Source: International Congress 2018 – New insights in the signalling pathways that underlie IPF pathophysiology
Disease area: Interstitial lung diseases



Rating:

Share or cite this content

Citations should be made in the following way:
E. Marchal-Duval, A. Froidure (antoine.froidure@uclouvain.be / Fondation Saint-Luc UCL,Bruxelles), M. Jaillet (madeleine.jaillet@inserm.fr / INSERM U1152,Paris), M. Ghanem (mada.ghanem@inserm.fr / INSERM U1152,Paris), A. Joannes (audrey.joannes@inserm.fr / INSERM U1152,Paris), A. Maurac (arnaud.maurac@gmail.com / INSERM U1152,Paris), A. Cazes (aurelie.cazes@aphp.fr / Hôpital Bichat Service d'anatomopathologie,Paris), P. Mordant (pierre.mordant@aphp.fr / Hôpital Bichat Service de Chirurgie Thoracique,Paris), H. Mal (herve.mal@aphp.fr / Hôpital Bichat Service de Pneumologie B,Paris), B. Crestani (bruno.crestani@aphp.fr / Hôpital Bichat Service de Pneumologie A,Paris), A. Mailleux (arnaud.mailleux@inserm.fr / INSERM U1152,Paris). LSC - 2018 - PRRX1 a pro-fibrotic mesenchymal transcription factor modulated by remodeled microenvironment in IPF. 5346

Member's Comments

No comment yet.

Related content which might interest you: PRRX1 a pro-fibrotic mesenchymal transcription factor modulated by remodeled microenvironment in IPF Source: ERS Lung Science Conference 2018 Year: 2018 Reduced expression of the transcription factor KLF4 in COPD macrophages is associated with dysfunctional differentiation Source: International Congress 2017 – Translational studies of lung disease Year: 2017 The gene expression of the endothelial to mesenchymal transition-related transcription factor slug is increased in remodelled pulmonary arteries of COPD Source: Annual Congress 2010 - Pathobiology of pulmonary hypertension Year: 2010 Modulating progenitor accumulation attenuates lung angiogenesis in a mouse model of asthma Source: Eur Respir J 2011; 38: 679-687 Year: 2011 LSC - 2017 - A critical role for mTOR regulated metabolic reprogramming during TGF-ß induced fibroblast collagen synthesis Source: International Congress 2017 – Novel mechanisms and therapeutic targets in lung injury and repair Year: 2017 Decreased expression of FENDRR, a lung mesenchymal long non-coding RNA, regulates fibroblast phenotypes in IPF through NOX4. Source: International Congress 2017 – Functional genomics knowledge in parenchymal and bronchial diseases Year: 2017 Increased immunoreactivity of stromal cell-derived factor-1 and angiogenesis in asthma Source: Eur Respir J 2003; 21: 804-809 Year: 2003 LSC - 2018 - Impaired angiogenic supportive capacity and altered gene expression profile of CD146+ mesenchymal stromal cells isolated from hyperoxia-injured neonatal rat lungs Source: International Congress 2018 – Molecular and cellular determinants of the developing lung Year: 2018 Transcription factor FOXF1 induces cancer-associated fibroblast-like phenotype to promote lung cancer progression Source: Annual Congress 2009 - Pathogenesis of lung cancer Year: 2009 LSC - 2020 - pSTAT5-SOCS1 signalling as a novel pathway in macrophage metabolic reprogramming by Mesenchymal Stromal Cells (MSCs) in ARDS Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020 Airway epithelial cell IP-10 production is regulated by miR-31 via the transcription factor IRF-1 Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects Year: 2015 Transforming Growth factor beta-1 and Smad signaling has the potential to drive EMT-related changes in smokers and COPD Source: International Congress 2016 – How the understanding og molecular and genomic crosstalk is helping to diagnose lung disease Year: 2016 LSC - 2021 - Modeling idiopathic pulmonary fibrosis using induced pluripotent stem cell-derived alveolar epithelial organoids Source: Virtual Congress 2021 – In vitro modelling of lung disease: reach out to the next dimension Year: 2021 LSC - 2021 - Club cell functions as a Wnt-responsive progenitor for tissue repair in COPD Source: Virtual Congress 2021 – Molecular pathology and cell biology of pulmonary diseases Year: 2021 The mesenchymal gene, ADAM33, is not expressed during TGFβ-induced epithelial-mesenchymal transition (EMT) in lung epithelial cells Source: Eur Respir J 2007; 30: Suppl. 51, 60s Year: 2007 LSC - 2017 - mTOR-mediated cap-dependent translation is essential for human lung myofibroblast differentiation and collagen I synthesis Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis Year: 2017 Circulating MDSC modulate IPF progression by orchestrating immunosuppressive and pro-fibrotic networks Source: International Congress 2018 – Advanced profiling of immune cells in chronic lung diseases Year: 2018 IL-11 promotes pulmonary vascular remodeling and lung fibrosis through the activation of endothelial to mesenchymal transition. Source: Virtual Congress 2020 – Translational aspects of idiopathic pulmonary fibrosis Year: 2020 Jun kinase regulates the expression of TGF-beta induced connective tissue growth factor in human lung fibroblast Source: Annual Congress 2004 - Inflammation and remodelling in human lungs Year: 2004 The contribution of transforming growth factor-β and epidermal growth factor signalling to airway remodelling in chronic asthma Source: Eur Respir J 2006; 27: 208-229 Year: 2006