Novel oral voltage-gated sodium channel (Nav) inhibitors inhibit capsaicin induced cough in conscious guinea pigs Source: International Congress 2015 – New models for treating airway diseases Year: 2015
Pharmacological profile of a novel, potent and oral TRPA1 antagonist. Characterization in a preclinical model of induced cough Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis Year: 2015
An open-label pilot study of memantine, an N-methyl-D-aspartate receptor antagonist in chronic cough Source: International Congress 2014 – Novel evidence relating to respiratory treatment development Year: 2014
Levosimendan reduces cholinergic bronchoconstriction: The role of KATP channels Source: International Congress 2016 – Lung function and imaging: new findings and new approaches Year: 2016
LATE-BREAKING ABSTRACT: The bitter tastants chloroquine and noscapine relax human bronchial smooth muscle by different effects on intracellular calcium signalling Source: International Congress 2014 – Latest insights in airway diseases Year: 2014
Neurokinin-1 receptor antagonism for the treatment of cough in lung cancer Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action Year: 2016
Safety and efficacy of P2X3 antagonist BAY 1902607 in refractory chronic cough Source: Virtual Congress 2020 – Chronic cough: only symptom or disease? Year: 2020
LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers Source: International Congress 2015 – Hot topics on airway diseases: new horizons in treatment Year: 2015
Effect of the KCa3.1 k+ channels blocker triarylmethane-34 in a murine model of chronic asthma Source: Annual Congress 2009 - COPD and asthma - from the cell to the clinic Year: 2009
LATE-BREAKING ABSTRACT: Antitussive effect of a diphenhydramine-containing multicomponent cough syrup in acute viral cough. Source: International Congress 2014 – Latest insights in airway diseases Year: 2014
Role of TRPA1 and TRPV1 in tussive responses to PGE2 , BK and low pH Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
The effect of leukotrienes and their receptor antagonists on calcium signalling in the cough receptors transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1) Source: Annual Congress 2010 - Models of airways disease Year: 2010
beta2-Agonists block tussive responses in guinea pigs via an atypical cAMP-dependent pathway Source: Eur Respir J 2010; 35: 647-654 Year: 2010
Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors and beyond Source: Eur Respir J, 56 (2) 2001610; 10.1183/13993003.01610-2020 Year: 2020
LATE-BREAKING ABSTRACT: Safety, pharmacokinetics and pharmacodynamics of BI 1060469, a novel oral CRTH2 antagonist Source: International Congress 2016 – Asthma management Year: 2016
Late Breaking Abstract: GRC 17536, a novel, selective TRPA1 antagonist for potential treatment of respiratory disorders Source: Annual Congress 2010 - Animal models of asthma and lung inflammation Year: 2010
A new ultra-potent vanilloid receptor 1 (VR1) antagonist abates capsaicin and citric acid induced cough Source: Eur Respir J 2002; 20: Suppl. 38, 190s Year: 2002
LATE-BREAKING ABSTRACT: Tackling the burden of chronic cough: A dose escalation study of AF-219 Source: International Congress 2016 – Late-breaking topics in airways disease Year: 2016
Inhibition of cough reflex by D2 receptor agonism with Viozan™ (AR-C68397AA) Source: Eur Respir J 2001; 18: Suppl. 33, 32s Year: 2001