Valved holding chamber (VHC) angle can affect pressurized netered-dose inhaler (pMDI) medication delivery efficiency

J. Suggett (London, Canada), M. Nagel (London, Canada), V. Avvakoumova (London, Canada), J. Mitchell (London, Canada)

Source: International Congress 2018 – Determinants and monitoring of asthma control
Session: Determinants and monitoring of asthma control
Session type: Poster Discussion
Number: 5487
Disease area: Airway diseases

Congress or journal article abstractWebcastSlide presentationE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. Suggett (London, Canada), M. Nagel (London, Canada), V. Avvakoumova (London, Canada), J. Mitchell (London, Canada). Valved holding chamber (VHC) angle can affect pressurized netered-dose inhaler (pMDI) medication delivery efficiency. 5487

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Assessment of the suitability of filters for use in clinical studies with an HFA fluticasone propionate pressurized metered dose inhaler (pMDI) and a valved holding chamber (VHC)
Source: Annual Congress 2011 - Lung function today and tomorrow II
Year: 2011

In vitro comparison of aerosol characteristics of HFA albuterol (salbutamol) pressurized metered dose inhaler (pMDI) formulation from three valved holding chambers (VHCs)
Source: Annual Congress 2011 - Drug delivery and pharmacokinetics II
Year: 2011

In vitro equivalence exists for infant non-conducting (NC) and anti-static (AS) valved holding chambers (VHC) from the same family of add on devices used with pressurized metered dose inhalers (pMDIs) provided pre-conditioning of the non-conducting VHCs is undertaken
Source: Annual Congress 2010 - Drug delivery and pharmacokinetics I
Year: 2010


In vitro aerosol delivery by vibrating mesh nebulizer (VMN) and pressurized metered dose inhaler (pMDI) using spacers in comparison with T adapters in mechanical ventilation.
Source: Respiratory Failure and Mechanical Ventilation Conference 2020
Year: 2020



Laboratory assessment of drug delivery of Beclomethasone/Formoterol metered dose inhaler (MDI) with a new valved holding chamber (VHC) designed specifically for 'on-the-go' use.
Source: Virtual Congress 2021 – Therapies for respiratory diseases in primary care and COVID - 19
Year: 2021


Impact of inhalation delay on medication delivery from a salbutamol HFA pressurized metered dose inhaler used with and without a new prototype portable valved holding chamber
Source: International Congress 2019 – COPD treatment: clinical trials, cohorts and inhaler device studies
Year: 2019

In vitro comparison of aerosol characteristics of HFA ipratropium bromide pressurized metered dose inhaler (pMDI) formulation from three valved holding chambers (VHCs)
Source: Annual Congress 2011 - Drug delivery and pharmacokinetics I
Year: 2011

In vitro evaluation of spacers in comparison with T-adapters in mechanical ventilation with pressurized metered dose inhalers (pMDI) and vibrating mesh nebulizer.
Source: International Congress 2019 – COPD and other specific entities in intensive care unit medicine
Year: 2019

In vitro testing of an improved collapsible valved holding chamber (CHC) with a pressurized metered-dose inhaler delivered bronchodilator, simulating an adult mechanically ventilated patient
Source: Annual Congress 2010 - Treatment options for asthma
Year: 2010


The in vitro fine particle dose with Symbicort Rapihaler pMDI is similar using either NebuChamber or AeroChamber Plus valved holding chamber spacer devices
Source: Eur Respir J 2005; 26: Suppl. 49, 504s
Year: 2005

The impact of different valved holding chambers (VHCs) on lung drug delivery: using functional respiratory imaging (FRI) and a single metered dose inhaler (MDI) type
Source: Virtual Congress 2020 – Diagnosis and management of airways disease in primary care
Year: 2020




Pressurised metered dose inhalers (pMDIs) with integrated flow rate guidance.
Source: International Congress 2017 – Pulmonary drug and devices delivery
Year: 2017


Comparison of proficiency of pressurized metered dose inhaler (pMDI) use with asthma control
Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma
Year: 2008


Feedback during treatment results in increased adherence when using a pressurized metered dose inhaler with valved holding chamber in paediatric patients with asthma
Source: Annual Congress 2008 - Clinical aspects of asthma in school-aged children
Year: 2008

Pressurized Metered Dose Inhaler (pMDI) with holding chamber - Correct procedure
Source: Procedure Video 2018
Year: 2018

Antistatic treatment and the amount of salbutamol actuated have variable effect on drug delivery of six different valved holding chambers (VHC)
Source: International Congress 2019 – Severe acute asthma and troublesome wheezing
Year: 2019

Valved holding chambers (VHCs) can have different medication delivery performance as a function of delay interval following actuation of the pressurized metered dose inhaler (pMDI)
Source: International Congress 2014 – Respiratory symptoms in primary care populations
Year: 2014

Relative pulmonary bioavailability (BA) of fluticasone propionate/formoterol (FP/FORM) via pressurised metered-dose inhaler (pMDI) and a novel breath-triggered inhaler (BTI)
Source: International Congress 2017 – Pulmonary drug and devices delivery
Year: 2017


Comparison of a dry powder inhaler (DPI) to a pressurized metered-dose inhaler (pMDI) formulation of extra fine beclomethasone dipropionate/formoterol fumarate/glycopyrronium bromide (BDP/FF/GB) in patients with COPD: The TRI-D study.
Source: Virtual Congress 2020 – COPD : inhaled corticosteroids, bronchodilators and eosinophils
Year: 2020


Two-tone trainer maintains a slow inhalation rate when using a metered dose inhaler (MDI)
Source: Eur Respir J 2005; 26: Suppl. 49, 47s
Year: 2005