Inhibition of phosphodiesterase 4 enhances lung alveolarisation in neonatal mice exposed to hyperoxia Source: Eur Respir J 2009; 33: 861-870 Year: 2009
The PDE4 inhibitor roflumilast reduced bleomycin-induced pulmonary fibrotic and vascular remodeling in mice in vivo Source: Annual Congress 2008 - Animal models of pulmonary fibrosis: mechanisms and therapies Year: 2008
Rho-kinase inhibitor ameliorates bleomycin-induced chronic lung injury in neonatal rats Source: Annual Congress 2011 - Issues in paediatric and neonatal intensive care Year: 2011
The selective phosphodiesterase 4 inhibitor, cilomilast, inhibits interleukin-8-induced pulmonary neutrophil accumulation in the rabbit Source: Eur Respir J 2001; 18: Suppl. 33, 35s Year: 2001
Effect of induced hypothermia on alveolar macrophage function in endotoxin-challenged rats Source: Eur Respir J 2002; 20: Suppl. 38, 485s Year: 2002
The novel phosphodiesterase 4 inhibitor CI-1044 inhibits in vitro LPS-induced TNFα production in whole blood of COPD patients Source: Eur Respir J 2001; 18: Suppl. 33, 34s Year: 2001
Roflumilast N-oxide, a PDE4 inhibitor, curbs bleomycin-induced lung fibroblast activation in vitro Source: Annual Congress 2011 - Airway smooth muscle cells and fibroblasts: cell biology Year: 2011
The selective PDE4-inhibitor AWD 12-281 inhibits LPS-induced neutrophilia in domestic pig lung, an animal model of COPD: comparison with steroids Source: Eur Respir J 2001; 18: Suppl. 33, 160s Year: 2001
Inhibition by roflumilast vs cilomilast of pulmonary leukocyte accumulation and TNFα release in a rat model of LPS-induced pulmonary neutrophilia Source: Eur Respir J 2003; 22: Suppl. 45, 107s Year: 2003
Efficacy of the PDE4 inhibitor, BAY 19-8004, in a smoke-induced model of pulmonary inflammation in the guinea pig Source: Eur Respir J 2001; 18: Suppl. 33, 36s Year: 2001
Phosphodiesterase-4 inhibition attenuates pulmonary inflammation in neonatal lung injury Source: Eur Respir J 2008; 31: 633-644 Year: 2008
Simvastatin attenuates cigarette-smoke- induced emphysema and promotion of alveolar epithelial cell proliferation in rats Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in chronic and acute airway diseases Year: 2010
Early changes in COX-2 and iNOS expression in cultured fibroblasts from bleomycin-treated rats Source: Eur Respir J 2002; 20: Suppl. 38, 479s Year: 2002
Resveratrol attenuates hypoxic pulmonary vascular remodeling in simulated high altitude-exposed rats: potential role of Hif-1α/NOX4/ROS inhibition Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments Year: 2012
Inhibition of the Arp2/3 complex inhibits lung myofibroblast differentiation in vitro and attenuates bleomycin-induced pulmonary fibrosis in mice Source: International Congress 2019 – Extracellular matrix formation and remodelling in physiology and disease Year: 2019
Phosphodiesterase expression profiling in chronic hyperoxia induced lung injury in newborn mice Source: Annual Congress 2006 - Advances in diagnosis and treatment of pulmonary diseases in children Year: 2006
PDE4 inhibition prevents corticosteroid-resistant lung inflammation induced by cigarette smoke exposure in mice Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury Year: 2009
Relaxin potentiates ß2-adrenoceptor mediated bronchodilation in precision-cut lung slices (PCLS) from mouse models of airway inflammation and fibrosis, and in human airways Source: International Congress 2019 – Advances in asthma pharmacology Year: 2019
cPLA2alpha inhibitor ASB14780 suppresses airway MMP-9 production and improves respiratory function in cigarette-smoke induced model Source: International Congress 2014 – Animal models in respiratory drug development Year: 2014
The PDE4 inhibitor roflumilast N-oxide partly reversed TGFß1-induced changes in collagen I and E-cadherin expression in human airway epithelial cells Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD Year: 2008