Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure

Schermuly R.T., Leuchte H., Ghofrani H.A., Weissmann N., Rose F., Kohstall M., Olschewski H., Schudt C., Grimminger F., Seeger W., Walmrath D.

Source: Eur Respir J 2003; 22: 342-347
Journal Issue: August
Disease area: Pulmonary vascular diseases, Respiratory critical care

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Schermuly R.T., Leuchte H., Ghofrani H.A., Weissmann N., Rose F., Kohstall M., Olschewski H., Schudt C., Grimminger F., Seeger W., Walmrath D.. Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure. Eur Respir J 2003; 22: 342-347

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Combined inhalation of iloprost and the dual selective phosphodiesterase (PDE) inhibitor tolafentrine in a model of acute pulmonary hypertension
Source: Eur Respir J 2001; 18: Suppl. 33, 198s
Year: 2001

The new clinical trials on pharmacological treatment in pulmonary arterial hypertension
Source: Eur Respir J 2002; 20: 1037-1049
Year: 2002



Aerosolized iloprost induces a mild but sustained inhibition of platelet aggregation
Source: Eur Respir J 2002; 19: 518-524
Year: 2002



The effect of bosentan, iloprost, epoprostenol and treprostinil on human monocyte migration
Source: Annual Congress 2009 - Pathobiology of pulmonary vascular diseases
Year: 2009


No interaction of roflumilast, a new, orally active, selective PDE4 inhibitor, with inhaled salbutamol
Source: Eur Respir J 2001; 18: Suppl. 33, 156s
Year: 2001

Aerosolized PGE1, PGI2 and nitroprusside protect against vascular leakage in lung ischaemia-reperfusion
Source: Eur Respir J 2001; 18: 15-22
Year: 2001



Bosentan, epoprostenol and iloprost affect migration of human monocytes in vitro
Source: Annual Congress 2008 - Regulatory mechanisms of cell activation, renewal and recruitment
Year: 2008

The dual PDE3/PDE4 phosphodiesterase inhibitor RPL554 produces more complete bronchodilator responses than the beta2-agonist salbutamol and the anti-muscarinic agent ipratropium bromide, alone and in combination, in guinea-pig isolated trachea
Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis
Year: 2015


Intravenous iloprost for treatment failure of aerosolised iloprost in pulmonary arterial hypertension
Source: Eur Respir J 2002; 20: 339-343
Year: 2002



First-dose bronchodilating effect of phosphodiesterase-4 (PDE-4) inhibition by cilomilast (Ariflo) with or without coadministration of salbutamol and/or ipratropium in COPD patients
Source: Eur Respir J 2001; 18: Suppl. 33, 35s
Year: 2001

Oral administration of a new prostacyclin agonist with thromboxane synthase inhibitory activity improves bleomycin-induced lung fibrosis
Source: Annual Congress 2010 - New insights in the treatment of idiopathic pulmonary fibrosis
Year: 2010


Roflumilast, a new, orally active, selective PDE4 inhibitor, does not interact with inhaled budesonide
Source: Eur Respir J 2001; 18: Suppl. 33, 156s
Year: 2001

PDE 3/4 inhibition prolonges pulmonary vasodilatory response to inhaled iloprost
Source: Eur Respir J 2001; 18: Suppl. 33, 414s
Year: 2001

The selective phosphodiesterase 4 inhibitor, cilomilast, inhibits interleukin-8-induced pulmonary neutrophil accumulation in the rabbit
Source: Eur Respir J 2001; 18: Suppl. 33, 35s
Year: 2001

A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice
Source: Annual Congress 2010 - Experimental approaches in pulmonary fibrosis
Year: 2010

Theeffect of treprostinil, iloprost and bosentan on T-cell migration
Source: Annual Congress 2010 - Pathobiology of pulmonary hypertension
Year: 2010

Effect of phosphodiesterase 4 (PDE-4) inhibitor – rolipram with or without co-administration of dexamethasone on experimental asthma - guinea pig model
Source: Eur Respir J 2004; 24: Suppl. 48, 128s
Year: 2004

Discovery of competitive thromboxane receptor (TP) antagonism by diclofenac in guinea pig airway and vascular tissues
Source: Annual Congress 2007 - Recent advances in airway smooth muscle biology
Year: 2007


Rolipram, a PDE4 inhibitor, but not prednisolone, inhibited pulmonary neutrophilia induced by intratracheal instillation of IL-8 in mice
Source: Eur Respir J 2005; 26: Suppl. 49, 104s
Year: 2005

IL-1β-induced MCP-1 production in human airway smooth muscle cells, modulation by dexamethasone, rolipram, and salbutamol
Source: Eur Respir J 2001; 18: Suppl. 33, 353s
Year: 2001