N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure Source: Eur Respir J 2005; 25: 797-803 Year: 2005
Effect of p38 MAPK inhibition on corticosteroid suppression of cytokine release in severe asthma Source: Eur Respir J 2010; 35: 750-756 Year: 2010
The pan janus kinase (JAK) inhibitor KN-002 suppresses inflammatory mediator release from severe asthma bronchial epithelial cells. Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science Year: 2021
Inhibition of GM-CSF generation in human alveolar macrophages by reduction of histone acetylation and by dephosphorylation of p38 MAPK and MKK-1 Source: Eur Respir J 2001; 18: Suppl. 33, 475s Year: 2001
Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008
Ceramide-1-phosphate decreases allergic airway inflammation, remodeling and hyperresponsiveness by inhibition of phosphorilation of NF-kappa B, Akt, MAPK p-38 in dendritic cells Source: Annual Congress 2010 - Models of airways disease Year: 2010
Inhibition of p38 mitogen-activated protein kinase has no effect on macrophage phagocytosis of bacteria in patients with COPD Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection Year: 2013
Involvement of protein kinase A (PKA) in the IL-1β induced MCP-1 production in human airway smooth muscle cells Source: Eur Respir J 2001; 18: Suppl. 33, 353s Year: 2001
Effect of PDE4 inhibitors on MAPK activation and IL-8 production on A549 cells following the induction of oxidative stress Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages Source: Eur Respir J 2004; 23: 805-812 Year: 2004
Exposure to LPS induces the upregulation of p38 MAPK in human bronchial epithelium in vivo Source: Eur Respir J 2003; 22: Suppl. 45, 459s Year: 2003
Differential anti-inflammatory effects of budesonide and a p38 MAPK inhibitor AZD7624 on COPD pulmonary cells Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control Year: 2018
Syk is downstream of ICAM-1 and mediates human rhinovirus (HRV) activation of p38 MAP kinase in airway epithelial cells Source: Annual Congress 2006 - Airway epithelial cells in inflammation Year: 2006
P38 MAPK and MMP-9 mediate airway mucus hypersecretion induced by acrolein Source: Annual Congress 2007 - Recent advances in our understanding of the mechanisms of asthma treatment Year: 2007
N-acetylcysteine reduces chemokine release via inhibition of p38 MAPK in human airway smooth muscle cells Source: Eur Respir J 2003; 22: 43-49 Year: 2003
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004
Mitogen-activated protein-kinase modulation of NF-kappaB-induced GM-CSF release from human alveolar macrophages Source: Eur Respir J 2003; 22: Suppl. 45, 392s Year: 2003