The specific free radical scavenger edaravone suppresses bleomycin-induced acute pulmonary injury in rabbits

Y. Ohno, T. Asai, J. Endou, H. Yuhgetsu, M. Sawada, S. Minatoguchi, B. Burin, K. Gotou, H. Fujiwara (Gifu, Japan)

Source: Annual Congress 2007 - Animal and ex vivo models of airway inflammation
Session: Animal and ex vivo models of airway inflammation
Session type: Thematic Poster Session
Number: 888
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Y. Ohno, T. Asai, J. Endou, H. Yuhgetsu, M. Sawada, S. Minatoguchi, B. Burin, K. Gotou, H. Fujiwara (Gifu, Japan). The specific free radical scavenger edaravone suppresses bleomycin-induced acute pulmonary injury in rabbits. Eur Respir J 2007; 30: Suppl. 51, 888

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice
Source: Eur Respir J 2008; 32: 1337-1343
Year: 2008



N-acetyl-L-cysteine modify prostanoids levels in bleomycin-induced lung injury
Source: Eur Respir J 2002; 20: Suppl. 38, 489s
Year: 2002

The role of sulfhydryl compounds in the prevention of acute bleomycin-induced lung injury
Source: Eur Respir J 2002; 20: Suppl. 38, 487s
Year: 2002

Attenuation by oral N-acetylcysteine of bleomycin-induced lung injury in rats
Source: Eur Respir J 2001; 17: 1228-1235
Year: 2001



The thiol antioxidant nacystelyn decreases the pulmonary inflammation caused by endotoxin in a rat model
Source: Eur Respir J 2001; 18: Suppl. 33, 182s
Year: 2001

Creatine supplementation attenuates systemic and pulmonary effects of acute lung injury induced by pulmonary ischemia-reperfusion in rats
Source: Annual Congress 2012 - Lung transplantation: studies in candidates and recipients
Year: 2012


Rho-kinase inhibitor ameliorates bleomycin-induced chronic lung injury in neonatal rats
Source: Annual Congress 2011 - Issues in paediatric and neonatal intensive care
Year: 2011

The effects of erdosteine and N-acetylcysteine treatment following lung injury on the regulation of apoptosis of capillary endothelial cells in the model of experimental pulmonary fibrosis induced by bleomycin
Source: Annual Congress 2008 - Airway cell biology and immunology
Year: 2008

Protective effect of lecithinized superoxide dismutase (PC-SOD) againast elastase-induced pulmonary emphysema in mice
Source: Annual Congress 2011 - Translational models of disease
Year: 2011


Heme scavenging by alpha1-antitrypsin as a potent therapeutic strategy to prevent systemic inflammation and tissue damage after lung transplantation
Source: International Congress 2017 – From donor lung selection and organ preservation to lung transplant outcome
Year: 2017

Angiopoietin-1 variant, COMP-Ang1 attenuates hydrogen peroxide-induced acute lung injury
Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of pulmonary diseases
Year: 2008


Effect of phosphodiesterase-4 inhibitor on the inflammation, oxidative damage and apoptosis in a saline lavage-induced model of acute lung injury
Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control
Year: 2018



Aminophylline treatment alleviated meconium-induced acute lung injury in rabbits
Source: Annual Congress 2007 - Neonatal respiratory disorders: pathogenesis, management and outcomes
Year: 2007


Pioglitazone attenuates endotoxin-induced acute lung injury by reducing neutrophil recruitment
Source: Eur Respir J 2012; 40: 416-423
Year: 2012



Experimental therapy with zinc-ions diminishes oxidant lung injury in rats
Source: Eur Respir J 2006; 28: Suppl. 50, 660s
Year: 2006

Rikkunshito ameliorates bleomycin-induced lung injury in mice
Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Year: 2012

Effects of N-acetylcysteine in lipopolysaccharide-induced acute lung injury in the rat: Treatment after acute lung injury
Source: Annual Congress 2011 - Mechanical ventilation and lung injury: new advances
Year: 2011

Protective effect of Polydexyribonucleotide against lipopolysaccharide-induced acute lung injury in rats
Source: International Congress 2017 – From respiratory muscles to acute respiratory failure
Year: 2017


Protective effects of peroxiredoxin 6 on lipopolysaccharide-induced acute lung injury
Source: Annual Congress 2009 - Crossing the line: alveolo-capillary barrier control in acute lung injury
Year: 2009

Eugenol prevents inflammation but not oxidative stress in diesel-induced acute lung injury
Source: Annual Congress 2010 - Lung morbidity on exposure to various agents
Year: 2010