PP115 – COL4A3 degradation predicts anti-IgE response in severe asthma Source: ERS Lung Science Conference 2021 Year: 2021
Elevated type I collagen degradation predicts persistent asthma in children Source: Virtual Congress 2020 – Novel mechanisms and management of paediatric asthma Year: 2020
Polymorphisms in the type IV collagen alpha3 gene and the risk of COPD Source: Eur Respir J 2008; 32: 35-41 Year: 2008
Type 1 inflammatory endotype relates to low compliance, lung fibrosis, and severe complications in COVID-19 Source: Virtual Congress 2021 – Acute COVID - 19 Year: 2021
Airway gene expression identifies subtypes of Type 2 inflammation in severe asthma Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes Year: 2020
Expression of type 1 and type 2 cytokines in central airways of smokers with chronic bronchitis Source: Eur Respir J 2001; 18: Suppl. 33, 74s Year: 2001
Alveolar type 2 cell dysfunction from expression of a surfactant protein C (SFTPC) mutation drives a fibrotic lung phenotype in mice Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis Year: 2017
COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy Source: Eur Respir J, 58 (6) 2003969; 10.1183/13993003.03969-2020 Year: 2021
HDAC6 inhibition and deletion reduce COPD symptoms in mice and human airway epithelia Source: Virtual Congress 2020 – Elucidating the mechanisms underlying lung repair and exploring therapeutic strategies in vitro Year: 2020
Evidence of early abnormal airways’ inflammation in children with type 1 diabetes Source: Virtual Congress 2021 – Paediatric allergic asthma: novel therapeutics and monitoring approaches Year: 2021
Rhinovirus (RV)-induction of IL-15 in macrophages is dependent on type I IFNs, is deficient in asthma and related to exacerbation severity Source: Annual Congress 2010 - Mechanisms of respiratory infections Year: 2010
Parameters of sIgE and sIgG4-autoAbs to lung elastin, collagen type III and myosin in bronchial asthma in association with chronic infection. Source: International Congress 2019 – Understanding the mechanisms underlying airway diseases Year: 2019
The effects of endogenous and exogenous vitamin D on the rate of mature elastin degradation in COPD patients Source: International Congress 2016 – New signalling pathways in COPD Year: 2016
Benralizumab restored expression of key molecules involved in steroid-resistance in patients with severe asthma Source: Virtual Congress 2020 – Asthma pharmacology: clinical trials and mechanistic insights Year: 2020
Increased expression of SARS-CoV-2 (Covid-19) adhesion sites on type II pneumocytes, small airway epithelium, and alveolar macrophages in smokers and patients with COPD Source: Virtual Congress 2021 – Mechanistic pathways in chronic and new lung diseases Year: 2021
Collagen and elastin turnover increase at COPD exacerbation irrespectively its etiology Source: Virtual Congress 2020 – New biomarkers for management of obstructive diseases Year: 2020
Regulation, cell-specific expression and metabolism of factor VII activating protease (FSAP) in lungs from patients with acute respiratory distress syndrome (ARDS) and idiopathic pulmonary fibrosis (IPF) Source: Eur Respir J 2006; 28: Suppl. 50, 823s Year: 2006
Type II conventional dendritic cells of asthmatic patients with frequent exacerbations have an altered phenotype and frequency Source: Eur Respir J, 55 (6) 1900859; 10.1183/13993003.00859-2019 Year: 2020
Late Breaking Abstract - Type 2 biomarker expression (FeNO and blood eosinophils) is higher in severe adult-onset than in severe early-onset asthma Source: Virtual Congress 2021 – Pearls in immunology, outcome studies and clinical trials in asthma, alpha-1 antitrypsin deficiency and COPD Year: 2021
Prevalence of alpha1-antitrypsin deficiency and its influence on lung function decline in patients with severe asthma Source: Virtual Congress 2020 – Advances in asthma treatment Year: 2020