GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
COX-1 driven biosynthesis of PGD2 during activation of human mast cells prevents formation of other prostanoids Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes Year: 2020
Bronchoconstriction induced by prostaglandin D2 (PGD2 ) in guinea pig lung is enhanced by selective COX-2 inhibition Source: Eur Respir J 2006; 28: Suppl. 50, 759s Year: 2006
Inhibition of eosinophil migration by montelukast, a cysteinyl leukotriene receptor antagonist, through down regulation of plasmin activity Source: Eur Respir J 2004; 24: Suppl. 48, 36s Year: 2004
Fevipiprant inhibits prostaglandin D2 mediated activation of group 2 innate lymphoid cells (ILC2s) Source: International Congress 2018 – Studies on the mechanisms underlying airway disease Year: 2018
Resolvin D1 attenuates lung inflammation in LPS induced-ALI partly through PPARγ/NF-κB pathway Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury Year: 2011
Prostaglandin D2 inhibits fibroblast migration Source: Eur Respir J 2002; 19: 684-689 Year: 2002
Generation and activation of myeloid derived suppressor cells using prostaglandin E2 and EP receptor agonists in vitro Source: International Congress 2019 – Advances in asthma pharmacology Year: 2019
Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 29s Year: 2004
Activation of E-prostanoid4 and E-prostanoid2 receptors inhibits TNF-α release from human alveolar macrophages Source: Eur Respir J 2007; 29: 986-994 Year: 2007
Liver-X-receptor agonists, but not dexamethasone, inhibit leukotriene production from human white blood cells pretreated with GM-CSF and activated with fMLP Source: Annual Congress 2007 - New treatments for asthma and COPD - experimental evidence Year: 2007
The pro-apoptotic effect of cysteinyl leukotriene receptor (CysLT-R) antagonist montelukast is mediated by CysLT-Rs expression on antigen-stimulated T cells Source: Eur Respir J 2003; 22: Suppl. 45, 100s Year: 2003
A novel protective role of prostaglandin D2 in antigen-induced bronchoconstriction Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Effects of zileuton on leukotriene formation in human blood cells and expression of enzymes in the biosynthetic pathway Source: Eur Respir J 2006; 28: Suppl. 50, 316s Year: 2006
NF-κB-dependent cytokine production is abolished by cyclopentenone prostaglandins in lung epithelial cells Source: Eur Respir J 2001; 18: Suppl. 33, 354s Year: 2001
Inhibition of LPS-induced neutrophil recruitment in the lungs correlates with modulation of neutrophil CD11b expression using the selective CXCR2 receptor antagonist SB-656933 Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
Prostaglandin E2 inhibits NLRP3 inflammasome activation through EP4 receptor and intracellular cAMP in human macrophages Source: International Congress 2015 – Mucosal immunology: what’s new in 2015 Year: 2015
Do leukotriene antagonists reduce eosinophil numbers in induced sputum from asthmatic patients as a consequence of increased apoptosis induction? Source: Eur Respir J 2002; 20: Suppl. 38, 584s Year: 2002
Antigen-induced formation of prostaglandin D2 in mouse asthma model Source: Eur Respir J 2005; 26: Suppl. 49, 578s Year: 2005
Synergistic suppression of human rhinovirus induced pro-inflammatory cytokines by B2 agonists and glucocorticoids Source: Annual Congress 2004 - Mechanisms and treatment of virus induced asthma exacerbations Year: 2004