Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells

Ishii T., Fujishiro M., Masuda M., Goshima Y., Kitamura H., Teramoto S., Matsuse T.

Source: Eur Respir J 2004; 23: 665-670
Journal Issue: May

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Ishii T., Fujishiro M., Masuda M., Goshima Y., Kitamura H., Teramoto S., Matsuse T.. Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells. Eur Respir J 2004; 23: 665-670

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Nadroparin inhibits A549 human adenocarcinoma cell proliferation through down-regulation of cyclin B1 and G2/M phase cell-cycle arrest
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010


Correlation between expression of p53, pRb, mdm2, p21WAF1/CIP1, PCNA, cyclin D1 and apoptotic index (AI) in non-small cell lung cancer (NSCLC) cells
Source: Annual Congress 2006 - Molecular pathology and genetics of lung cancer
Year: 2006


Functional expressions of EGFP/LKB1 and its kinase domain induced apoptosis and enhanced chemosensitivity in lung cancer cell lines
Source: Eur Respir J 2004; 24: Suppl. 48, 5s
Year: 2004

The inhibition of fas-mediated apoptosis of lung alveolar epithelial cells by cyclin dependent kinase inhibitor p21
Source: Eur Respir J 2001; 18: Suppl. 33, 358s
Year: 2001

The effect of compensatory induction of various PTEN mutants against TGFbeta-induced translocation of beta-catenin in lung cancer cells
Source: Annual Congress 2013 –Novel in vitro and animal models to study lung diseases
Year: 2013

Axl receptor tyrosine kinase drives cell cycle re-entry and promotes symmetric cell division of airway basal cells in response to injury
Source: International Congress 2016 – Emerging concepts in lung disease pathogenesis
Year: 2016


GSK-3 inhibition suppresses lung cancer cell survival, metastasis and proliferation through down-regulation the phosphorylation sites of CAP1
Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench
Year: 2017

KPNB1-mediated PD-L1 nuclear translocation promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signalling pathway
Source: Virtual Congress 2020 – Biological mechanisms of lung cancer
Year: 2020

Growth arrest and apoptosis induced by E2F-1 is associated with downregulation of p21 and uncoupling of S-phase and mitosis in NSCLC
Source: Eur Respir J 2001; 18: Suppl. 33, 475s
Year: 2001

SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescence
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013

Counteracting the ET-1 induced pathological cell proliferation by bosentan – nuclear expression of cell cycle inhibitors p21 (waf1) and p27 (kip1) induces G1-arrest in pulmonary artery smooth muscle cells
Source: Annual Congress 2008 - Pulmonary vascular biology
Year: 2008

Triptolide enhances radiosensitivity of lung cancer cells via G2/M arrest and autophage
Source: Virtual Congress 2020 – Biological mechanisms of lung cancer
Year: 2020


Caspase recruitment domain containing protein 9 suppresses non-small cell lung cancer proliferation and invasion via inhibiting MAPK/p38 pathway
Source: Virtual Congress 2020 – Molecular alterations and immunology in lung cancer
Year: 2020

Cell cycle regulation of IPF-derived lung fibroblasts is dependent on RhoA signalling
Source: Eur Respir J 2005; 26: Suppl. 49, 102s
Year: 2005

Blocking VEGF does not induce proapoptotic effects in the NSCLC cell line A549
Source: Annual Congress 2010 - New insights in the pathology of lung cancer
Year: 2010


Involvement of proteasome inhibition and p53 accumulation in epithelial apoptosis of lung injury
Source: Eur Respir J 2005; 26: Suppl. 49, 101s
Year: 2005

Bcl-2 overexpression inhibits apoptotic cell death, but is not sufficient to protect L929 cells from hyperoxia
Source: Eur Respir J 2005; 26: Suppl. 49, 345s
Year: 2005

The effects of TNF-α combined with VP16 on growth and cell cycle of lung cancer cell line and the adhesive molecules
Source: Eur Respir J 2002; 20: Suppl. 38, 73s
Year: 2002

Retinoic acid abrogation of TNF-alpha-induced growth arrest in lung alveolar epithelial cells is linked to p21 (CIP1) downregulation
Source: Eur Respir J 2001; 18: Suppl. 33, 477s
Year: 2001

P2X7 receptor regulates cell survival, inflammation processes and proliferation of lung carcinoma cells
Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease
Year: 2019