Levels of CD4CD25 T regulatory cells in bronchial mucosa and peripheral blood of chronic obstructive pulmonary disease indicate involvement of autoimmunity mechanisms

V. Sileikiene (Vilnius, Lithuania), A. Laurinaviciene (Vilnius, Lithuania), D. Lesciute-Krilaviciene (Vilnius, Lithuania), L. Jurgauskiene (Vilnius, Lithuania), J. Norkuniene (Vilnius, Lithuania), A. Laurinavicius (Vilnius, Lithuania)

Source: International Congress 2019 – Immunopathological mechanisms of lung disease
Session: Immunopathological mechanisms of lung disease
Session type: Thematic Poster
Number: 4102
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
V. Sileikiene (Vilnius, Lithuania), A. Laurinaviciene (Vilnius, Lithuania), D. Lesciute-Krilaviciene (Vilnius, Lithuania), L. Jurgauskiene (Vilnius, Lithuania), J. Norkuniene (Vilnius, Lithuania), A. Laurinavicius (Vilnius, Lithuania). Levels of CD4CD25 T regulatory cells in bronchial mucosa and peripheral blood of chronic obstructive pulmonary disease indicate involvement of autoimmunity mechanisms. 4102

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Pulmonary dendritic cells from chronic obstructive pulmonary disease patients suppress lung immune responses through induction of regulatory T cells
Source: Annual Congress 2011 - T-cell subsets
Year: 2011

The role of regulator and effector T lymphocytes in chronic obstructive pulmonary disease and lung cancer
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Decreased TCR γδ T lymphocytes in patients with chronic obstructive pulmonary disease
Source: Eur Respir J 2003; 22: Suppl. 45, 85s
Year: 2003

Lung dendritic cells from chronic obstructive pulmonary disease patients induce type 1 T regulatory cells
Source: Annual Congress 2012 - Immunologic mechanisms in COPD and asthma
Year: 2012


Exhausted T lymphocytes in chronic obstructive pulmonary disease: single-cell analysis of human lung tissue
Source: Virtual Congress 2021 – Emerging new mechanisms of chronic lung disease
Year: 2021


Increased CD4+ T-cell infiltration in bronchial epithelium of patients with chronic obstructive pulmonary disease
Source: Annual Congress 2007 - Epithelial networks in the airways
Year: 2007


A high probability of short-range interactions between fibrocytes and CD8+ T cells potentiates the inflammatory response in chronic obstructive pulmonary disease (COPD) lungs
Source: Virtual Congress 2020 – Host-microbe interactions and their influence on lung disease onset and severity
Year: 2020


Regulator and effector T lymphocytes in late stages of non small cell lung cancer and chronic obstructive pulmonary disease
Source: Annual Congress 2012 - New aspects of lung cancer biology
Year: 2012

Decreased FOXP3 expression in small airways of smokers with COPD
Source: Eur Respir J 2009; 33: 61-67
Year: 2009



High percentage of CD8+ effector T lymphocytes in patients with chronic obstructive pulmonary disease
Source: Eur Respir J 2002; 20: Suppl. 38, 591s
Year: 2002

A high probability of short-range interactions between fibrocytes and CD8 T cells in chronic obstructive pulmonary disease (COPD) lungs
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019

Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
Source: Eur Respir J 2001; 17: 946-953
Year: 2001



Apoptosis and activation of peripheral blood neutrophils in chronic obstructive pulmonary disease
Source: Eur Respir J 2001; 18: Suppl. 33, 74s
Year: 2001

Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis
Source: Eur Respir J 2016; 48: 1171-1183
Year: 2016



T regulatory cells within inflammatory foci of COPD lungs
Source: Annual Congress 2008 - Invasive and noninvasive measurements of lung inflammation
Year: 2008


STAT4 activation in smokers and patients with chronic obstructive pulmonary disease
Source: Eur Respir J 2004; 24: 78-85
Year: 2004



Role of regulatory T-cells (Tregs) in bacterial infection-induced lung fibrosis exacerbation in mice
Source: International Congress 2018 – Pulmonary fibrosis: from models to patients
Year: 2018

Peripheral blood Th17 and Th17/Th2 cells and their association with lung function and biomarkers in asthma-COPD overlap syndrome
Source: International Congress 2017 – Systemic and airway biomarkers
Year: 2017

Increased regulatory T cells in the blood of patients with idiopathic pulmonary arterial hypertension
Source: Eur Respir J 2006; 28: Suppl. 50, 659s
Year: 2006

Decreased pulmonary immunoregulatory/suppressor (CD4+CD25+) T-lymphocytes in chronic obstructive pulmonary disease
Source: Eur Respir J 2003; 22: Suppl. 45, 85s
Year: 2003