Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

Austin E. D., Cogan J. D., West J. D., Hedges L. K., Hamid R., Dawson E. P., Wheeler L. A., Parl F. F., Loyd J. E., Phillips J. A. III

Source: Eur Respir J 2009; 34: 1093-1099
Journal Issue: November
Disease area: Pulmonary vascular diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Austin E. D., Cogan J. D., West J. D., Hedges L. K., Hamid R., Dawson E. P., Wheeler L. A., Parl F. F., Loyd J. E., Phillips J. A. III. Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females. Eur Respir J 2009; 34: 1093-1099

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives
Source: Eur Respir J 2002; 20: 518-523
Year: 2002



Mutations in the bone morphogenic protein receptor 2 promoter in heritable pulmonary arterial hypertension
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018



Pulmonary arterial hypertension associated with fenfluramine exposure: report of 109 cases
Source: Eur Respir J 2008; 31: 343-348
Year: 2008



Targeting bone morphogenic protein receptor 2 (BMPR2) signalling to treat pulmonary arterial hypertension
Source: Eur Respir J, 50 (3) 1701370; 10.1183/13993003.01370-2017
Year: 2017



Genetics of pulmonary hypertension: from bench to bedside
Source: Eur Respir J 2002; 20: 741-749
Year: 2002



Inhibiting oestrogen signalling in pulmonary arterial hypertension: sex, drugs and research
Source: Eur Respir J, 50 (2) 1700983; 10.1183/13993003.00983-2017
Year: 2017



BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease
Source: Eur Respir J 2004; 24: 371-374
Year: 2004



Estrogen receptor alpha gene polymorphisms and primary pulmonary hypertension
Source: Eur Respir J 2005; 26: Suppl. 49, 352s
Year: 2005

Expression of fetal genes in pulmonary arterial hypertension
Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms
Year: 2005


Primary pulmonary hypertension after amfepramone (diethylpropion) with BMPR2 mutation
Source: Eur Respir J 2003; 22: 560-562
Year: 2003



Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension
Source: Eur Respir J, 53 (6) 1801524; 10.1183/13993003.01524-2018
Year: 2019



Pathobiology of pulmonary arterial hypertension and right ventricular failure
Source: Eur Respir J 2012; 40: 1555-1565
Year: 2012



First identification of Krüppel-like factor 2 mutation in heritable pulmonary arterial hypertension
Source: International Congress 2017 – Current molecular and genetic understanding of lung diseases
Year: 2017


Association of VDR, COL1A1 and CALCR genes polymorphisms with susceptibility to steroid osteoporosis in patients with idiopathic pulmonary fibrosis
Source: Annual Congress 2010 - Clinical aspects in pulmonary fibrosis
Year: 2010


Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension
Source: Eur Respir J 2009; 34: 1100-1110
Year: 2009



Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects
Source: Eur Respir J, 50 (2) 1602337; 10.1183/13993003.02337-2016
Year: 2017



BMPR2 mutation status influences bronchial vascular changes in pulmonary arterial hypertension
Source: Eur Respir J 2016; 48: 1668-1681
Year: 2016



BMPR2 mutations and iron metabolism in pulmonary arterial hypertension patients
Source: Virtual Congress 2021 – Pathogenesis and pathophysiology of pulmonary hypertension
Year: 2021


Clinical characteristics, hemodynamics and survival in idiopathic and familial pulmonary arterial hypertension with germline BMPR2 mutation
Source: Eur Respir J 2007; 30: Suppl. 51, 250s
Year: 2007