Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma

Chaudhuri Rekha, McSharry Charles, Brady Jeffrey, Grierson Christal, Messow C. Martina, Spears Mark, Miele Gino, Nocka Karl, MacNee William, Connell Martin, Murchison John T., Sproule Michael, Hilmi Omar J., Miller Douglas K., Thomson Neil C.

Source: Eur Respir J 2014; 44: 895-904
Journal Issue: October
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Chaudhuri Rekha, McSharry Charles, Brady Jeffrey, Grierson Christal, Messow C. Martina, Spears Mark, Miele Gino, Nocka Karl, MacNee William, Connell Martin, Murchison John T., Sproule Michael, Hilmi Omar J., Miller Douglas K., Thomson Neil C.. Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma. Eur Respir J 2014; 44: 895-904

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Airway pathology in COPD compared to that in smokers with asthma
Source: Annual Congress 2008 - Smokers with asthma versus COPD: differences and similarities
Year: 2008


Cell spectrum and oxidant/anti-oxidant status of induced sputum in smokers with airway obstruction versus smokers without obstruction and nonsmokers
Source: Eur Respir J 2001; 18: Suppl. 33, 92s
Year: 2001

Spontaneous airway obstruction masks FeNO level in patients with asthma but not COPD
Source: Annual Congress 2012 - Exhaled biomarkers in airway diseases
Year: 2012

Induced sputum and airway inflammation in asthma and COPD
Source: Annual Congress 2006 - PG14 - Noninvasive monitoring of asthma inflammation and treatment
Year: 2006

Association of sputum eosinophils with small airway obstruction in cigarette smokers
Source: Eur Respir J 2005; 26: Suppl. 49, 105s
Year: 2005

Sputum eosinophilia vs exhaled NO as markers of airways inflammation in asthma: relationship with asthma control
Source: Eur Respir J 2005; 26: Suppl. 49, 736s
Year: 2005

Subjects in a population study with high levels of FENO have associated eosinophil airway inflammation in BAL
Source: Eur Respir J 2004; 24: Suppl. 48, 469s
Year: 2004

Inflammation of airways and results of 6-MWT at smokers with bronchial asthma.
Source: International Congress 2017 – Smoking and molecular findings
Year: 2017



A low sputum MMP-9 activity/TIMP ratio is associated with CT airway wall thickness in smokers with asthma
Source: Annual Congress 2013 –Systemic and airway biomarkers in respiratory diseases
Year: 2013

Sputum eosinophilia, airway hyperresponsiveness and airway narrowing in young adults with former asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 733s
Year: 2005

Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers
Source: Eur Respir J 2005; 26: 835-845
Year: 2005



Cytokine expression in induced sputum in smokers with asthma or COPD and in healthy smokers
Source: Eur Respir J 2003; 22: Suppl. 45, 392s
Year: 2003

Comparison of Nε-(carboxymethyl)lysine levels and percentage of eosinophils in induced sputum for assessment of small airway involvements in asthma
Source: Annual Congress 2009 - Airway inflammation and asthma control
Year: 2009


Maximal airway response in patients with asthma and cough variant asthma
Source: Annual Congress 2007 - COPD, sarcoidosis, idiopathic pulmonary fibrosis, cystic fibrosis, gastro-oesophageal reflux and cough variant asthma - pathogenesis and differential diagnosis
Year: 2007


Bronchial vascularity in the airways of chronic bronchitis and COPD smokers
Source: Annual Congress 2010 - COPD and asthma: models and human studies
Year: 2010


Neutrophil elastase levels in sputum of patients with different airway diseases: COPD, bronchiectasis and asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 95s
Year: 2002

Airway and systemic inflammation profile in current smokers controls, COPD current smokers and COPD ex-smokers
Source: Annual Congress 2009 - Biomarkers and biology in COPD
Year: 2009


Bronchial biopsies composition in smokers and nonsmokers in COPD exacerbation
Source: Eur Respir J 2004; 24: Suppl. 48, 411s
Year: 2004

Skiers with or without asthma have increased airway diffusion rate of NO from the airways
Source: Virtual Congress 2020 – Epidemiology and understanding of airways diseases in primary care
Year: 2020


Restoring corticosteroid sensitivity in COPD and smokers with asthma
Source: Annual Congress 2008 - Smokers with asthma versus COPD: differences and similarities
Year: 2008