The role of eosinophils in airway hyperresponsiveness in diet-induced obese mice

G. Calco (Portland, United States of America), B. Proskocil (Portland, United States of America), D. Jacoby (Portland, United States of America), A. Fryer (Portland, United States of America), Z. Nie (Portland, United States of America)

Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma
Session: Novel mechanisms elucidated by translational studies of asthma
Session type: Poster Discussion
Number: 5201
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
G. Calco (Portland, United States of America), B. Proskocil (Portland, United States of America), D. Jacoby (Portland, United States of America), A. Fryer (Portland, United States of America), Z. Nie (Portland, United States of America). The role of eosinophils in airway hyperresponsiveness in diet-induced obese mice. 5201

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Oral presentation: ILC2 contribute to ozone-induced airway hyperresponsiveness in obese mice
Source: Lung Science Conference 2014 - Lung Inflammation and Immunity
Year: 2014



Different effects of cox-inhibition on airway inflammation and hyperresponsiveness in mice
Source: Eur Respir J 2007; 30: Suppl. 51, 713s
Year: 2007

The role of CCR5 in allergen-induced airway hyperresponsiveness and airway inflammation
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009

Development of IL-33-induced asthmatic airway inflammation in human IL-3/GM-CSF/IL-5-transgenic NOG mice
Source: International Congress 2017 – "Alarming" immunological patterns in asthma
Year: 2017


Study of role of insulin and insulin receptor in allergic airway inflammation of rats
Source: Eur Respir J 2005; 26: Suppl. 49, 587s
Year: 2005

MMP-9 deficiency reduces airway inflammation and hyperresponsiveness in a mouse model of asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 20s
Year: 2001

Effects of active and passive smoking on allergic airway inflammation and airway hyperresponsiveness in mice
Source: Eur Respir J 2002; 20: Suppl. 38, 310s
Year: 2002

Obesity enhances allergen-induced airway inflammation in a murine model of asthma
Source: International Congress 2019 – Modelling and monitoring of airway diseases
Year: 2019

CCL6 produced by eosinophils drives allergic airway inflammation in mice
Source: International Congress 2019 – Modelling and monitoring of airway diseases
Year: 2019

Airway allergy in pregnant mice: reduced Th2 responses but enhanced airway hyperresponsiveness
Source: Eur Respir J 2006; 28: Suppl. 50, 590s
Year: 2006

S-carboxymethylcysteine normalises airway responsiveness in sensitised and challenged mice
Source: Eur Respir J 2005; 26: 577-585
Year: 2005



Effects of OVA-induced allergic airway inflammation and remodeling in mice in three distinct asthma models
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Dissociation of the effects of a steroid on inflammation compared to airway hyperresponsiveness (AHR) in a model of asthma in conscious mice
Source: Eur Respir J 2001; 18: Suppl. 33, 30s
Year: 2001

5,6,7-Trihydroxy-4´-methoxy-flavanone from Baccharis retusa (asteraceae) attenuates allergen-induced airway inflammation and hyperresponsiveness in mice
Source: Annual Congress 2010 - Regulation of airway hyperresponsiveness and bronchodilators
Year: 2010

Deficiency of MMP-19 promotes allergen-induced eosinophil burden and airway responsiveness in mice
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007



A role for Th1 cells in airway remodeling and hyperreactivity in mice subjected to chronic allergen exposure
Source: Eur Respir J 2007; 30: Suppl. 51, 734s
Year: 2007

Effects of IL-4Rα blockade on lung inflammation and airway hyperresponsiveness using Mu317RAXMu, a murine surrogate for AMG 317, in a treatment model of cockroach allergen-induced asthma in mice
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008

VIP knockout mice show asthma-like airway hyper-reactivity, and inflammatory response to immunologic challenge
Source: Eur Respir J 2004; 24: Suppl. 48, 658s
Year: 2004

ILC2s in allergic airway inflammation
Source: International Congress 2014 – Highlights from the Lung Science Conference 2014
Year: 2014



Transgenic mice overexpressing IL-18 display increased IL-13 in the airways but no changes of the airway hyperresponsiveness in a murine model of late-phase asthma: evidence for a dual role of IL-18 on mucosal Th1/Th2 responses
Source: Eur Respir J 2002; 20: Suppl. 38, 1s
Year: 2002