Replicative senescence of lung fibroblasts after exposure to hydrogen peroxide or cigarette smoke extract

R. A. Jörres, A. Kronseder, S. Uhlmann, O. Holz, L. Welker, H. Hessel, D. Branscheid, H. Magnussen, D. Nowak (Munich, Großhansdorf, Germany)

Source: Annual Congress 2005 - From molecules to patients: mechanisms of lung injury, fibrosis and cancer
Session: From molecules to patients: mechanisms of lung injury, fibrosis and cancer
Session type: Thematic Poster Session
Number: 728
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. A. Jörres, A. Kronseder, S. Uhlmann, O. Holz, L. Welker, H. Hessel, D. Branscheid, H. Magnussen, D. Nowak (Munich, Großhansdorf, Germany). Replicative senescence of lung fibroblasts after exposure to hydrogen peroxide or cigarette smoke extract. Eur Respir J 2005; 26: Suppl. 49, 728

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Repeated exposure to cigarette smoke extract (CSE) in primary human lung fibroblasts – effects on proliferation rate
Source: Eur Respir J 2006; 28: Suppl. 50, 635s
Year: 2006

Cigarette smoke extract induces barrier changes and senescence in primary bronchial epithelial cells
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Z-Alpha-1-antitrypsin and cigarette smoke extract impair apoptosis in human bronchial epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 797s
Year: 2006

COPD fibroblasts are more responsive to cigarette smoke exposure
Source: Annual Congress 2009 - Mechanisms of pulmonary inflammation and fibrosis
Year: 2009

Cigarette smoke exposure in mice leads to a loss of reversible cysteine oxidations PSSG and PSNO in lung
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011

Mitochondria are essential in cigarette smoke induced ROS generation
Source: Annual Congress 2008 - Airway cell biology
Year: 2008


Role of highly reactive aldehydes in cigarette smoke induced airway inflammation
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011


Effects of aminophylline on apoptosis induced by cigarette smoke extract (CSE) in MRC-5 cells
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Cigarette smoke extract (CSE) induces clusterin expression in human lung fibroblasts
Source: Eur Respir J 2004; 24: Suppl. 48, 105s
Year: 2004

Cigarette smoke irreversibly binds to glutathione in airway epithelial cells
Source: Annual Congress 2007 - Molecular pathogenesis: focus on COPD and asthma
Year: 2007


Cigarette smoke exposure disrupts the molecular regulation of mitochondrial metabolism in human bronchial and alveolar epithelial cells
Source: ERS Lung Science Conference 2020
Year: 2020

Antioxidant properties of mate tea in mouse lung exposed to cigarette smoke
Source: Annual Congress 2007 - Molecular pathogenesis: focus on COPD and asthma
Year: 2007


Effect of cigarette smoke extract (CSE) on the differentiation and function of adipocytes
Source: Eur Respir J 2006; 28: Suppl. 50, 585s
Year: 2006

Cigarette smoke extract induces the release of extracellular vesicles by airway epithelial cells via cellular carbonyl stress
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

Cigarette smoke and diesel particles repress functional responses in lung epithelial progenitors
Source: International Congress 2019 – Involvement of the environment and inflammation in pulmonary remodelling
Year: 2019

Early transcriptional responses of bronchial epithelial cells following exposure to whole cigarette smoke
Source: Virtual Congress 2021 – Early manifestations of chronic respiratory disease: zooming in at the epithelial barrier
Year: 2021



Impact of PM2.5 on cigarette smoke exposed airway epithelial cells and lung tissues
Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects
Year: 2017

Cigarette smoke extract and diesel particles result in the production of pro-inflammatory molecules from human primary lung fibroblast strains and pulmonary epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 413s
Year: 2001

The protective effects of thymoquinone on lung damage developed by cigarette smoke
Source: International Congress 2017 – From the bench: therapeutic approaches in COPD and emphysema
Year: 2017


Cigarette smoke exposure alters the inflammatory reaction of airway epithelium
Source: Eur Respir J 2003; 22: Suppl. 45, 561s
Year: 2003