The dual PDE3/PDE4 phosphodiesterase inhibitor RPL554 produces more complete bronchodilator responses than the beta2-agonist salbutamol and the anti-muscarinic agent ipratropium bromide, alone and in combination, in guinea-pig isolated trachea Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis Year: 2015
The long-acting β2-agonist formoterol re-establishes the anti-proliferative effect of glucocorticoids in asthmatic airway smooth muscle cells (ASMC) Source: Annual Congress 2011 - Understanding disease and drug mechanisms Year: 2011
The inhaled anticholinergic agent, aclidinium bromide, reverses cholinergic-induced bronchoconstriction in guinea pigs with a fast onset of action and a long duration of effect Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD Year: 2008
Budesonide prevents cytokine-induced decrease of the relaxant response to formoterol but not to salmeterol in mouse trachea Source: Annual Congress 2009 - Translational research/biomarkers Year: 2009
Budesonide reverses IL-13–induced airway hyper-responsiveness but has little effect on β2 agonist response in human small airways Source: Annual Congress 2012 - The best of pharmacology treatment for asthma and COPD Year: 2012
Synergistic effects between glycopyrronium bromide and indacaterol on a muscarinic agonist-induced contraction in airway smooth muscle Source: Annual Congress 2012 - The best of pharmacology treatment for asthma and COPD Year: 2012
Synergistic bronchoprotective activity of the long-acting beta 2-agonist olodaterol with tiotropium (long-acting M3 antagonist) and ciclesonide (inhaled steroid) on the ovalbumin-induced bronchoconstriction in anaesthetized guinea pigs Source: Annual Congress 2011 - Understanding disease and drug mechanisms Year: 2011
Rapid inhibitory effects of budesonide and formoterol on bradykinin-induced Ca2+ mobilization in human lung fibroblasts Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Budesonide augments formoterol-induced bronchodilation of human small airways within minutes Source: International Congress 2015 – Safety of and interactions between current treatments for asthma and COPD Year: 2015
Bronchial hypersensitivity and acute bronchodilatory effect of salbutamol on methacholine-induced bronchoconstriction in asthmatics with excessive airway narrowing Source: Eur Respir J 2004; 24: Suppl. 48, 442s Year: 2004
Inhaled roflumilast and tadalafil supress airway reactivity and inflammation in ovalbumin-sensitized guinea pigs Source: International Congress 2016 – Preclinical pharmacology: drug targets and mechanisms of action Year: 2016
Prostacyclin IP receptor activation blocks hyperosmolar-induced bronchoconstriction in isolated human small airways Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action Year: 2016
Protective effect of inhaled iloprost on exercise-induced bronchoconstriction Source: Eur Respir J 2004; 24: Suppl. 48, 443s Year: 2004
Effects of salbutamol enantiomers on equine isolated bronchial airways Source: Annual Congress 2009 - Models of chronic airways disease and therapy Year: 2009
Pharmacological interaction between glycopyrronium bromide and indacaterol fumarate on the human airways tone Source: International Congress 2016 – Preclinical pharmacology: drug targets and mechanisms of action Year: 2016
Compound X – an inhaled β2 agonist with equivalent potency and superior duration of action (DOA)/ therapeutic index (TI) to salmeterol in the anaesthetised dog model of bronchoconstriction Source: Annual Congress 2008 - Novel treatments for respiratory disease Year: 2008
Modulation of cholinergic contractions of airway smooth muscle by cathinone: potential beneficial effects in airway diseases Source: Eur Respir J 2008; 32: 579-584 Year: 2008
Involvement of the BK channels/G proteins processes in the synergistic effects between anticholinergic agents and beta2 -adrenoceptor agonists in airway smooth muscle Source: Annual Congress 2013 –Novel mechanisms for established drugs for asthma and COPD management Year: 2013
The influence of epithelium on the effect of isoprenaline incubation in responsiveness of guinea-pig trachea to b-adrenergic agonist and antagonist Source: Annual Congress 2007 - Airway regulation, provocation and monitoring - III Year: 2007
Antagonism by reproterol of adenosine-mediated tension responses in isolated guinea pig trachea Source: Eur Respir J 2003; 22: Suppl. 45, 106s Year: 2003