Valved holding chambers vary considerably in drug delivery efficacy

P. Csonka (Tampere, Finland), L. Lehtimaki (Tampere, Finland)

Source: International Congress 2018 – Paediatric asthma: prevention, diagnosis and treatment
Session: Paediatric asthma: prevention, diagnosis and treatment
Session type: Oral Presentation
Number: 340
Disease area: Airway diseases, Paediatric lung diseases

Congress or journal article abstractWebcastSlide presentationE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
P. Csonka (Tampere, Finland), L. Lehtimaki (Tampere, Finland). Valved holding chambers vary considerably in drug delivery efficacy. 340

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Antistatic treatment and the amount of salbutamol actuated have variable effect on drug delivery of six different valved holding chambers (VHC)
Source: International Congress 2019 – Severe acute asthma and troublesome wheezing
Year: 2019

Valved holding chamber drug delivery is dependent on breathing pattern and device design
Source: ERJ Open Res, 5 (1) 00158-2018; 10.1183/23120541.00158-2018
Year: 2019



Comparison of two valved holding chambers for the delivery of an HFA-based solution corticosteroid formulation
Source: Eur Respir J 2002; 20: Suppl. 38, 500s
Year: 2002

Impact of inspiratory delay and valved holding chamber (VHC) material on drug delivery
Source: Eur Respir J 2001; 18: Suppl. 33, 494s
Year: 2001

Priming of a non-conducting valved holding chamber (VHC) is formulation dependent and may result in inconsistent medication delivery
Source: Annual Congress 2007 - Miscellaneous pulmonary pharmacology
Year: 2007


In vitro delivery of an HFA-based corticosteroid by pediatric and adult valved holding chambers (VHC): effect of inhalation flow rate
Source: Eur Respir J 2002; 20: Suppl. 38, 500s
Year: 2002

In vitro comparison of the effect of inhalation delay on the variability of the delivered dose from valved holding chambers
Source: Annual Congress 2012 - Assessing and treating childhood asthma and allergy
Year: 2012


In-vitro performance of two valved holding chambers (VHCs)/Spacers for paediatric use tested with facemasks attached is unaffected by routine use and cleaning
Source: Annual Congress 2008 - Wheezing in preschool children
Year: 2008

New anti-static youth valved holding chamber (VHC) can be used out-of-package and deliver β2-agonist medication effectively
Source: Annual Congress 2009 - New aspects of inhalation therapy
Year: 2009


Delivery of medication via a novel non-electrostatic valved holding chamber (VHC) for infant use depends on the number of inhalations
Source: Eur Respir J 2006; 28: Suppl. 50, 713s
Year: 2006

Not all antistatic valved holding chambers have equivalent performance: An example why each valved holding chamber (VHC)-inhaler combination should be considered unique
Source: Annual Congress 2012 - The best of pharmacology treatments of airway diseases: new devices and drugs
Year: 2012


A small volume valved holding chamber (VHC) manufactured from charge dissipative materials has comparable in vitro performance with a large volume non-conducting plastic spacer for both bronchodilator and anti-inflammatory formulations
Source: Eur Respir J 2005; 26: Suppl. 49, 340s
Year: 2005

Evaluation of delivered dose and treatment time of several mesh nebulizers under in vitro simulated use
Source: International Congress 2017 – Inhalers and their use
Year: 2017

Patient centered development of a new valved holding chamber (VHC) designed specifically for on-the-go use
Source: Virtual Congress 2020 – Asthma inhalers: devices and adherence studies
Year: 2020


Breath-by-breath delivered dose comparison from three anti-static valved holding chambers with facemasks under simulated pediatric breathing conditions
Source: Annual Congress 2011 - Treating childhood asthma
Year: 2011

In vitro performance of an improved collapsible holding chamber (CHC) for the delivery of bronchodilators to patients receiving mechanical ventilation
Source: Annual Congress 2011 - Mechanical ventilation and lung injury: new advances
Year: 2011

Medication delivery via infant and child valved holding chambers (VHCs) with facemask is aided with inhalation flow indicator
Source: Annual Congress 2008 - Diagnosing, monitoring and treating respiratory diseases in primary care
Year: 2008


Antistatic valved holding chambers do not necessarily offer similar aerosol delivery performance
Source: Annual Congress 2013 –Early diagnosis and effectiveness of disease management in primary care
Year: 2013


Valved holding chamber (VHC) angle can affect pressurized netered-dose inhaler (pMDI) medication delivery efficiency
Source: International Congress 2018 – Determinants and monitoring of asthma control
Year: 2018




Laboratory assessment of drug delivery of Beclomethasone/Formoterol metered dose inhaler (MDI) with a new valved holding chamber (VHC) designed specifically for 'on-the-go' use.
Source: Virtual Congress 2021 – Therapies for respiratory diseases in primary care and COVID - 19
Year: 2021