Protective effect of cysteinyl leukotriene receptor antagonist montelukast in bleomycin induced pulmonary fibrosis

N. Topaloglu, T. Lacin, E. Bas, C. Ataizi, B. Ceyhan (Istanbul, Turkey)

Source: Annual Congress 2007 - Considerations in the therapeutic approach of interstitial lung disease: oxidative stress and inflammation
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. Topaloglu, T. Lacin, E. Bas, C. Ataizi, B. Ceyhan (Istanbul, Turkey). Protective effect of cysteinyl leukotriene receptor antagonist montelukast in bleomycin induced pulmonary fibrosis. Eur Respir J 2007; 30: Suppl. 51, 780

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Protective effect of leukotriene receptor antagonist montelukast in bleomycin induced pulmonary fibrosis
Source: Eur Respir J 2006; 28: Suppl. 50, 669s
Year: 2006

Effect of cysteinyl leukotriene receptor antagonist on airway wall remodeling
Source: Eur Respir J 2002; 20: Suppl. 38, 304s
Year: 2002

The CysLT1 receptor antagonist montelukast blocks bronchoconstriction induced by inhaled leukotriene E4 in subjects with asthma
Source: International Congress 2015 – The immunology of allergic airway disease
Year: 2015

Inhaled corticosteroids and leukotriene receptor antagonists induce protection against adenosine 5‘monophosphate induced bronchospasm in a synergic fashion
Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring
Year: 2007


The CysLT1 receptor antagonist montelukast inhibits mast cell activation induced by inhaled leukotriene E4 in subjects with asthma
Source: International Congress 2016 – Clinical and molecular studies in asthma
Year: 2016


Role of leukotriene receptor antagonist on TGF-β1 and Smad signalling in bleomycin induced pulmonary fibrosis
Source: Annual Congress 2009 - A wide spectrum of idiopathic pulmonary fibrosis
Year: 2009


Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in the airway remodeling induced by chronic airway inflammation in guinea pigs
Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II
Year: 2008

Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis
Source: Eur Respir J 2009; 34: 1444-1451
Year: 2009



Inhibitory effect of PGE2 receptor subtype, EP4, in bleomycin-induced pulmonary fibrosis
Source: Annual Congress 2007 - Mechanisms of injury and repair in fibrotic, idiopathic or infectious lung disease
Year: 2007


Anti-inflammatory effects of histamine H1-receptor antagonist and leukotriene CysLT1-receptor antagonist in patients with atopic asthma maintained on inhaled corticosteroids
Source: Eur Respir J 2004; 24: Suppl. 48, 221s
Year: 2004

The effects of a cysteinyl leukotriene receptor antagonist, pranlukast, on dendritic cell chemoattractants in the airways of subjects with asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 132s
Year: 2004

Abrogation of bleomycin induced inflammation and lung fibrosis by angiotensin AT1 receptor antagonist. Relevance of PGE-2 modulation
Source: Eur Respir J 2005; 26: Suppl. 49, 82s
Year: 2005

Late Breaking Abstract: Anti-fibrogenic effects of the endothelin-A receptor antagonist ambrisentan in a mouse pulmonary fibrosis model
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Effect of AVE5883, a dual NK1/NK2 receptor antagonist, on airway responsiveness to neurokinin A in asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 219s
Year: 2004

Effects of leukotriene receptor antagonists on airway mucus secretion
Source: Eur Respir J 2001; 18: Suppl. 33, 245s
Year: 2001

Leukotriene receptor antagonist versus corticotherapy on airways responsiveness in ovalbumin sensitized rats
Source: Eur Respir J 2003; 22: Suppl. 45, 478s
Year: 2003

Inhibition of eosinophil migration by montelukast, a cysteinyl leukotriene receptor antagonist, through down regulation of plasmin activity
Source: Eur Respir J 2004; 24: Suppl. 48, 36s
Year: 2004

Montelukast inhibits bronchoconstriction and gas exchange defects induced by leukotriene D4 challenge in asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 308s
Year: 2002

A role of prostaglandin D2 receptor, CRTH2, on bleomycin-induced pulmonary fibrosis
Source: Annual Congress 2008 - Understanding allergic airway inflammation with the help of animal models
Year: 2008

Oral administration of a new prostacyclin agonist with thromboxane synthase inhibitory activity improves bleomycin-induced lung fibrosis
Source: Annual Congress 2010 - New insights in the treatment of idiopathic pulmonary fibrosis
Year: 2010