsterdam, Netherlands), H. Bogaard (Amsterdam, Netherlands). mRNA sequencing of educated platelets generates a diagnostic biomarker for discrimination between pre- and post-capillary pulmonary hypertension.. 1526

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Differential expression of miRNAs present in plasma and contained within circulating microparticles in precapillary pulmonary hypertension.
Source: International Congress 2019 – Pulmonary hypertension: novelties from the bench
Year: 2019


A point-of-care brain natriuretic peptide assay in the risk stratification and management of patients with pulmonary arterial hypertension
Source: Eur Respir J 2006; 28: Suppl. 50, 48s
Year: 2006

Impact of the state of endothelium on clinical and functional parameters in COPD patients with arterial hypertension.
Source: International Congress 2017 – Novel mechanisms and treatments for COPD
Year: 2017




Analysis of miRNA profile in circulating microparticles of patients with pulmonary arterial hypertension
Source: International Congress 2015 – Pulmonary hypertension: rare and hereditary causes of PAH
Year: 2015

Differential diagnosis of pre- and post-capillary pulmonary hypertension: the OPTICS study and other strategies
Source: Virtual Congress 2021 – Pulmonary vascular diseases
Year: 2021


Proteomic profiling identifies an exercise signature in patients with pulmonary arterial hypertension
Source: Virtual Congress 2020 – Exercise and haemodynamics in pulmonary hypertension
Year: 2020


Circulating collagen biomarker and quality of life in pulmonary arterial hypertension
Source: Annual Congress 2010 - Pulmonary circulation I
Year: 2010

The use of non-invasive stroke volume measurement to assess treatment response in pulmonary arterial hypertension
Source: Annual Congress 2010 - Pulmonary vascular diseases
Year: 2010

Circulating endothelial cell levels decrease after vasodilator therapy and are a biomarker of clinical worsening in refractory pulmonary hypertension in children
Source: Annual Congress 2012 - Pulmonary circulation: clinical aspects of PAH, PTE and CTEPH
Year: 2012

A novel echo-score for evaluating the pre-test probability of pre-capillary versus post-capillary pulmonary hypertension
Source: Annual Congress 2012 - Pulmonary circulation: end-points and biomarkers
Year: 2012

Pulmonary arteriole gene expression signature in idiopathic pulmonary fibrosis
Source: Eur Respir J 2013; 41: 1324-1330
Year: 2013



Expression of fetal genes in pulmonary arterial hypertension
Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms
Year: 2005


Endothelin-1 and endothelin-3 plasma levels in severe idiopathic pulmonary arterial hypertension
Source: Annual Congress 2005 - Pulmonary hypertension: pathophysiology
Year: 2005


RNA expression pattern of peripheral blood B-lymphocytes in idiopathic pulmonary arterial hypertension
Source: Annual Congress 2007 - Pathogenesis and novel therapeutic targets in pulmonary hypertension
Year: 2007


Current practice for determining pulmonary capillary wedge pressure predisposes to serious errors in the classification of patients with pulmonary hypertension
Source: Annual Congress 2011 - Clinical characteristics of patients with pulmonary hypertension
Year: 2011

Dipyridamole as adjuvant therapy in patients with pulmonary arterial hypertension. A pilot study
Source: Annual Congress 2007 - Pulmonary hypertension: diagnosis and treatment
Year: 2007



NT-proBNP variation in stable pulmonary arterial hypertension patients.
Source: International Congress 2018 – Pulmonary hypertension in lung diseases and the role of the right ventricle
Year: 2018


The comparison of diagnostic relevance of protein C, C-reactive protein and endothelin-1 for prediction of lung vessel thrombosis in patients with community-acquired pneumonia
Source: International Congress 2019 – Complex respiratory infections in clinical practice
Year: 2019


Cardiopulmonary exercise testing for detection of early pulmonary vascular changes in relatives of patients with idiopathic pulmonary arterial hypertension
Source: Annual Congress 2007 - Clinical aspects of pulmonary arterial hypertension
Year: 2007