Hepatotoxic reactions in rats after administration of component schemes of reserve Anti-TB drugs with different safety profile

A. Kazakov (Moscow, Russian Federation), G. Mozhokina (Moscow, Russian Federation), Y. Zyuzya (Moscow, Russian Federation), L. Petrova (Moscow, Russian Federation)

Source: International Congress 2019 – Tuberculosis: from basic science to patient care
Session: Tuberculosis: from basic science to patient care
Session type: Thematic Poster
Number: 4604
Disease area: Respiratory infections

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Kazakov (Moscow, Russian Federation), G. Mozhokina (Moscow, Russian Federation), Y. Zyuzya (Moscow, Russian Federation), L. Petrova (Moscow, Russian Federation). Hepatotoxic reactions in rats after administration of component schemes of reserve Anti-TB drugs with different safety profile. 4604

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Experimental justification choise to prevent hepatotoxic reactions to anti-TB drugs based on gene-phenotypic characteristics
Source: International Congress 2019 – Tuberculosis: diagnosis
Year: 2019

Evaluation of antituberculous drugs administration
Source: Eur Respir J 2002; 20: Suppl. 38, 547s
Year: 2002

Novel paradigm for inhaled therapies: simulation of drug pharmacokinetic behaviour and effect of disease
Source: Eur Respir J 2003; 22: Suppl. 45, 474s
Year: 2003

Comparison of efficacy and safety of fixed-dose combination regimen versus separate drugs for treatment of tuberculosis
Source: International Congress 2019 – Insights into paediatric bronchology
Year: 2019

Cardiotoxicity of a complex of anti-tuberculosis drugs with the inclusion of fluoroquinolones and bedaquiline in an experiment on rats
Source: Virtual Congress 2021 – Immunological and molecular characterisation of tuberculosis disease and infection
Year: 2021

Comparison of the pharmacokinetic, pharmacodynamic, and safety profiles of three different formulations of intravenous epoprostenol sodium
Source: Annual Congress 2012 - Pulmonary circulation: clinical PAH, registries and treatments
Year: 2012


The nephrotoxic effect assesment of tuberculostatic drugs therapy by urinary enzymes
Source: Eur Respir J 2004; 24: Suppl. 48, 654s
Year: 2004

Comparison of anti-tuberculosis regimens using fixed dose combination versus single drugs
Source: Annual Congress 2010 - Prognosis of tuberculosis
Year: 2010


Adverse drug reactions and outcomes of tuberculosis treatment using fixed-dose combination (FDC) regimen
Source: Annual Congress 2012 - Tuberculosis: clinical findings I
Year: 2012

The efficacy, safety and tolerability of the short 12-month pre-XDR-TB regimen regimen in Ukraine at the expense of using intravenous administration of anti-tuberculosis drugs during intensive phase
Source: International Congress 2017 – Paediatric TB: MDRTB (II)
Year: 2017

The efficacy, safety and tolerability of the short 12-month MDR-TB regimen in Ukraine at the expense of using intravenous administration of anti-tuberculosis drugs during intensive phase
Source: International Congress 2017 – Treatment of multi-drug-resistant tuberculosis (MDRTB): where are we now?
Year: 2017



Inhalations of ultra-low doses of alkylating drug for the treatment of steroid-dependant asthma: anti-inflammatory effect of therapy
Source: Eur Respir J 2001; 18: Suppl. 33, 266s
Year: 2001

Pharmacokinetics and drug susceptibility testing imply limited activity of current regimens for Mycobacterium avium complex disease
Source: Annual Congress 2012 - Non-tuberculous and tuberculous mycobacterial infections: from epidemiology to clinical findings
Year: 2012

Relative risks of HPA axis effects for commonly prescribed corticosteroid dose regimens
Source: Eur Respir J 2004; 24: Suppl. 48, 620s
Year: 2004

Fluticasone propionate/formoterol fumarate combination therapy has an efficacy and safety profile similar to that of its individual components administered concurrently in the treatment of asthma
Source: Annual Congress 2010 - Combination therapy in asthma and COPD
Year: 2010

Time to ban short-acting ß-agonists and use anti-inflammatory treatment as required to improve outcomes
Source: Virtual Congress 2021 – Wheezing illnesses along the life span
Year: 2021


Severe adverse effects of antitubercular drugs and patient management
Source: Annual Congress 2011 - Treatment of tuberculosis and adverse drug reactions
Year: 2011


Management of adverse drug events in TB therapy
Source: Eur Respir Mon 2012; 58: 167-193
Year: 2012


Real-life use of long-acting antimuscarinic agents following their approval for COPD treatment
Source: Eur Respir J 2015; 45: 260-262
Year: 2015


Retrial of identical agents in patients with toxic hepatitis caused by first line antituberculosis drugs
Source: Annual Congress 2010 - Adverse events of antituberculosis treatment and comorbidities
Year: 2010