Source: Virtual Congress 2020 – Chronic cough: only symptom or disease?
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
M. Wortley (London, United Kingdom), S. Bonvini (Gothenburg, Sweden), J. Adcock (Gothenburg, Sweden), E. Dubuis (London, United Kingdom), S. Maher (London, United Kingdom), R. Penn (Philadelphia, United States of America), M. Belvisi (Gothenburg, Sweden), M. Birrell (Gothenburg, Sweden). EPAC drives the anti-tussive effect of EP4 receptors on airway sensory nerves. 4562

Member's Comments

No comment yet.

Related content which might interest you: EP2 & EP4 receptor agonists inhibit the airway sensory nerves that cause cough, a potential protective control that is lost in human smokers and a pre-clinical COPD model Source: International Congress 2017 – Novel mechanisms and treatments for COPD Year: 2017 Different alcohols activate airway sensory nerves by a vanilloid receptor 1 (TRPV1) dependent mechanism Source: Eur Respir J 2003; 22: Suppl. 45, 415s Year: 2003 Potentiation effect of insulin on M3 muscarinic receptor agonist induced airway smooth muscle contraction Source: International Congress 2019 – Airway inflammation: pharmacological mechanisms and novel targets Year: 2019 Modulatory role of tachykinin NK1 receptor in cholinergic contraction of mouse trachea Source: Eur Respir J 2003; 21: 3-10 Year: 2003 One component of the antigen-induced contraction of the guinea-pig trachea is mediated by serotonin acting on 5-HT2A receptors Source: Eur Respir J 2007; 30: Suppl. 51, 620s Year: 2007 TRPM3, P2X2 and P2X3 expression patterns in single airway sensory nerves Source: International Congress 2017 – Novel studies on bronchodilators and cough Year: 2017 Interaction of the glutamatergic and nitrergic signaling system in the airway hyperreactivity Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD Year: 2012 TRPM3: A regulator of airway sensory nerves and respiratory reflexes Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action Year: 2016 Cholinergic muscarinic receptors and airway remodelling in severe asthma Source: International Congress 2018 – Studies on the mechanisms underlying airway disease Year: 2018 Muscarinic receptor dependent contraction of small airways from both rats and humans Source: Eur Respir J 2006; 28: Suppl. 50, 432s Year: 2006 Effect of muscarinic receptors inhibition on cytokine release and inflammatory cells infiltration in the airway of cat as an animal model for COPD Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD Year: 2012 Characterisation of TRPA1 activation on sensory nerves Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control Year: 2018 Toll-like receptor stimulation induces airway hyperresponsiveness to bradykinin, an effect mediated by JNK and NF-κB signaling pathways Source: Eur Respir J 2005; 26: Suppl. 49, 732s Year: 2005 Insulin acutely potentiates M3 muscarinic receptor function in rat and human airway smooth muscle Source: International Congress 2017 – Therapeutic approaches in lung disease Year: 2017 Anti-tussive effects of FAAH inhibition: The role of endocannabinoids and downstream signalling pathways in the inhibition of vagal sensory nerve activation Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis Year: 2015 Increased relaxation of immature airways to beta-2 agonists is related to the attenuated expression of postjunctional smooth muscle muscarinic M2 receptors Source: Annual Congress 2004 - Understanding the complexity of how airways are regulated Year: 2004 Toll-like receptors mediating anti-viral responses cause direct and indirect activation of airway smooth muscle Source: Eur Respir J 2005; 26: Suppl. 49, 345s Year: 2005 Role of muscarinic receptors in airway inflammation and remodelling Source: International Congress 2015 – Respiratory research in the Netherlands Year: 2015 The purinergic receptor P2Y2 mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation Source: Annual Congress 2010 - Asthma: basic science and clinical studies Year: 2010 Optogenetic activation of mouse airway parasympathetic neurons to provoke bronchoconstriction Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma Year: 2019