Disease and cell type specific glucocorticoid receptor-isoform expression and re-synthesis in asthma

L. Zhou (Basel, Switzerland), L. Fang (Basel, Switzerland), M. Roth (Basel, Switzerland), M. Tamm (Basel, Switzerland), D. Stolz (Basel, Switzerland)

Source: International Congress 2019 – Airway inflammation: pharmacological mechanisms and novel targets
Session: Airway inflammation: pharmacological mechanisms and novel targets
Session type: Thematic Poster
Number: 4212
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
L. Zhou (Basel, Switzerland), L. Fang (Basel, Switzerland), M. Roth (Basel, Switzerland), M. Tamm (Basel, Switzerland), D. Stolz (Basel, Switzerland). Disease and cell type specific glucocorticoid receptor-isoform expression and re-synthesis in asthma. 4212

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IL-25 receptor expression on basophil membrane is related to phenotype and severity of asthma
Source: International Congress 2015 – Asthma and lung immunology
Year: 2015

Glucocorticoid potency correlates with transcriptional induction of a glucocorticoid regulated gene in human monocytes
Source: Eur Respir J 2005; 26: Suppl. 49, 369s
Year: 2005

Inhibition of inflammatory gene expression by dexamethasone partly depends on the phosphatase, MKP-1 (DUSP1)
Source: Annual Congress 2013 –Novel drugs and biomarkers in respiratory medicine
Year: 2013

Targeted silencing of master transcription factor SPDEF to reduce mucus production in airway diseases by epigenetic editing
Source: International Congress 2015 – Advances in the future treatment of COPD
Year: 2015



Altered P2 receptor expression profile in sputum cells of patients with COPD
Source: International Congress 2014 – Monitoring COPD with different biomarkers
Year: 2014

Aerobic training reverses the inhibition in the expression of glucocorticoid receptors and decreases the Th2 allergic inflammation in asthma model
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


Asthma and diabetes: Possible markers of their co-existence. The possible role of transcription factors GATA-3 and T-bet and negative regulator of transcription SOCS1 in the worsening of asthma
Source: International Congress 2015 – Translational research in respiratory care: new findings
Year: 2015

Disease and stimulus specific pro-inflammatory cytokine secretion by human fibroblast of asthma patients
Source: Annual Congress 2011 - Immunology and cell biology of asthma and COPD
Year: 2011

Egr-1 regulates muc5ac expression through activator protein-1 (AP-1) in chronic airway inflammation diseases
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015


Evaluation of mRNA expression profiling of NF-?B mediated signaling in COPD patients.
Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies
Year: 2020

The dynamic change of IL-25 and its receptor expression during allergen challenge in asthmatic subjects
Source: International Congress 2015 – Novel mechanisms and treatments in allergy and asthma
Year: 2015



Cell type and disease specific expression of GPR68 in the human lung
Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes
Year: 2020


Expression of estrogen receptors and estrogen metabolism genes in lungs of COPD patients
Source: International Congress 2015 – Inflammation and remodelling in lung disease
Year: 2015

Sputum cell mRNA transcripts demonstrate alteration of endothelin metabolism in severe asthma and COPD
Source: Annual Congress 2013 –New drugs in respiratory medicine
Year: 2013

Altered expression of histamine receptor 4 and MAPK kinase in childhood asthma
Source: International Congress 2015 – More paediatric asthma and allergy
Year: 2015

The role of suppressor of cytokine signalling 1 (SOCS1) in virus-induced asthma exacerbations
Source: International Congress 2016 – Viral infections in different respiratory conditions: from the bedside to the lab
Year: 2016


Corticosteroid effects on cell signalling
Source: Eur Respir J 2006; 27: 413-426
Year: 2006



Bronchial thermoplasty may increase steroid sensitivity by upregulating the expression of the glucocorticoid receptor
Source: Virtual Congress 2020 – Asthma pharmacology: clinical trials and mechanistic insights
Year: 2020



Interleukin-12 receptor mRNA expression and corticosteroid depended eosinophil apoptosis in asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 223s
Year: 2003

Cell differentiation controls the cellular distribution of the glucocorticoid receptor
Source: Eur Respir J 2003; 22: Suppl. 45, 224s
Year: 2003