A549 cell promotes the proliferation and migration of fibroblast through FXR pathway

H. Jiang (Shanghai, China), F. Wang (Qingdao, China)

Source: International Congress 2019 – Biology of lung cancer
Session: Biology of lung cancer
Session type: Poster Discussion
Number: 3671
Disease area: Thoracic oncology

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Jiang (Shanghai, China), F. Wang (Qingdao, China). A549 cell promotes the proliferation and migration of fibroblast through FXR pathway. 3671

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Bradykinin-induced fibroblast proliferation and myofibroblast differentiation via B2 receptor pathway
Source: Eur Respir J 2005; 26: Suppl. 49, 342s
Year: 2005

Interleukin-8 stimulates human airway epithelial cell proliferation through EGFR transactivation
Source: Eur Respir J 2003; 22: Suppl. 45, 561s
Year: 2003

In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation
Source: Annual Congress 2012 - Diffuse parenchymal lung disease I
Year: 2012

Effective LncRNAs on myofibroblast differentiation in human A549 cell line treated with TGF-ß
Source: International Congress 2018 – Pulmonary fibrosis: from models to patients
Year: 2018

Selective inhibition of COX-2 by celecoxib exerts negative effects on endothelial progenitor cell proliferation and stimulates apoptosis in vitro
Source: Eur Respir J 2005; 26: Suppl. 49, 368s
Year: 2005

KPNB1-mediated PD-L1 nuclear translocation promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signalling pathway
Source: Virtual Congress 2020 – Biological mechanisms of lung cancer
Year: 2020

Inhibition of insulin-like growth factor type I (IGF-I) gene in A549 human lung cancer cell line enhances cell apoptosis and causes phenotype changes relevant to increased tumor susceptibility to immune system
Source: Eur Respir J 2007; 30: Suppl. 51, 715s
Year: 2007

P2X7 receptor regulates cell survival, inflammation processes and proliferation of lung carcinoma cells
Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease
Year: 2019

Retinoic acid abrogation of TNF-alpha-induced growth arrest in lung alveolar epithelial cells is linked to p21 (CIP1) downregulation
Source: Eur Respir J 2001; 18: Suppl. 33, 477s
Year: 2001

Lipoxin A4 promotes lung epithelial repair whilst inhibiting fibroblast proliferation
Source: ERJ Open Res 2016: 00079-2015
Year: 2016



Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts
Source: Eur Respir J 2006; 28: Suppl. 50, 662s
Year: 2006

Hypoxia induces IL-1β and TNF-α expressionin of U937 cells involving PKCα/RAF-1/MAPK/NF-κB pathway
Source: Eur Respir J 2005; 26: Suppl. 49, 102s
Year: 2005

Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair
Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury
Year: 2008


VEGF induces ECM synthesis and fibroblast activity in human lung fibroblasts
Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology
Year: 2017

Lung-derived mesenchymal stem cells induce the secretion of hepatocyte growth factor in fibroblasts
Source: International Congress 2017 – Anti-inflammatory and pro-repair mediators in acute lung injury
Year: 2017


Blocking VEGF does not induce proapoptotic effects in the NSCLC cell line A549
Source: Annual Congress 2010 - New insights in the pathology of lung cancer
Year: 2010


SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescence
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013

Cell cycle regulation of IPF-derived lung fibroblasts is dependent on RhoA signalling
Source: Eur Respir J 2005; 26: Suppl. 49, 102s
Year: 2005

Inhibitory effects of shRNA targeting layilin on adhesion and invasion behavior of human lung carcinoma cell A549 induced by hyaluronan in vitro
Source: Eur Respir J 2006; 28: Suppl. 50, 855s
Year: 2006