Estrogen and progestin induce the migration of pulmonary artery smooth muscle cells with the contractile phenotype via different mechanisms

W. Hu (Shanghai, China), S. Li (Shanghai, China), D. Liu (Shanghai, China)

Source: Virtual Congress 2021 – Pathogenesis and pathophysiology of pulmonary hypertension
Session: Pathogenesis and pathophysiology of pulmonary hypertension
Session type: E-poster
Number: 595

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
W. Hu (Shanghai, China), S. Li (Shanghai, China), D. Liu (Shanghai, China). Estrogen and progestin induce the migration of pulmonary artery smooth muscle cells with the contractile phenotype via different mechanisms. 595

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: possible mechanisms
Source: Eur Respir J 2004; 24: Suppl. 48, 561s
Year: 2004

Mir-17 modulates smooth muscle cell markers, apoptosis and BMPR-II levels in human pulmonary artery smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Investigating redox sensitive sex differences in serotonin-induced proliferation and migration in rat pulmonary artery smooth muscle cells.
Source: International Congress 2017 – Experimental PH
Year: 2017

miR 16 modulates human pulmonary artery smooth muscle cell phenotype
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and cell biology
Year: 2012

Proliferative hypoxic response of pulmonary artery smooth muscle cells: the fibroblasts role
Source: Eur Respir J 2007; 30: Suppl. 51, 510s
Year: 2007

Sildenafil modulates PDGF and Angiotensin II induced migration and proliferation in human pulmonary artery smooth muscle cells (PA-SMC)
Source: Eur Respir J 2002; 20: Suppl. 38, 227s
Year: 2002

Endothelin-1 downregulates BMP signaling in pulmonary artery smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: clinical PAH, registries and treatments
Year: 2012

Dexamethasone induces anti-remodelling effects in rat pulmonary arterial smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and cell biology
Year: 2012


Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells - role of hypoxia-inducible transcription factors
Source: Eur Respir J 2001; 18: Suppl. 33, 159s
Year: 2001

Targeting CCR2 and CCR5 to inhibit macrophage/pulmonary artery smooth muscle cells cross-talk in pulmonary hypertension
Source: International Congress 2018 – Experimental research in pulmonary hypertension
Year: 2018

Increased expression of endothelinB receptors in the pulmonary arterial smooth muscle cells of fawn-hooded rat
Source: Eur Respir J 2001; 18: Suppl. 33, 416s
Year: 2001

Effect of endothelin-1 and bosentan on gene expressions in the cultured pulmonary artery smooth muscle cells
Source: Annual Congress 2010 - Pulmonary vascular diseases
Year: 2010

Wnt5a down-regulated hypoxia-induced pulmonary arterial smooth muscle cell proliferation by inhibition of β-catenin
Source: Annual Congress 2010 - Pathobiology of pulmonary hypertension
Year: 2010


Bosentan stimulates the expression of cell cycle inhibitor p27(kip1) in pulmonary artery smooth muscle cells (PASMC)
Source: Annual Congress 2007 - Animal and ex vivo models of airway inflammation
Year: 2007


Role of endothelial and smooth muscle cells in vascular wall remodeling of large pulmonary arteries in patients with CTEPH
Source: Annual Congress 2007 - Venous thromboembolic disease
Year: 2007


Increased p130Cas activity induces smooth muscle cell proliferation and migration in idiopathic pulmonary arterial hypertension
Source: Annual Congress 2011 - Experimental pulmonary hypertension
Year: 2011


LSC - 2018 - Pulmonary vascular remodeling mediated by ADORA2B in pulmonary artery smooth muscle cells
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018



Fractalkine-induced smooth muscle cell proliferation in pulmonary hypertension
Source: Eur Respir J 2007; 29: 937-943
Year: 2007



CCR2/CCR5-mediated macrophage–smooth muscle cell crosstalk in pulmonary hypertension
Source: Eur Respir J, 54 (4) 1802308; 10.1183/13993003.02308-2018
Year: 2019



Caspase-1 triggers smooth muscle cell proliferation in hypoxic pulmonary hypertension
Source: International Congress 2019 – Pulmonary hypertension: novelties from the bench
Year: 2019