Association between cyclooxygenase inhibitor use and efficacy of immunotherapy: a retrospective study

O. Kanai (Kyoto, Japan), K. Fujita (Kyoto, Japan), M. Okamura (Kyoto, Japan), K. Horimoto (Kyoto, Japan), M. Hashimoto (Kyoto, Japan), K. Nakatani (Kyoto, Japan), S. Sawai (Kyoto, Japan), T. Mio (Kyoto, Japan)

Source: Virtual Congress 2020 – Molecular alterations and immunology in lung cancer
Session: Molecular alterations and immunology in lung cancer
Session type: E-poster session
Number: 1658
Disease area: Thoracic oncology

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
O. Kanai (Kyoto, Japan), K. Fujita (Kyoto, Japan), M. Okamura (Kyoto, Japan), K. Horimoto (Kyoto, Japan), M. Hashimoto (Kyoto, Japan), K. Nakatani (Kyoto, Japan), S. Sawai (Kyoto, Japan), T. Mio (Kyoto, Japan). Association between cyclooxygenase inhibitor use and efficacy of immunotherapy: a retrospective study. 1658

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The novel elastase inhibitor BAY 85-8501: First-in-man study to evaluate safety, tolerability and pharmacokinetics in healthy male subjects
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014


Roflumilast, a selective phosphodiesterase 4 inhibitor, shows efficacy and safety in the long-term treatment of asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 203s
Year: 2003

Association between antacid proton pump inhibitors and histamine 2 receptor antagonists) and incidence of lung cancer: a population-based cohort analysis
Source: Virtual Congress 2021 – Epidemiology and burden of tuberculosis and other lung diseases
Year: 2021

Pharmacological profile and efficacy of GLPG1690, a novel ATX inhibitor for COPD treatment
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015


Efficacy and safety of four doses of CHF6001, a novel inhaled phosphodiesterase-4 inhibitor (PDE4i), in patients with moderate-to-severe COPD
Source: International Congress 2019 – COPD clinical trials: new molecules and novel insights
Year: 2019



Tolerance to COX-2 inhibitors in patients intolerant to aspirin: challenge mandatory
Source: Eur Respir J 2003; 22: Suppl. 45, 547s
Year: 2003

Time on therapy and concomitant medication use of mepolizumab in Canada: a retrospective cohort study
Source: ERJ Open Res, 7 (1) 00778-2020; 10.1183/23120541.00778-2020
Year: 2021



Favorable human safety, pharmacokinetics and pharmacodynamics of the autotaxin inhibitor GLPG1690, a potential new treatment in COPD
Source: International Congress 2015 – Advances in the future treatment of COPD
Year: 2015



Roles of PI3k pan-inhibitors and PI3k-d inhibitors in allergic lung inflammation: systematic review and a meta-analysis
Source: Virtual Congress 2020 – Management of allergy, asthma and COPD
Year: 2020


Safety, tolerability and pharmacokinetics of CHF 6001, a novel selective inhaled PDE4 inhibitor, in healthy volunteers
Source: International Congress 2016 – Preclinical pharmacology: drug targets and mechanisms of action
Year: 2016


Safety, tolerability and pharmacokinetics of a new inhaled once-daily phosphodiesterase (PDE) 4 inhibitor in healthy volunteers
Source: Annual Congress 2013 –Novel drugs and biomarkers in respiratory medicine
Year: 2013

A systematic review of the efficacy of proton pump inhibitors on refractory adult asthma.
Source: International Congress 2017 – Clinical points to ponder in asthma
Year: 2017

The novel selective PDE4 inhibitor roflumilast: early onset of efficacy in asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 203s
Year: 2003

The efficacy and safety of adjunctive corticosteroids in the treatment of tuberculous pleurisyA systematic review and meta-analysis
Source: International Congress 2017 – TB: diagnosis, severity and practical management
Year: 2017

Late Breaking Abstract: A randomised, placebo controlled trial of 6 weeks‘ treatment with a novel oral p38 inhibitor in patients with COPD
Source: Annual Congress 2010 - COPD: management
Year: 2010

The novel elastase inhibitor BAY 85-8501: Bioavailability and Food effect study to evaluate pharmacokinetics of tablet formulations
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014


Nonclinical safety profiles of DS-1515, a novel oral PI3Kd inhibitor.
Source: International Congress 2018 – Basic pharmacology
Year: 2018


SPARTA: Efficacy and safety assessment of two regimens of alpha1-proteinase inhibitor in emphysema due to alpha1-antitrypsin deficiency
Source: Annual Congress 2013 –New clinical trials of asthma and COPD drugs
Year: 2013


Biomarker measurement in asthma patients receiving biologic therapy: a real-world retrospective study
Source: International Congress 2018 – Eosinophils in airway disease
Year: 2018




Suppressive effect of novel phosphodiesterase4 (PDE4) inhibitor ONO-6126 on TNF-α release was increased after repeated oral administration in healthy Japanese subjects
Source: Annual Congress 2003 - Novel drugs under development for the treatment of respiratory diseases
Year: 2003