Inhaled IL-4/IL-13 antagonist decreases response to antigen challenge in atopic asthmatic subjects

D. Wilbraham, E. Burmeister Getz, M. Longphre, S. Wenzel, R. Fuller (London, United Kingdom; Berkeley, CA, Pittsburgh, PA, United States Of America)

Source: Annual Congress 2007 - New drugs for asthma
Session: New drugs for asthma
Session type: Oral Presentation
Number: 2959
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. Wilbraham, E. Burmeister Getz, M. Longphre, S. Wenzel, R. Fuller (London, United Kingdom; Berkeley, CA, Pittsburgh, PA, United States Of America). Inhaled IL-4/IL-13 antagonist decreases response to antigen challenge in atopic asthmatic subjects. Eur Respir J 2007; 30: Suppl. 51, 2959

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Inhibition of the inhaled allergen challenge response by the CRTH2 antagonist OC000459 in patients with asthma
Source: Annual Congress 2010 - Novel anti-inflammatory agents for airway disease
Year: 2010

Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459
Source: Eur Respir J 2013; 41: 46-52
Year: 2013



The effect of a leukotriene antagonist, pranlukast, on allergen-induced airway responses and circulating dendritic cells in subjects with atopic asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 414s
Year: 2003

Omalizumab protects against allergen-induced bronchoconstriction in patients with allergic (IgE-mediated) asthma and high baseline IgE levels
Source: Annual Congress 2009 - Severe asthma and its treatment
Year: 2009


Chemokine and cytokine production in the airway from atopic asthmatics after segmental allergen challenge
Source: Eur Respir J 2003; 22: Suppl. 45, 378s
Year: 2003

The inhaled PDE4 inhibitor GSK256066 significantly inhibits airway responses following allergen challenge in asthmatics
Source: Annual Congress 2008 - Novel treatments for respiratory disease
Year: 2008


Inhaled synthetic surfactant abolishes the early allergen-induced response in asthma
Source: Eur Respir J 2003; 21: 1046-1049
Year: 2003



Montelukast as add-on therapy to β-agonists and late airway response
Source: Eur Respir J 2007; 30: 56-61
Year: 2007



Effect of an inhaled alpha4-antagonist on the allergen-induced late asthmatic response in patients with mild asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 135s
Year: 2005

A monoclonal antibody to IL-1B attenuates the late asthmatic response to antigen challenge in patients with mild asthma
Source: Annual Congress 2006 - Novel treatments for asthma
Year: 2006


Expression of CCR3 in bronchial biopsies after allergen challenge in subjects with atopic asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 5s
Year: 2002

Protective effect of inhaled iloprost on specific bronchial challenge in aspirin-sensitive asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 471s
Year: 2002

Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis
Source: Annual Congress 2011 - T-cell subsets
Year: 2011


The inhaled PDE4 inhibitor UK-500,001 does not significantly inhibit airway responses to allergen and histamine
Source: Annual Congress 2007 - New drugs for asthma
Year: 2007


Relationships of mannitol challenge to methacholine challenge and inflammatory markers in asthmatics receiving inhaled corticosteroids
Source: Annual Congress 2012 - Bronchial challenge as a biomarker of respiratory disease
Year: 2012



Tolerance to the protective effect of salmeterol on allergen challenge in mild untreated asthmatics and in moderate asthmatics on inhaled corticosteroid treatment
Source: Eur Respir J 2001; 18: Suppl. 33, 103s
Year: 2001

The effect of smoking on the response to nasal antigen challenge in patients with allergic rhinitis
Source: Eur Respir J 2002; 20: Suppl. 38, 217s
Year: 2002

Does sputum eosinophil counts predict the response to inhaled corticosteroids in terms of methacholine bronchial responsiveness in steroid naive asthmatics?
Source: Eur Respir J 2001; 18: Suppl. 33, 336s
Year: 2001

Anti-IL17 treatment controls airway asthmatic responses exacerbated by LPS
Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology
Year: 2017