Dupilumab efficacy in children with uncontrolled, moderate-to-severe asthma with and without an allergic phenotype

N. Papadopoulos (Manchester, United Kingdom), S. Szefler (Aurora, CO, United States of America), L. Bacharier (Nashville, TN, United States of America), J. Maspero (Buenos Aires, Argentina), C. Domingo (Barcelona, Spain), N. Daizadeh (Cambridge, MA, United States of America), D. Lederer (Tarrytown, NY, United States of America), M. Hardin (Cambridge, MA, United States of America), J. Jacob-Nara (Cambridge, MA, United States of America), Y. Deniz (Tarrytown, NY, United States of America), R. Gall (Tarrytown, NY, United States of America), B. Ortiz (Tarrytown, NY, United States of America), M. Djandji (Cambridge, MA, United States of America), P. Rowe (Bridgewater, NJ, United States of America)

Source: Virtual Congress 2021 – Advances in childhood asthma: biologics, biomarkers and infections
Session: Advances in childhood asthma: biologics, biomarkers and infections
Session type: Oral Presentation
Number: 2568

Congress or journal article abstractWebcastSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. Papadopoulos (Manchester, United Kingdom), S. Szefler (Aurora, CO, United States of America), L. Bacharier (Nashville, TN, United States of America), J. Maspero (Buenos Aires, Argentina), C. Domingo (Barcelona, Spain), N. Daizadeh (Cambridge, MA, United States of America), D. Lederer (Tarrytown, NY, United States of America), M. Hardin (Cambridge, MA, United States of America), J. Jacob-Nara (Cambridge, MA, United States of America), Y. Deniz (Tarrytown, NY, United States of America), R. Gall (Tarrytown, NY, United States of America), B. Ortiz (Tarrytown, NY, United States of America), M. Djandji (Cambridge, MA, United States of America), P. Rowe (Bridgewater, NJ, United States of America). Dupilumab efficacy in children with uncontrolled, moderate-to-severe asthma with and without an allergic phenotype. 2568

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Dupilumab improves lung function and reduces severe exacerbations in uncontrolled persistent asthma patients with ongoing allergic rhinitis
Source: International Congress 2017 – Asthma and allergy: from the bench to the bedside
Year: 2017


The impact of targeted therapy in children with uncontrolled allergic persistent severe asthma and nasal polyps
Source: International Congress 2017 – Paediatric asthma: therapies and comorbidities
Year: 2017

Dupilumab improves patient-reported outcomes in uncontrolled persistent asthma patients with ongoing allergic rhinitis
Source: International Congress 2017 – Asthma and allergy: from the bench to the bedside
Year: 2017


IL-33 in patients with severe uncontrolled allergic asthma
Source: International Congress 2017 – "Alarming" immunological patterns in asthma
Year: 2017


Omalizumab in children with severe persistent allergic asthma
Source: Annual Congress 2010 - Managing asthma and allergic disease in children
Year: 2010

Omalizumab treatment reduces asthma exacerbations in children with moderate or severe persistent asthma
Source: International Congress 2017 – Paediatric asthma: treatment modalities and behavioural issues
Year: 2017

Add-on omalizumab therapy reduces clinically significant and severe asthma exacerbations, and improves FEV1 in patients with severe persistent allergic asthma irrespective of age
Source: Eur Respir J 2005; 26: Suppl. 49, 48s
Year: 2005

Omalizumab is effective in patients with severe persistent allergic asthma in a real-life setting irrespective of age
Source: Annual Congress 2009 - Towards improving asthma control
Year: 2009


Omalizumab therapy reduces asthma exacerbations in children with severe allergic (IgE-mediated) asthma irrespective of lung function at baseline
Source: Annual Congress 2009 - Difficult asthma in children: diagnostic and therapeutic challenges
Year: 2009

Evaluating the efficacy of omalizumab in severe persistent asthma patients
Source: International Congress 2017 – Evolution or revolution in the treatment of asthma and allergies
Year: 2017

Efficacy of tezepelumab in adolescents with severe, uncontrolled asthma
Source: Virtual Congress 2021 – Asthma treatment: clinical and translational science
Year: 2021



Immunotherapy in severe asthma
Source: ERS webinar 2021: Immunotherapy in severe asthma
Year: 2021


A randomized controlled study of omalizumab in children with moderate-to-severe persistent allergic asthma
Source: Annual Congress 2008 - Drug therapy and assessment of control in childhood asthma
Year: 2008


Distribution of biomarkers in severe asthma and severe uncontrolled asthma
Source: Virtual Congress 2021 – Pearls in asthma and respiratory burden research
Year: 2021



Prediction of the risk of future exacerbations in patients with severe persistent allergic asthma
Source: Annual Congress 2005 - Severe asthma: perception and management
Year: 2005


Dupilumab improves lung function in patients with uncontrolled, moderate-to-severe asthma
Source: ERJ Open Res, 6 (1) 00204-2019; 10.1183/23120541.00204-2019
Year: 2020



Real-life effectiveness of omalizumab in patients with severe persistent allergic asthma: the PERSIST study
Source: Annual Congress 2009 - Towards improving asthma control
Year: 2009


Efficacy of Omalizumab in adult and pediatric severe allergic asthma according to presence of multiple allergic comorbidities: evidence from the STELLAIR study.
Source: International Congress 2019 – Understanding, monitoring and targeting severe asthma
Year: 2019

Anti-IgE therapy with omalizumab decreases exacerbations in patients with poorly controlled moderate-to-severe allergic asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 203s
Year: 2003

Omalizumab (Xolair®) reduces exacerbations in patients with moderate-to-severe persistent allergic asthma independent of former smoking status
Source: Annual Congress 2008 - Improving asthma and anti-allergic therapy
Year: 2008