Effect of muscarinic receptors inhibition on cytokine release and inflammatory cells infiltration in the airway of cat as an animal model for COPD Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD Year: 2012
A novel receptor antagonist, c-027, inhibits airway contraction in human and murine models of allergen, independent of inflammatory mediator release Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma Year: 2009
Extracellular ATP triggers and maintains airway inflammation in human and murine models of asthma by activating dendritic cells Source: Annual Congress 2008 - New mechanisms in the pathogenesis of asthma and its response to treatment Year: 2008
ILC2 cells from severe allergic and eosinophilic asthma demonstrate increased expression of TSLP receptor (TSLPR) and enhanced proliferative capacity. Source: Virtual Congress 2021 – New insight into the immunology of allergies, asthma and COPD: from mouse to man Year: 2021
A fully dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a murine model of asthma Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
Inhaled PPAR-r agonist inhibit the airway inflammation in murine model of acute and chronic asthma Source: Eur Respir J 2007; 30: Suppl. 51, 24s Year: 2007
The Cys-LT1 receptor antagonist, pranlukast, attenuates allergen-induced increase in airway eosinophils and bone marrow derived eosinophil/basophil progenitors in subjects with atopic asthma Source: Eur Respir J 2003; 22: Suppl. 45, 349s Year: 2003
Generation and activation of myeloid derived suppressor cells using prostaglandin E2 and EP receptor agonists in vitro Source: International Congress 2019 – Advances in asthma pharmacology Year: 2019
Suppression of allergic airway inflammation in a mouse model of asthma by exogenous mesenchymal stem cells Source: Annual Congress 2010 - Animal models of asthma and lung inflammation Year: 2010
A dual role of IL-6 signalling and STAT-3 activation on airway inflammation versus airway hyperresponsiveness in a murine model of asthma Source: Eur Respir J 2002; 20: Suppl. 38, 568s Year: 2002
Over-expression of SIGIRR attenuates TLR 4,5,9-mediated immune responses in human airway epithelial cells Source: Annual Congress 2009 - Mechanisms of infection: what's new? Year: 2009
Increased expression of Lipocalin2 suppresses allergen-induced airway disease in mice Source: Annual Congress 2008 - Novel mechanisms and targets of molecular pulmonary pathology Year: 2008
Disruption of CD44 variant 6 abolished bronchial hyperresponsiveness, inflammation and mast cell myositis in a murine model of asthma Source: Eur Respir J 2006; 28: Suppl. 50, 217s Year: 2006
EP2 & EP4 receptor agonists inhibit the airway sensory nerves that cause cough, a potential protective control that is lost in human smokers and a pre-clinical COPD model Source: International Congress 2017 – Novel mechanisms and treatments for COPD Year: 2017
Concomitant exposure to nicotine and endotoxin in vitro induces murine airway hyperreactivity possibly via nicotine-induced upregulation of toll-like receptors Source: Annual Congress 2011 - New mechanisms in airway disease Year: 2011
Decreased Smad7 expression in the airways of a mouse model of chronic asthma Source: Annual Congress 2004 - Animal models of allergic airway disease Year: 2004
Characterization of the Toll-IL-1 pathway gene profile in an in-vitro model of chronic airway inflammation Source: Annual Congress 2007 - New treatments for asthma and COPD - experimental evidence Year: 2007
The activation of transient receptor potential melastatin 8 (TRPM8) receptors of bronchial epithelial cells induces airway inflammation in bronchial asthma Source: International Congress 2016 – Studies in airway cell biology Year: 2016
TD-0903, an inhaled JAK inhibitor in development for COVID-19, blocks ARDS-relevant hyperinflammation and lung injury in primary human immune and airway epithelial cells Source: Virtual Congress 2021 – Emerging respiratory diseases: state-of-the-art studies of SARS-CoV-2 infection Year: 2021
Upregulated expression of interleukin-33 and alternative activation of macrophages in a model of an acute exacerbation of asthma Source: Annual Congress 2011 - Asthma: basic science and clinical studies Year: 2011