Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension

Robert A. Lewis, A.A. Roger Thompson, Catherine G. Billings, Athanasios Charalampopoulos, Charlie A. Elliot, Neil Hamilton, Catherine Hill, Judith Hurdman, Smitha Rajaram, Ian Sabroe, Andy J. Swift, David G. Kiely, Robin Condliffe

Source: Eur Respir J, 55 (6) 2000041; 10.1183/13993003.00041-2020
Journal Issue: June
Disease area: Interstitial lung diseases, Pulmonary vascular diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Robert A. Lewis, A.A. Roger Thompson, Catherine G. Billings, Athanasios Charalampopoulos, Charlie A. Elliot, Neil Hamilton, Catherine Hill, Judith Hurdman, Smitha Rajaram, Ian Sabroe, Andy J. Swift, David G. Kiely, Robin Condliffe. Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. Eur Respir J, 55 (6) 2000041; 10.1183/13993003.00041-2020

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The change of lung diffusion capacity does not influence the prognosis in patients with pulmonary arterial hypertension associated with systemic sclerosis.
Source: International Congress 2019 – Endpoints and risk assessment of pulmonary arterial hypertension
Year: 2019



Histopathology of idiopathic pulmonary arterial hypertension in patients with low or normal diffusion capacity
Source: Annual Congress 2012 - Pulmonary circulation: clinical end-points and clinical physiology
Year: 2012

Severely reduced diffusion capacity in idiopathic pulmonary arterial hypertension: patient characteristics and treatment responses
Source: Eur Respir J 2013; 42: 1575-1585
Year: 2013



‘Idiopathic‘ pulmonary arterial hypertension with preserved lung function but co-existing parenchymal abnormalities: Response to treatment and survival
Source: Annual Congress 2012 - Pulmonary circulation: clinical databases and registries
Year: 2012

Severe pulmonary hypertension in lung disease: phenotypes and response to treatment
Source: Eur Respir J 2015; 46: 1378-1389
Year: 2015



Impact of long-term oxygen therapy on systemic inflammation, morphological changes of red blood cells, pulmonary hemodynamics and diaphragm function in patients with chronic obstructive pulmonary disease.
Source: International Congress 2018 – Integrated care and non-pharmacological management of COPD
Year: 2018


Pulmonary function measures predict mortality differently in IPF versus combined pulmonary fibrosis and emphysema
Source: Eur Respir J 2011; 37: 176-183
Year: 2011



Clinical characteristics, haemodynamics, and survival in patients with combined pulmonary fibrosis and emphysema and associated pulmonary hypertension
Source: Annual Congress 2008 - Pulmonary vascular medicine
Year: 2008

A potential role for sildenafil in the management of pulmonary hypertension associated with parenchymal lung disease
Source: Eur Respir J 2006; 28: Suppl. 50, 425s
Year: 2006

Coexistent pulmonary emphysema delays the decrease in vital capacity in patients with idiopathic pulmonary fibrosis
Source: Annual Congress 2008 - Miscellaneous aspects of interstitial lung disease
Year: 2008


Determination of pulmonary hypertension degree in patients with interstitial lung diseases
Source: Annual Congress 2010 - Different patterns of interstitial lung disease
Year: 2010

Acute exacerbations and pulmonary hypertension in advanced idiopathic pulmonary fibrosis
Source: Eur Respir J 2012; 40: 93-100
Year: 2012



The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension
Source: Eur Respir J, 51 (1) 1701214; 10.1183/13993003.01214-2017
Year: 2018



Is survival in patients with severe group 3 pulmonary hypertension influenced by targeted therapy?
Source: International Congress 2015 – Pulmonary hypertension: novel clinical insights
Year: 2015

Pulmonary vascular resistance predicts mortality in patients with pulmonary hypertension associated with interstitial lung disease: results from the COMPERA registry
Source: Eur Respir J, 58 (2) 2101483; 10.1183/13993003.01483-2021
Year: 2021



Bosentan for sarcoidosis associated pulmonary arterial hypertension (BoSAPH) was effective in advanced parenchymal lung disease
Source: Annual Congress 2012 - Sarcoidosis
Year: 2012



Baseline characteristics and survival of patients with pulmonary hypertension in interstitial lung disease in the “HYPID” study
Source: Annual Congress 2013 –Pulmonary circulation: clinical physiology
Year: 2013

Prevalence and impact of WHO group 3 pulmonary hypertension in advanced idiopathic nonspecific interstitial pneumonia
Source: Eur Respir J, 52 (1) 1800545; 10.1183/13993003.00545-2018
Year: 2018



Response to PAH specific therapy in systemic sclerosis patients with extensive parenchymal changes and pulmonary hypertension
Source: Virtual Congress 2020 – Pulmonary hypertension in lung diseases
Year: 2020


Diaphragm dysfunction in combination with lung function decline is associated with higher mortality in idiopathic pulmonary fibrosis patients
Source: International Congress 2018 – Consequences of idiopathic interstitial pneumonias
Year: 2018