Let-7 promotes airway remodeling via regulation of IL-6 in chronic obstruction pulmonary disease

T. Bian (Wuxi, China), T. Di (Wuxi, China)

Source: Virtual Congress 2020 – Respiratory homeostasis and structural changes in disease
Session: Respiratory homeostasis and structural changes in disease
Session type: E-poster session
Number: 1890
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
T. Bian (Wuxi, China), T. Di (Wuxi, China). Let-7 promotes airway remodeling via regulation of IL-6 in chronic obstruction pulmonary disease. 1890

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IL-33 blockade prevents exacerbations in a model of chronic airway inflammation by blunting persistent inflammation and remodeling
Source: International Congress 2019 – Advances in asthma pharmacology
Year: 2019

Inflammatory cell microlocalisation and airway dysfunction: cause and effect?
Source: Eur Respir J 2007; 30: 1043-1056
Year: 2007



COPD is associated with reduced pulmonary interstitial expression of pentraxin-3
Source: Eur Respir J 2012; 39: 830-838
Year: 2012



Airway epithelial cell P2Y6R-Expression is up-regulated during acute and chronic allergic inflammation and contributes via modulating of CXC8 and IL-6 secretion to development of airway remodelling
Source: Annual Congress 2010 - Pre-clinical models of airways disease
Year: 2010



The dysregulation of E-cadherin contributes to pulmonary emphysema
Source: International Congress 2017 – Insight into the pathogenesis of emphysema and pneumonia
Year: 2017

Suppressed pulmonary expression of leptin in lipopolysaccharide-induced acute and chronic lung inflammation
Source: Annual Congress 2006 - Novel pathogenic aspects of acute lung injury and acute respiratory distress syndrome (ARDS)
Year: 2006


Neurokinins contribute to vascular remodelling in a model of chronic pulmonary allergic inflammation
Source: Eur Respir J 2006; 28: Suppl. 50, 760s
Year: 2006

Osteopontin exacerbates airway hyperresponsiveness and lung remodeling in chronic asthma
Source: Annual Congress 2008 - Basic science in asthma and COPD
Year: 2008

IL-36? – a key mediator of neutrophilic inflammation in chronic obstructive pulmonary disease
Source: Virtual Congress 2021 – New insights into the airway immunology of lung disease
Year: 2021


Cigarette smoke-induced pulmonary inflammation, but not airway wall remodeling, is attenuated in CCR5 deficient mice
Source: Annual Congress 2007 - The best of airway epithelial cells
Year: 2007



The role of small-airway inflammation and remodeling in asthma
Source: Annual Congress 2013 –Small airways in asthma: from physiologic measures to clinical relevance
Year: 2013


Airway inflammation in COPD: physiological outcome measures and induced sputum
Source: Eur Respir J 2003; 21: 19S-28S
Year: 2003



Proto-oncogenes expression in airway remodelling in asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 159s
Year: 2001

Osteopontin blockade prevents fibrosis in a murine chronic model of allergic airway disease
Source: Eur Respir J 2007; 30: Suppl. 51, 60s
Year: 2007

MiR-320d as a regulator of airway inflammation in COPD
Source: ERS Lung Science Conference 2020
Year: 2020

Pattern of airway inflammation and remodeling in mild chronic obstructive pulmonary disease
Source: Annual Congress 2010 - COPD: treatment and monitoring
Year: 2010

IL-33 blockade impacts mediators of persistence and exacerbation of chronic airway inflammation.
Source: International Congress 2018 – Novel drug targets for asthma and COPD
Year: 2018



Epigenetic-like regulation of signalling proteins in chronic obstructive pulmonary disease
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019


The role of small airways in obstructive airway diseases
Source: Eur Respir Rev 2011; 20: 23-33
Year: 2011



Effects of physical stress on lung mechanics, distal airway eosinophilic and lymphocytic inflammation, IL-13 expression and extracellular matrix remodeling in guinea pigs with chronic pulmonary inflammation
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009