Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target

Michael J. Hughes, Helen M. McGettrick, Elizabeth Sapey

Source: Eur Respir Rev, 29 (155) 190102; 10.1183/16000617.0102-2019
Journal Issue: March
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Michael J. Hughes, Helen M. McGettrick, Elizabeth Sapey. Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target. Eur Respir Rev, 29 (155) 190102; 10.1183/16000617.0102-2019

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The evaluation of systemic inflammation in COPD patients comorbided with cardiovascular diseases or diabetes mellitus
Source: Annual Congress 2011 - Respiratory epidemiology: comorbidity
Year: 2011

COPD: inflammatory mechanisms and systemic consequences
Source: Eur Respir Mon 2013; 59: 13-27
Year: 2013


The impact of aging on COPD, cardiovascular comorbidities and systemic inflammation
Source: International Congress 2019 – Cardiovascular comorbidities in COPD
Year: 2019

Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD
Source: Eur Respir J 2008; 32: 962-969
Year: 2008



Metabolic syndrome and diabetes mellitus in COPD
Source: Eur Respir Mon 2013; 59: 117-134
Year: 2013


Approach to the diagnostics of early carbon metabolism disorders and diabetes mellitus 2 type in COPD patients
Source: Annual Congress 2013 –COPD diagnosis
Year: 2013

COPD, an inflammatory systemic disease. Inflammatory parameters in a group of COPD patients
Source: International Congress 2014 – Lung function, COPD and inflammation
Year: 2014

Potential association between pulmonary hypertension in COPD and monocyte chemoattractant protein (MCP)-1
Source: Annual Congress 2005 - Pulmonary hypertension: pathophysiology
Year: 2005


Inflammatory markers of atherogenesis in patients with uncontrolled severe asthma
Source: International Congress 2017 – Current molecular and genetic understanding of lung diseases
Year: 2017


Is there a strong relationship between COPD and cardiovascular diseases?
Source: Annual Congress 2013 –The latest insights in respiratory muscles, neuromuscular disease and comorbidities
Year: 2013

Fructosamine-3-Kinase: A molecular link between COPD and diabetes regulating carbonyl stress and the impact of metformin treatment
Source: International Congress 2015 – New insights into lung disease pathogenesis
Year: 2015


Cardiovascular risk, subclinical atherosclerosis and markers of systemic inflammation in patients with COPD and frequent exacerbator phenotype
Source: International Congress 2016 – Monitoring comorbidities
Year: 2016


Subphenotyping COPD: is it relevant for therapeutic intervention and disease outcome?
Source: Annual Congress 2005 - Inflammatory phenotypes of asthma and COPD: the end of traditional diagnosis, or not?
Year: 2005

Some pathogenetic mechanisms of inflammatory processes in smoking patients with COPD
Source: Annual Congress 2007 - Smoking and the lung
Year: 2007


The level of anti-inflammatory cytokine IL-10 in patients with chronic obstructive pulmonary disease of varying severity
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013


Complexity in chronic asthma and COPD: implications for risk assessment, disease progression and control
Source: Annual Congress 2008 - A step-change in asthma. The Lancet/ERS symposium
Year: 2008


ß2-adrenoceptor modulation in COPD and its potential impact on cardiovascular comorbidities
Source: Eur Respir Monogr 2020; 88: 229-237
Year: 2020


Elevated circulating CTLA-4 level in patients with COPD is related to systemic inflammation and disease severity
Source: Annual Congress 2013 –COPD: markers and inflammation
Year: 2013



Metabolic regulation during the co-existence of COPD and DM type2
Source: International Congress 2016 – Features and impact of comorbidities in COPD
Year: 2016


Increased oxidative stress in patients with chronic obstructive pulmonary disease (COPD) and metabolic syndrome (MetS)
Source: Annual Congress 2013 –Translational studies in chronic lung diseases: from bedside to bench
Year: 2013