Urokinase plasminogen activation receptor (uPAR) levels correlate with bronchial epithelial barrier integrity

M. Slater, D. Shaw, I. Sayers (Nottingham, United Kingdom)

Source: International Congress 2014 – New studies into pulmonary proteases and antiproteases
Session: New studies into pulmonary proteases and antiproteases
Session type: Oral Presentation
Number: 4854
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Slater, D. Shaw, I. Sayers (Nottingham, United Kingdom). Urokinase plasminogen activation receptor (uPAR) levels correlate with bronchial epithelial barrier integrity. Eur Respir J 2014; 44: Suppl. 58, 4854

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
TNF-a induces cPLA2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Evidence for a novel kit adhesion domain mediating human mast cell adhesion to structural airway cells
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Urokinase plasminogen activator receptor variants drive distinct phenotypes in the bronchial epithelium
Source: International Congress 2015 – Promising novel findings in translational pulmonary research
Year: 2015

TNF alpha promotes coxsackie and adenovirus receptor (CAR) phosphorylation by PKC delta to drive leukocyte transepithelial migration
Source: International Congress 2014 – Cell biology 2014
Year: 2014


Differential expression of uPAR in cultured bronchial epithelial cells from asthma patients
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

S100 proteins induce MUC5AC production in airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Enhanced inflammatory gene expression in bronchial epithelial cells from asthmatic patients: Attenuation by a Brd4 mimic
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014


LATE-BREAKING ABSTRACT: The coagulant factor Xa induces PAR-1 and annexin A2-dependent airway smooth muscle cytokine production and cell proliferation.
Source: International Congress 2014 – COPD: points to ponder
Year: 2014

Human mast cells and type 2 innate lymphoid cells activate gene expression and mucus composition in human bronchial epithelial cells via IL-13
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Inhibition of IRAK4 suppresses chemokine release from human bronchial epithelial cells
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

Expression of CX3CL1 and CX3CR1 in human asthmatic lung in relation to cell survival
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Proprotein convertase 5/6A induces squamous differentiation of airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

The role of chemokine receptors in the aberrant migration of COPD neutrophils
Source: International Congress 2014 – Cell biology 2014
Year: 2014

PCDH1: Localization and cell-adhesion in airway epithelium in asthma
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

IL-4 induced changes in the Wnt signalling of bronchial epithelial cells
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

Interleukin-22 downregulates double-stranded RNA-induced expression of B7-H1/PD-L1 on airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Human lung mast cells alter asthmatic airway epithelial cell function
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


Proteinase-activated receptor-1 and 2 expression in the bronchial epithelium
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

KCa3.1 mediates alphaSMA expression in human lung myofibroblast via the Smad2/3 and TGFbeta1 signalling pathway
Source: International Congress 2014 – Cell biology 2014
Year: 2014

The role of the KCa3.1 channel in the regulation of airway mucus hypersecretion in asthma
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014