Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture

Holz O., Zuhlke I., Jaksztat E., Muller K.C., Welker L., Nakashima M., Diemel K.D., Branscheid D., Magnussen H., Jorres R.A.

Source: Eur Respir J 2004; 24 : 575-579
Journal Issue: October
Disease area: Airway diseases

Congress or journal article abstractPDF journal article, handout or slidesFull text journal article

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Holz O., Zuhlke I., Jaksztat E., Muller K.C., Welker L., Nakashima M., Diemel K.D., Branscheid D., Magnussen H., Jorres R.A.. Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture. Eur Respir J 2004; 24 : 575-579

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Primary human airway epithelial cells inhibit proliferation of lung fibroblasts via transforming growth factor-β
Source: Annual Congress 2007 - Acute and chronic lung injury and its repair: novel molecular insight
Year: 2007


Cigarette smoke inhibits lung fibroblast proliferation by translational mechanisms
Source: Eur Respir J 2012; 39: 705-711
Year: 2012



Mesenchymal stem cells isolated from fibrotic human lung tissue inhibit collagen expression by lung fibroblasts
Source: International Congress 2016 – ILD: from the bench to the bedside
Year: 2016

The secretome of induced pluripotent stem cells (iPSC) modulates macrophage phenotype in the fibrotic lung
Source: International Congress 2015 – Pulmonary fibrosis: mechanisms of disease
Year: 2015

Altered phenotype of COPD primary fibroblasts from airway and alveolar tissues: proliferation and apoptosis.
Source: International Congress 2019 – Research and innovation in airway diseases
Year: 2019

Fibroblast growth factor 9 (FGF9) modulates mesothelial cells plasticity to decrease differentiation and migration in vitro
Source: International Congress 2016 – Common mechanisms in lung development and fibrosis
Year: 2016

Lung fibroblasts from COPD patients presented a reduced response to TGF-β1 for proliferation and elastin synthesis
Source: Annual Congress 2011 - Molecular: pathology of infectious and inflammatory lung disease
Year: 2011

Fibroblast growth factor 9 (FGF9) modulates the phenotype of control and fibrotic human lung fibroblasts in vitro
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

LSC Abstract – Activation of FGF9 and 18 in idiopathic pulmonary fibrosis promote survival and migration and inhibit myofibroblast differentiation of human lung fibroblasts
Source: International Congress 2016 – Common mechanisms in lung development and fibrosis
Year: 2016

Differences of in vitro proliferation between skin and lung parenchymal fibroblasts in patients with emphysema
Source: Eur Respir J 2006; 28: Suppl. 50, 796s
Year: 2006

Telomerase activity in bleomycin-induced epithelial cell apoptosis and lung fibrosis
Source: Eur Respir J 2007; 30: 205-213
Year: 2007



Apoptotic cell instillation after bleomycin attenuates lung injury through hepatocyte growth factor induction
Source: Eur Respir J 2012; 40: 424-435
Year: 2012



Primary airway epithelial cell culture from lung transplant recipients
Source: Eur Respir J 2005; 26: 1080-1085
Year: 2005



Rescue of murine silica-induced lung injury and fibrosis by human embryonic stem cells
Source: Eur Respir J 2012; 39: 446-457
Year: 2012



KL-6, a human MUC1 mucin, promotes proliferation and survival of lung fibroblasts
Source: Eur Respir J 2006; 28: Suppl. 50, 340s
Year: 2006

Targetingpyruvate kinase M2 isoform inhibits proliferation of human lung fibroblasts
Source: International Congress 2016 – ILD: from the bench to the bedside
Year: 2016

The effects of hypoxia on the expression of MMP-2, MMP-9 in human lung adenocarcinoma A549 cells
Source: International Congress 2014 – Biology and pathology of thoracic tumours
Year: 2014

The enhancement of Stanniocalcin-1 (STC1) secretion increases the ability of mesenchymal stem cells (MSCs) to reduce bleomycin-induced lung fibrosis in a mouse model through inhibition of endoplasmic reticulum stress (ER-stress)/TGFbeta1 pathway
Source: International Congress 2014 – ILDs 1
Year: 2014


Human lung mast cells alter asthmatic airway epithelial cell function
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013