Dual bronchodilation with tiotropium/olodaterol further reduces activity-related breathlessness versus tiotropium alone in COPD

François Maltais, Joseph-Leon Aumann, Anne-Marie Kirsten, Éric Nadreau, Hemani Macesic, Xidong Jin, Alan Hamilton, Denis E. O'Donnell

Source: Eur Respir J, 53 (3) 1802049; 10.1183/13993003.02049-2018
Journal Issue: March
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
François Maltais, Joseph-Leon Aumann, Anne-Marie Kirsten, Éric Nadreau, Hemani Macesic, Xidong Jin, Alan Hamilton, Denis E. O'Donnell. Dual bronchodilation with tiotropium/olodaterol further reduces activity-related breathlessness versus tiotropium alone in COPD. Eur Respir J, 53 (3) 1802049; 10.1183/13993003.02049-2018

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Dual bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE study
Source: Eur Respir J 2014; 43: 1599-1609
Year: 2014



Effectiveness of salmeterol versus ipratropium bromide on exertional dyspnoea in COPD
Source: Eur Respir J 2001; 17: 1132-1137
Year: 2001



Effects of tiotropium and salmeterol/fluticasone combination on lung hyperinflation, dyspnea and exercise tolerance in COPD
Source: Eur Respir J 2006; 28: Suppl. 50, 33s
Year: 2006

Dual bronchodilation with once-daily QVA149 reduces exacerbations, improves lung function and health status versus glycopyrronium and tiotropium in severe-to-very severe COPD patients: The SPARK study
Source: Annual Congress 2013 –New bronchodilators for COPD management
Year: 2013

Dual bronchodilation with once-daily QVA149 improves lung function and reduces exacerbations in patients with COPD: The IGNITE trials
Source: Annual Congress 2013 –New clinical trials of asthma and COPD drugs
Year: 2013

Improvement in dyspnea with fluticasone/salmeterol compared with salmeterol or ipratropium in patients with COPD
Source: Eur Respir J 2004; 24: Suppl. 48, 88s
Year: 2004

Metronome-paced hyperventilation, CT measurements and exercise to investigate dynamic hyperinflation contrasting tiotropium versus indacaterol treatment in moderate COPD patients
Source: International Congress 2015 – Unravelling the mechanisms of symptoms and exercise limitationas in disease
Year: 2015


Effectiveness of indacaterol and tiotropium in patients with severe dyspnoea
Source: Annual Congress 2012 - COPD treatments: efficacy and safety
Year: 2012


Acute effect of formoterol, salmeterol, albuterol, oxitropium bromide and placebo on FEV1, inspiratory capacity and dyspnoea in COPD patients
Source: Eur Respir J 2001; 18: Suppl. 33, 380s
Year: 2001

Nebulized formoterol improves airway function in COPD subjects receiving maintenance tiotropium
Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma
Year: 2008

Improvement of dyspnoea following of six months treatment with tiotropium but not with salmeterol in patients with COPD
Source: Eur Respir J 2001; 18: Suppl. 33, 26s
Year: 2001

Effects of acute dual bronchodilator treatment (tiotropium + olodaterol) on cardiopulmonary interactions in hyperinflated patients with COPD
Source: International Congress 2018 – Advances in exercise physiopathology
Year: 2018



Comparison of spirometric efficacy of fluticasone/salmeterol plus tiotropium and tiotropium alone in moderate COPD
Source: Annual Congress 2009 - New bronchodilators
Year: 2009


Influence of tiotropium bromid on airway inflammation and symptom in COPD patients
Source: Annual Congress 2011 - Bronchodilators in asthma and COPD
Year: 2011

Comparative effects of formoterol monotherapy versus formoterol plus tiotropium on dynamic hyperinflation and exercise tolerance in COPD
Source: Annual Congress 2009 - Influence of interventions and comorbidity on exercise performance
Year: 2009



Efficacy of tiotropium and indacaterol alone or the combination on dynamic lung hyperinflation and exercise tolerance in COPD
Source: International Congress 2014 – Asthma and COPD management
Year: 2014


Effect of fluticasone propionate/salmeterol on exercise endurance in moderate-severe COPD
Source: Annual Congress 2012 - COPD treatment and varia
Year: 2012

Once-daily QVA149 demonstrates superior improvements in patient-reported dyspnea compared to tiotropium in patients with moderate-to-severe COPD: The BLAZE study
Source: Annual Congress 2013 –Asthma and COPD management: novel clinical findings
Year: 2013


Bronchodilator efficacy of tiotropium in patients with mild COPD
Source: Eur Respir J 2006; 28: Suppl. 50, 616s
Year: 2006

Effect of fluticasone propionate/salmeterol plus tiotropium versus tiotropium on walking endurance in COPD
Source: Eur Respir J 2013; 42: 539-541
Year: 2013