Tight junction proteins claudin 3 and 4 in bronchioles and bronchi of COPD and effect of cigarette smoke, slug and twist in vivo and in vitro

H. Merikallio, Y. Soini, A. Manninen, P. Pääkkö, S. Lehtonen, R. Kaarteenaho, T. Harju (Oulu, Kuopio, Finland)

Source: Annual Congress 2013 –COPD: experimental biology
Session: COPD: experimental biology
Session type: Thematic Poster Session
Number: 621
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Merikallio, Y. Soini, A. Manninen, P. Pääkkö, S. Lehtonen, R. Kaarteenaho, T. Harju (Oulu, Kuopio, Finland). Tight junction proteins claudin 3 and 4 in bronchioles and bronchi of COPD and effect of cigarette smoke, slug and twist in vivo and in vitro. Eur Respir J 2013; 42: Suppl. 57, 621

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Role of chronic exposure to cigarette smoke on endoglin/CD105 expression in airway epithelium
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Recurrent cigarette smoke exposure impairs SIRT1 shuttling in bronchial epithelial cells
Source: International Congress 2016 – Translational studies in lung disease
Year: 2016

Cigarette smoke impairs airway epithelial barrier function and cell–cell contact recovery
Source: Eur Respir J 2012; 39: 419-428
Year: 2012



Cigarette smoke induced Muc5AC is regulated by CARM1 in an ex-vivo airway model
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013



Effect of whole cigarette smoke exposure and CCSP on MUC5AC mucin production in primary cultures of human bronchial epithelial cells at air-liquid interface of COPD, smokers and control patients
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Claudins in COPD: Effect of cigarette smoke exposure on claudin expression in vivo and in vitro
Source: Annual Congress 2010 - Novel insights into the pathophysiology of asthma and COPD
Year: 2010

Cigarette smoke augments MUC5AC mucin production via TLR3-EGFR pathway in airway epithelial cells
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013


Cigarette smoke extract induces the release of extracellular vesicles by airway epithelial cells via cellular carbonyl stress
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

Acute effect of cigarette smoke on human bronchial epithelial cell metabolome is reversible by UPF1
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


Cigarette smoke impairs autophagic flux in bronchial epithelial cells
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

Myofibroblast expression in airways and alveoli is affected by smoking and COPD
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013

Epithelial mesenchymal transition (EMT) in small and large airways of smokers; and relation to airflow obstruction
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015

Specific knockdown of versican 1 ameliorated the impairment of elastin deposit in pulmonary fibroblasts co-cultured with cigarette smoke
Source: Annual Congress 2013 –The vulnerable patient and ageing cells
Year: 2013

Cigarette smoke alters the EZH2/DAB2IP expression in bronchial epithelial cells. A risk factor for lung cancer in COPD patients
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016

Cigarette smoke alters primary human bronchial epithelial cell (PBEC) differentiation at air-liquid interface (ALI) and induces expression of CD105 and CD146
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016

LSC - 2020 - Cigarette smoke exposure disrupts the molecular regulation of mitochondrial metabolism in human bronchial and alveolar epithelial cells
Source: Virtual Congress 2020 – Effects of environmental exposures on lung pathology
Year: 2020


Role of chronic exposure to cigarette smoke on Oct-4/CD146 imbalance in human bronchial epithelial cells
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Electrophysiological study of the ENaC function of sheep tracheal epithelium with and without cigarette smoke extract exposure
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Cigarette smoke impairs Sirt1 activity and promotes pro-inflammatory responses in bronchial epithelial cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015