Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages Source: Eur Respir J 2004; 23: 805-812 Year: 2004
Cigarette smoke extract (CSE) promotes acetylcholine (ACh) mediated inflammation and oxidative stress by PEBP1/Raf-mediated MEK and ERK pathway in human bronchial epithelial cells Source: International Congress 2015 – New data on established treatments for asthma and COPD Year: 2015
Cigarette smoke exposure disrupts VEGF signalling through the kinase insert-domain receptor (KDR) in rat lungs Source: Eur Respir J 2004; 24: Suppl. 48, 30s Year: 2004
Epidermal growth factor receptor (EGFR) overexpression in human bronchial epithelial cells amplifies IL-8 release provoked by cigarette smoke and bacterial surrogates Source: Eur Respir J 2005; 26: Suppl. 49, 441s Year: 2005
Mitogen-activated protein kinase (MAPK) is involved in tight junction (TJ) disruption in a human bronchial epithelial cell line (Beas-2B) induced by cigarette smoke (CS) Source: Annual Congress 2007 - Mechanisms and new treatments of COPD Year: 2007
Effects of glucocorticoids on activation of extracellular signal-regulated kinases (ERK) in human pulmonary endothelial cells Source: Eur Respir J 2001; 18: Suppl. 33, 160s Year: 2001
17-beclomethasone monopropionate or inhibition of MAPK p38 signalling abolish IL-8 release stimulated by cigarette smoke extract or acrolein in normal human airway smooth muscle cells Source: Annual Congress 2010 - Airway smooth muscle cells Year: 2010
Cigarette smoke extract induces a multi-phase cell cycle arrest in normal human lung fibroblasts. Ivolvement of MAPK pathway Source: Eur Respir J 2004; 24: Suppl. 48, 106s Year: 2004
ERK MAP kinase is upregulated in pulmonary emphysema and mediates MMP-1 induction by cigarette smoke Source: Eur Respir J 2004; 24: Suppl. 48, 437s Year: 2004
Cigarette smoke induces mitochondrial dysfunction via PKCd-p66Shc signaling pathway in human bronchial epithelial cells Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium Year: 2018
Cigarette smoke extract induces barrier changes and senescence in primary bronchial epithelial cells Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms Year: 2019
Activation of MAPKs in bronchial-epithelial NCI-H292 cells co-treated with extracellular Hsp70 and bacterial components or cigarette smoke extract Source: International Congress 2018 – COPD: immune regulation and therapeutic targets Year: 2018
Tobacco smoke induces muc5AC expression in normal bronchial epithelial cells trough activation of the NADPH system in a mechanism involving EGF-R activation Source: Annual Congress 2009 - Translational models of lung disease Year: 2009
Cigarette smoke upregulates IL-8/CXCL8 expression by augmenting mRNA stability via p38 MAPK/MK2 signalling in normal human pulmonary cells Source: Annual Congress 2012 - Basic and translational studies in COPD Year: 2012
Cigarette smoke and TGF-β1 increase p21waf1/cip1 expression in alveolar epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 97s Year: 2002
Cigarette smoke extract (CSE) induces clusterin expression in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 105s Year: 2004
Z-Alpha-1-antitrypsin and cigarette smoke extract impair apoptosis in human bronchial epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 797s Year: 2006
YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Cigarette smoke extract, affecting choline acetyltransferase and muscarinic receptor M3 expression, induces MUC5AC in NCI-H292 cell line Source: Annual Congress 2013 –The pulmonary epithelium: recent developments Year: 2013
α,β-unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through MAP kinases activation Source: Annual Congress 2009 - Airway inflammation and host defence Year: 2009