LSC - 2020 - Mitochondrial dysfunction induce immunoproteasome and MHC class I responses in lung aging

X. Wang (Munich, Germany)

Source: Virtual Congress 2020 – Chronic lung diseases: novel methods, diagnostics and biomarkers
Session: Chronic lung diseases: novel methods, diagnostics and biomarkers
Session type: E-poster session
Number: 328
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
X. Wang (Munich, Germany). LSC - 2020 - Mitochondrial dysfunction induce immunoproteasome and MHC class I responses in lung aging. 328

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Mitochondrial dysfunction activates MHC class I adaptive immune responses in lung aging
Source: International Congress 2019 – Cellular metabolism and immune senescence in lung pathology
Year: 2019



LSC - 2021 - Mitochondrial DNA stress activates MHC class I antigen presentation and CD8+ T-cell immunity: implications for pulmonary fibrosis
Source: Virtual Congress 2021 – Molecular pathology and cell biology of pulmonary diseases
Year: 2021

PP209 – Mitochondrial DNA stress activates MHC class I antigen presentation and CD8+ Tcell immunity: implications for pulmonary fibrosis
Source: ERS Lung Science Conference 2021
Year: 2021

Mitochondrial DNA stress activates MHC class I antigen presentation and CD8+ T-cell immunity: implications for pulmonary fibrosis
Source: Virtual Congress 2021 – Emerging new mechanisms of chronic lung disease
Year: 2021

LSC - 2020 - Extracellular vesicles produced by bronchial epithelial cells in response to oxidative stress contain micro-RNAs associated with senescence
Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies
Year: 2020


LSC - 2020 - IRF5 regulates airway macrophage metabolic responses to viral challenge
Source: Virtual Congress 2020 – Translational science in respiratory infections
Year: 2020


LSC - 2020 - The role of the COPD susceptibility gene FAM13A in barrier function and pro-inflammatory responses of human airway epithelial cells
Source: Virtual Congress 2020 – Inflammatory pathways in chronic airway diseases
Year: 2020


LSC - 2020 - Caspase-1 activation by cigarette smoke occurs via TLR4/TRIF/caspase-8 axis leading to metabolic alterations in human macrophages
Source: Virtual Congress 2020 – Effects of environmental exposures on lung pathology
Year: 2020


LSC - 2020 - Altered metabolic activity and redox balance are associated with a proliferative phenotype in COPD airway smooth muscle cells.
Source: Virtual Congress 2020 – Metabolic alterations and ageing in lung disease
Year: 2020




NKG2D-dependent effector function of bronchial epithelium-activated alloreactive T-cells
Source: Eur Respir J 2008; 32: 563-570
Year: 2008



A hypothesis for the initiation of COPD
Source: Eur Respir J 2009; 33: 310-315
Year: 2009



Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome
Source: Eur Respir J, 59 (3) 2102557; 10.1183/13993003.02557-2021
Year: 2022



Evidence for cell mediated immune dysfunction in the COPD lung: The role of cytotoxic CD4+ T cells
Source: International Congress 2015 – Viral infections: basic research and clinical perspective
Year: 2015

Elastin peptides modulate T helper response during murine emphysema
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Rhinovirus infection differentially modulates MHC class I-related chain (MIC) A and B molecules in human respiratory epithelial cells
Source: Annual Congress 2009 - Viruses and respiratory infections: prevalence and mechanisms of infection
Year: 2009


Inflammation induced conformational changes in Z alpha-1 antirypsin promotes lung Z-AT cell damage
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013

Complex alterations of lung dendritic cell subsets across distinct asthma phenotypes
Source: International Congress 2015 – Immune aspects of asthma and other airway diseases
Year: 2015

Steroid resistance in COPD is associated with impaired molecular chaperone HSP90 expression by pro-inflammatory lymphocytes
Source: International Congress 2016 – Mechanisms of disease
Year: 2016


LSC - 2017 - The role of the epigenetic regulator HMGN5 in COPD resulting from chronic lung injury
Source: International Congress 2017 – Functional genomics knowledge in parenchymal and bronchial diseases
Year: 2017



LSC - 2020 - Cigarette smoke exposure disrupts the molecular regulation of mitochondrial metabolism in human bronchial and alveolar epithelial cells
Source: Virtual Congress 2020 – Effects of environmental exposures on lung pathology
Year: 2020