Source: Eur Respir Rev, 28 (154) 190092; 10.1183/16000617.0092-2019
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
Timothy S.C. Hinks, Ryan D. Hoyle, Erwin W. Gelfand. CD8⁺ Tc2 cells: underappreciated contributors to severe asthma. Eur Respir Rev, 28 (154) 190092; 10.1183/16000617.0092-2019

Member's Comments

No comment yet.

Related content which might interest you: Type-2 CD8+ T lymphocytes responsive to PGD2/LTE4 in severe eosinophilic asthma Source: International Congress 2018 – Advanced profiling of immune cells in chronic lung diseases Year: 2018 IL-10-producing CD4+ T cells are essential for the development of airway hyperresponsiveness Source: Annual Congress 2004 - Modulation of the allergic response in animal models Year: 2004 LATE-BREAKING ABSTRACT: Increased cytotoxic T cells, CX3CR1+, γδ and IL17+ T cells in severe asthma during exacerbation Source: Annual Congress 2012 - Late breaking results: Asthma from phenotyping to emerging new treatments Year: 2012 Inflammatory process of CD8+ CD28- T cells in induced sputum from asthmatic patients Source: Eur Respir J 2005; 26: Suppl. 49, 25s Year: 2005 Characteristics of fatal asthma: CD8 positive T cells producing IFN-γ and IL-18 were recruited into small airways in fatal asthma Source: Annual Congress 2009 - COPD and asthma - from the cell to the clinic Year: 2009 The declined CD4+ CD25+Treg cells in patients with moderate to severe asthma associated with over-expressed Th2 response Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms Year: 2012 Possible involvement of CD8+ cells and their subpopulations in COPD exacerbations Source: Eur Respir J 2002; 20: Suppl. 38, 505s Year: 2002 Increase of both blood CXCR3+ and CCR4+ helper T cells associated with severity of asthma Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma Year: 2005 CD39/CD73 and the imbalance of Th17 and Tregs (regulatory T cells) in allergic asthma Source: Annual Congress 2013 –Studies of asthma in man Year: 2013 CD4+CD25+ T lymphocytes in patients with COPD Source: Eur Respir J 2004; 24: Suppl. 48, 319s Year: 2004 Late-breaking abstract: Role of IL-13-producing BLT1-positive CD8 T cells in asthmatic airway obstruction Source: Annual Congress 2011 - Cell biology of lung disease Year: 2011 Reduced numbers of circulating CD4+CD25highFOXP3+ regulatory T cells in patients with allergic asthma Source: Annual Congress 2008 - Understanding airway inflammation Year: 2008 CD4+ and CD8+ T lymphocytes display a Th2/Tc2 cytokine profile in COPD Source: Eur Respir J 2004; 24: Suppl. 48, 319s Year: 2004 Enhanced expression of IL-18 and increased CD8+ T cells and eosinophils in the airways of asthma death Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation Year: 2010 Increased levels of CD4+CD25high and CD4+FoxP3+ T-regulatory cells (Tregs) in patients with different severity of bronchial asthma (BA) Source: Annual Congress 2011 - Immunology and cell biology of asthma and COPD Year: 2011 High percentage of CD8+ effector T lymphocytes in patients with chronic obstructive pulmonary disease Source: Eur Respir J 2002; 20: Suppl. 38, 591s Year: 2002 Omalizumab enhances the percentage of GARP cells in both regulatory and terminally differentiated effector Th cells in severe allergic asthmatics Source: International Congress 2018 – Novel immunology-based therapies in asthma and COPD Year: 2018 Evidence for cell mediated immune dysfunction in the COPD lung: The role of cytotoxic CD4+ T cells Source: International Congress 2015 – Viral infections: basic research and clinical perspective Year: 2015 Decreased regulation of lung CD8+ T cells by virally-infected macrophages in COPD: Role of PD1/PDL1 axis Source: International Congress 2015 – Advances from translational research in respiratory infections Year: 2015