Sputum neutrophil elastase in bronchiectasis: a Southern European cohort study

Andrea Gramegna, Stefano Aliberti, Oriol Sibila, Carlotta Di Francesco, Giovanni Sotgiu, Lidia Perea, Leonardo Terranova, Martina Oriano, Tommaso Pilocane, Laura Saderi, James D. Chalmers, Paola Marchisio, Francesco Blasi

Source: Eur Respir J, 56 (6) 2001702; 10.1183/13993003.01702-2020
Journal Issue: December
Disease area: Airway diseases, Respiratory infections

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Andrea Gramegna, Stefano Aliberti, Oriol Sibila, Carlotta Di Francesco, Giovanni Sotgiu, Lidia Perea, Leonardo Terranova, Martina Oriano, Tommaso Pilocane, Laura Saderi, James D. Chalmers, Paola Marchisio, Francesco Blasi. Sputum neutrophil elastase in bronchiectasis: a Southern European cohort study. Eur Respir J, 56 (6) 2001702; 10.1183/13993003.01702-2020

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Neutrophil elastase is correlated with disease severity in a cohort from Southern Europe
Source: Virtual Congress 2020 – Biomarkers and characterisation of immune response in respiratory infection
Year: 2020

Neutrophil elastase levels in sputum of patients with different airway diseases: COPD, bronchiectasis and asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 95s
Year: 2002

Sputum neutrophil elastase and inhaled antibiotic response in bronchiectasis: a post-hoc analysis of the ORBIT-4 trial
Source: Virtual Congress 2021 – Bronchiectasis heterogeneity: assessing the endotypes
Year: 2021



Neutrophil elastase and IL-8 assessment in patients with COPD and asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 61s
Year: 2005

Conduct of a biomarker study in bronchiectasis patients: Correlation of neutrophil elastase activity and inflammatory load in induced sputum
Source: International Congress 2014 – Systemic and airway biomarkers
Year: 2014

Characterisation of eosinophilic bronchiectasis: A European multicohort study
Source: Virtual Congress 2021 – Bronchiectasis heterogeneity: assessing the endotypes
Year: 2021



Cell counts in severe asthma; concordance of sputum and BAL in Wessex Severe Asthma Cohort
Source: International Congress 2017 – Monitoring novel biomarkers in asthma
Year: 2017




Changes in sputum bacterial density in people with bronchiectasis: BRONCH UK Study data
Source: Virtual Congress 2021 – Bronchiectasis heterogeneity: assessing the endotypes
Year: 2021



Inflammatory cytokine levels in serum and bronchoalveolar lavage fluid and gene polymorphism in young adult patients with bronchiectasis
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Chronic eosinophilic pneumonia: clinical study, analysis of BAL, tryptase assay
Source: Eur Respir J 2003; 22: Suppl. 45, 177s
Year: 2003

Neutrophil to lymphocyte ratio and severity of COPD : prospective study
Source: Virtual Congress 2021 – New insights into the airway immunology of lung disease
Year: 2021


Predictors of sputum and BAL eosinophilia in the Wessex Severe Asthma Cohort
Source: International Congress 2017 – Monitoring asthma control
Year: 2017


Sputum gene signature comparison study between U-BIOPRED and Australia asthma cohorts
Source: International Congress 2019 – Crosstalk in chronic pulmonary diseases
Year: 2019


Neutrophils in bronchial mucosa, sputum and blood after administration of the CXCR2-antagonist AZD5069 - An explorative study in neutrophilic asthma
Source: International Congress 2016 – Novel mechanisms and treatment modalities in asthma
Year: 2016

Comparison of different techniques to evaluate active neutrophil elastase in sputum of bronchiectasis and cystic fibrosis patients
Source: International Congress 2019 – Complex respiratory infections in clinical practice
Year: 2019

The value of bacterial culture in patients with suspected lung cancer evaluated by bronchoscopy: A prospective study of 155 patients
Source: International Congress 2014 – Cells, biofilms and biomarkers in respiratory infections
Year: 2014

Heterogeneous impact of sputum supernatant on neutrophil phagocytosis in bronchiectasis
Source: International Congress 2018 – Bronchiectasis: phenotypes, endotypes and new therapies
Year: 2018



Levels of proteinase 3 and neutrophil elastase in plasma, BAL and biopsies in COPD
Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies
Year: 2020


Viral prevalence in stable bronchiectasis: analysis of the Cohort of Asian and Matched European Bronchiectasis (CAMEB)
Source: International Congress 2019 – Phenotypes and endotypes of bronchiectasis
Year: 2019

Monitoring sputum eosinophils in mucosal inflammation and remodelling: a pilot study
Source: Eur Respir J 2010; 35: 48-53
Year: 2010