Hedgehog signalling crosstalks orchestrate human lung development

R. Belgacemi (Reims, France), S. Danopoulos (Los Angeles, United States of America), G. Deslée (Reims, France), V. Dormoy (Reims, France), D. Al Alam (Los Angeles, United States of America)

Source: Virtual Congress 2020 – Cellular stress in respiratory diseases
Session: Cellular stress in respiratory diseases
Session type: E-poster session
Number: 596
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Belgacemi (Reims, France), S. Danopoulos (Los Angeles, United States of America), G. Deslée (Reims, France), V. Dormoy (Reims, France), D. Al Alam (Los Angeles, United States of America). Hedgehog signalling crosstalks orchestrate human lung development. 596

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Wnt and TGF-beta signaling in lung development
Source: Lung Science Conference 2009 - Cell proliferation, Differentiation and Carcinogenesis
Year: 2009



Wnt signalling in lung repair and remodelling
Source: International Congress 2017 – Lung tissue repair and remodelling in chronic lung diseases: mechanisms and therapeutic approaches
Year: 2017


Involvement of Hedgehog pathway in airway cell differentiation
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018




BMP-Smad1 target gene Wnt inhibitory factor 1 (WIF1) coordinates BMP and Wnt signaling activities in regulating lung development in vivo
Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases
Year: 2010

Roles of Rho-Rock and Smad pathways in TGFβ1-mediated lung fibroblast differentiation
Source: Annual Congress 2008 - Regulatory mechanisms of cell activation, renewal and recruitment
Year: 2008

HMGA2 mediated epigenetic regulation of Gata6 controls epithelial WNT signaling during lung development
Source: International Congress 2017 – Molecular biology of normal and abnormal lung development
Year: 2017

YI02 - Activation of Wnt/beta-catenin signaling promotes lung epithelial repair in emphysema
Source: Lung Science Conference 2012 - Rebuilding a diseased lung: Repair and regeneration
Year: 2012

Genetic targeting of the pulmonary epithelium: the role of TGF-b and wnt signaling in ontogeny of specialized cell types
Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation
Year: 2009


Micro RNA-21 Targeting PI3K/PTEN/Akt signaling axis regulates multiple biological functions in human lung cancer
Source: International Congress 2018 – Lung cancer: from the bench to the bedside
Year: 2018


Targeting the Hippo signaling pathway to enhance ex vivo lung epithelial tissue regeneration and maturation
Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis
Year: 2019

WNT5A antagonizes canonical WNT/beta-catenin signaling in lung epithelial cells
Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation
Year: 2013

Activation of WNT co-receptor LRP5  is required for WNT and TGF-ß1 induced fibroblast activation
Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies
Year: 2020


Leptin activates the JAK/STAT signaling pathway in bronchial and alveolar epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 338s
Year: 2006

Signalling mechanisms that regulate lung inflammation in humans
Source: Annual Congress 2004 - Acquired somatic mutations in the pathogenesis of COPD
Year: 2004

Non-canonical WNT signaling is mediated by extracellular vesicles in pulmonary fibrosis
Source: ERS Lung Science Conference 2016
Year: 2016

The Hippo pathway effectors TAZ and YAP are sequentially required in lung development.
Source: International Congress 2019 – Molecular and experimental paediatric lung disease
Year: 2019



Hedgehog pathway activation is altered in COPD patients
Source: International Congress 2019 – Cellular responses and cell therapy in lung injury and repair
Year: 2019


Temporal analysis of the intracellular signaling pathways involved in Th17/Treg response in COPD development
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019