Stimulation of IL-8 release in respiratory cell cultures by increasing IL1-beta concentrations: Effect of budesonide

J. Figueroa, F. Elias, M. Callello, A. Dugour (Buenos Aires, Argentina)

Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Session: Asthma: new mechanisms and markers
Session type: Thematic Poster Session
Number: 578
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. Figueroa, F. Elias, M. Callello, A. Dugour (Buenos Aires, Argentina). Stimulation of IL-8 release in respiratory cell cultures by increasing IL1-beta concentrations: Effect of budesonide. Eur Respir J 2013; 42: Suppl. 57, 578

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Use of interleukin-1beta (IL-1beta) and interleukin-1 receptor antagonist (IL-1Ra) contents in alveolar macrophages for estimation of inflammation activity in patients with different levels of asthma control
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Elevated IL-10 level but not cysteinyl leukotrienes (CysLT) release from leukocytes in vitro correlates with good response to treatment with montelukast in asthmatic patients
Source: International Congress 2014 – Asthma and COPD management
Year: 2014


Enhanced anti-inflammatory gene expression in humans following inhaled budesonide
Source: Annual Congress 2013 –Novel pharmacological findings in the management of respiratory disorders
Year: 2013

Importin-7 knockdown reduces corticosteroid induced glucocorticoid receptor nuclear localisation and suppression of IL-1beta induced CXCL8
Source: Annual Congress 2013 –Novel mechanisms for established drugs for asthma and COPD management
Year: 2013

Importance of levels production of Il-4 in the pathogenesis and formation of the phenotype of asthma
Source: International Congress 2015 – The immunology of allergic airway disease
Year: 2015


Does tumour necrosis factor-alpha (TNF-alpha) induced by lipopolysaccharide have a positive feedback effect on the up-regulation of interleukin-8 (IL-8) messenger RNA by monocytes from COPD patients?
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Cytokine-induced glucocorticoid resistance: Effect on GILZ expression and reversal by formoterol
Source: Annual Congress 2013 –Novel drugs and biomarkers in respiratory medicine
Year: 2013

Differential effect of fluticasone on Poly(I:C) induced TSLP secretion by bronchial epithelial cells from asthmatic children
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

cPLA2alpha inhibitor ASB14780 suppresses airway MMP-9 production and improves respiratory function in cigarette-smoke induced model
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014


Effect of doxofylline on LPS-induced leukocyte migration to the lung
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013

Synergistic effects of p38 MAPK inhibition with a corticosteroid in alveolar macrophages from corticosteroid insensitive asthma patients
Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD
Year: 2013

shRNA suppresses of IL-13 production in vitro
Source: Annual Congress 2013 –Novel in vitro and animal models to study lung diseases
Year: 2013

Effects of dexamethasone and anti-inflammatory drugs on inflammatory cytokines from bronchial epithelial cells of COPD patients
Source: International Congress 2015 – New insights into lung disease pathogenesis
Year: 2015


Therapeutic blockade of IL-4 and 13 signaling with dupilumab (SAR231893/REGN668) inhibits key biomarkers in asthma
Source: Annual Congress 2013 –Treatment of asthma
Year: 2013

Long-term exposure to TNF-alpha and IL-1beta reduces vitamin D-mediated expression of the antimicrobial peptide hCAP18/LL-37 in primary bronchial epithelial cells (PBEC)
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


Ration of IL1beta / IL1-receptor antagonist (RA) in alveolar macrophages of induced sputum of patients with asthma during long-term follow-up
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014


Inhibition of LPS-induced cytokine/chemokine production from human lung macrophages by roflumilast is enabled by autocrine PGE2
Source: Annual Congress 2010 - Macrophages: cell biology and disease-specific characteristics
Year: 2010


Differential effects of simvastatin and dexamethasone on TLR3-induced anti-viral cytokines in asthmatic epithelium
Source: Annual Congress 2013 –Studies of asthma in man
Year: 2013

Late Breaking Abstract - Bedaquiline enhances receptor phagocytosis and decreases IL1b production in human pro-inflammatory macrophages
Source: Virtual Congress 2021 – Immunological and molecular characterisation of tuberculosis disease and infection
Year: 2021


Synergistic anti-inflammatory effects of salmeterol and fluticasone on the release of IL-8 and MCP-1 by human bronchial epithelial cells
Source: Eur Respir J 2003; 22: Suppl. 45, 39s
Year: 2003