Macrophages in lung and innervating ganglia express TLR7 and release nitric oxide

B. Proskocil (Portland, United States of America), A. Fryer (Portland, United States of America), D. Jacoby (Portland, United States of America), M. Drake (Portland, United States of America)

Source: Virtual Congress 2020 – Host-microbe interactions and their influence on lung disease onset and severity
Session: Host-microbe interactions and their influence on lung disease onset and severity
Session type: E-poster session
Number: 1065
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
B. Proskocil (Portland, United States of America), A. Fryer (Portland, United States of America), D. Jacoby (Portland, United States of America), M. Drake (Portland, United States of America). Macrophages in lung and innervating ganglia express TLR7 and release nitric oxide. 1065

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Colocalization of substance P/nitric oxide synthase in vagal-sensory and tyrosine hydroxylase/neuropeptide Y in sympathetic neurons projecting to the murine lung
Source: Eur Respir J 2001; 18: Suppl. 33, 244s
Year: 2001

Characterization of toll-like receptor 7 (TLR7) expression on airway nerves
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015


Nitric oxide (NO) modulates ICAM-1 expression and function and MCP-1 secretion in human airway epithelium
Source: Eur Respir J 2005; 26: Suppl. 49, 99s
Year: 2005

L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro
Source: Eur Respir J 2001; 18: 667-671
Year: 2001



Inhaled nitric oxide decreases pulmonary endothelial nitric oxide synthase expression and activity in normal newborn rat lungs
Source: ERJ Open Res 2016
Year: 2016


Role of endogenous nitric oxide in antigen-induced contractions
Source: Eur Respir J 2002; 20: Suppl. 38, 620s
Year: 2002

Inhaled no decreased endothelial nitric oxide synthase expression in normal newborn rat lungs
Source: Annual Congress 2009 - Respiratory disorders of the newborn
Year: 2009


Activation of TLR3 augments the production of MMPs in human lung fibroblasts via iuducible NOS dependent pathway
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

Experimental airways hyperreactivity and modulation of glutamatergic and nitrergic signalling
Source: Annual Congress 2013 –Novel drugs and biomarkers in respiratory medicine
Year: 2013


Involvement of nitric oxide, proinflammatory cytokines and effector cells in the inflammatory process in COPD patients
Source: Eur Respir J 2005; 26: Suppl. 49, 54s
Year: 2005

Differential regulation of two distinct isoforms of inducible nitric oxide synthases by lipopolysaccharide in guinea-pig lung and colon
Source: Eur Respir J 2001; 18: Suppl. 33, 197s
Year: 2001

Augmented lower respiratory tract nitric oxide production in eNOS deficient mice is related to upregulation of pulmonary iNOS expression
Source: Eur Respir J 2001; 18: Suppl. 33, 253s
Year: 2001

Different effects of cNOS and iNOS-derived nitric oxide in lung mechanics in a model of chronic airway inflammation in guinea pigs: modulation by neuropeptides
Source: Eur Respir J 2005; 26: Suppl. 49, 558s
Year: 2005

Nitric oxide attenuates the Th1 cells that are upregulated in patients with active pulmonary tuberculosis
Source: Eur Respir J 2001; 18: Suppl. 33, 466s
Year: 2001

Gene expression of Lewis lung tumor cells in response to cytokine mixture via nitric oxide
Source: Eur Respir J 2006; 28: Suppl. 50, 811s
Year: 2006

Measurement of nitric oxide levels in stimulated nasal mucosa
Source: Eur Respir J 2003; 22: Suppl. 45, 457s
Year: 2003

Measurement of nitric oxide levels in stimulated nasal mucosa
Source: Eur Respir J 2004; 24: Suppl. 48, 471s
Year: 2004

Nitric oxide production by the alveolar compartment of the lungs in cirrhotic patients
Source: Eur Respir J 2009; 34: 138-144
Year: 2009



Nitric oxide is a poor bronchodilator but reduces release of leukotrienes in the peripheral airways
Source: Eur Respir J 2005; 26: Suppl. 49, 128s
Year: 2005

Nitric oxide promotes apoptosis in IL-5-treated human eosinophils
Source: Eur Respir J 2001; 18: Suppl. 33, 476s
Year: 2001