Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD

Hukkanen J., Pelkonen O., Raunio H.

Source: Eur Respir J 2001; 18: 122S-126S
Journal Issue: July 2001 - Suppl. 32

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Hukkanen J., Pelkonen O., Raunio H.. Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD. Eur Respir J 2001; 18: 122S-126S

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The perpetrator potential of sitaxentan based on its ability to inhibit human cytochrome P450 (CYP) enzymes
Source: Annual Congress 2008 - Pulmonary vascular disease and other pulmonary conditions: miscellaneous
Year: 2008


Association analysis between polymorphisms in the cytochrome P450 2J2, 2S1 and UDP-glucuronosyltransferase 2B7 genes with occupational chronic bronchitis
Source: Annual Congress 2010 - Genetics of obstruction
Year: 2010

Cytochrome P450 1A1 polymorphism and severity of COPD
Source: Eur Respir J 2002; 20: Suppl. 38, 212s
Year: 2002

Epoxyeicosatrienoates are the dominant eicosanoids in human lungs upon microbial challenge
Source: Eur Respir J 2010; 36: 1088-1098
Year: 2010



Effects of aryl hydrocarbon receptor and cytochrome P450 1A1 polymorphisms on childhood lung function and asthma
Source: Eur Respir J 2007; 30: Suppl. 51, 296s
Year: 2007

Absence of inhibitory effect of levocetirizine on the metabolism of human cytochrome P450 model substrates
Source: Eur Respir J 2005; 26: Suppl. 49, 136s
Year: 2005

The victim potential of sitaxentan: metabolism by human CYP450 enzymes
Source: Annual Congress 2008 - Pulmonary vascular disease and other pulmonary conditions: miscellaneous
Year: 2008


Genetic polymorphisms in the cytochromes P450, microsomal epoxide hydrolase and glutathione S-transferase M1, T1 and P1 genes and their relationship to relapsing bronchitis and pneumonia in case of children
Source: Eur Respir J 2005; 26: Suppl. 49, 167s
Year: 2005

Cytochrome P450 2A5 methylation and gene expression profile is organ-specific and affected by maternal smoking during pregnancy
Source: International Congress 2018 – Functional genomics and COPD: new challenges
Year: 2018


The perpetrator potential of sitaxentan: human CYP enzyme induction
Source: Annual Congress 2008 - Pulmonary vascular disease and other pulmonary conditions: miscellaneous
Year: 2008


Cytochrome P450 pharmacogenetics: a possible predictor of pulmonary drug induced toxicity?
Source: Eur Respir J 2007; 30: Suppl. 51, 488s
Year: 2007

Interactions between roflumilast and cytochrome P450 inducers and inhibitors: Overview of existing studies
Source: Annual Congress 2010 - Management of airway disease
Year: 2010

Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD
Source: Eur Respir J 2008; 32: 931-937
Year: 2008



Genetic association study of CYP1A1 polymorphisms identifies risk haplotypes in nonsmall cell lung cancer
Source: Eur Respir J 2010; 35: 152-159
Year: 2010



Interaction of GSTMI null variant and cytochrome P-450 type 1A1 Ile462Val polymorphism and susceptibility to COPD
Source: Eur Respir J 2002; 20: Suppl. 38, 94s
Year: 2002

Common variants of the microsomal epoxide hydrolase and glutamate-cysteine ligase in European populations are not associated with susceptibility to COPD
Source: Annual Congress 2008 - Advances in functional genomics of neoplastic and non-neoplastic lung diseases
Year: 2008


Polymorphisms for epoxide hydrolase, glutathione transferase and genetic susceptibility to COPD
Source: Virtual Congress 2020 – Monitoring of inflammation in remodelling
Year: 2020


Effect of genetic polymorphisms of some cytokines and xenobiotic-metabolizing enzymes on the lung function in patients with COPD
Source: Annual Congress 2012 - Recent progress in mechanisms and diagnostics of COPD and asthma
Year: 2012


Association of polymorphisms of cytochrome P450 genes (CYP1A1 and CYP1A2) with chronic obstructive pulmonary disease in Tatars and Russians from Bashkortostan
Source: Eur Respir J 2007; 30: Suppl. 51, 21s
Year: 2007

Cytochrome CYP2C9 and vitamin K epoxide reductase gene polymorphisms in patients with pulmonary embolism treated with warfarin
Source: Annual Congress 2007 - The role of gene polymorphisms in pulmonary disease susceptibility
Year: 2007