Search all ERS
Interstitial Lung Diseases
Respiratory Critical Care
Paediatric Respiratory Diseases
Pulmonary Vascular Diseases
Sleep and Breathing Disorders
ERJ Open Research
European Lung White Book
All ERS guidelines
Global Lung Function Initiative
Reference Database of Respiratory Sounds
Radiology Image Challenge
Brief tobacco interventions
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
Malcolm R. Starkey, Maximilian W. Plank, Paolo Casolari, Alberto Papi, Stelios Pavlidis, Yike Guo, Guy J.M. Cameron, Tatt Jhong Haw, Anthony Tam, Ma'en Obiedat, Chantal Donovan, Nicole G. Hansbro, Duc H. Nguyen, Prema Mono Nair, Richard Y. Kim, Jay C. Horvat, Gerard E. Kaiko, Scott K. Durum, Peter A. Wark, Don D. Sin, Gaetano Caramori, Ian M. Adcock, Paul S. Foster, Philip M. Hansbro
Eur Respir J, 54 (1) 1800174; 10.1183/13993003.00174-2018
to grade this presentation.
Share or cite this content
Citations should be made in the following way:
Malcolm R. Starkey, Maximilian W. Plank, Paolo Casolari, Alberto Papi, Stelios Pavlidis, Yike Guo, Guy J.M. Cameron, Tatt Jhong Haw, Anthony Tam, Ma'en Obiedat, Chantal Donovan, Nicole G. Hansbro, Duc H. Nguyen, Prema Mono Nair, Richard Y. Kim, Jay C. Horvat, Gerard E. Kaiko, Scott K. Durum, Peter A. Wark, Don D. Sin, Gaetano Caramori, Ian M. Adcock, Paul S. Foster, Philip M. Hansbro. IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis. Eur Respir J, 54 (1) 1800174; 10.1183/13993003.00174-2018
to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
No comment yet.
to comment this presentation.
Related content which might interest you:
Managing COVID-19 illness: chest radiographs support defining both prognosis and follow up.
A 51-year-old man with 10-day history of cough, fever, odynodysphagie, dyspnea and fatigue
A 21-year-old woman with progressive dyspnea since 1 year
Related content which might interest you:
The roles of Th2 cytokines and their signaling pathways in the pathogenesis of non-eosinophilic asthma enhanced by dsRNA
Source: Annual Congress 2006 - Immunological mechanisms in cell recruitment to the lungs
The involvement of thrombospondin-1 in COPD pathogenesis through IL-8 production
Source: Annual Congress 2013 –COPD: experimental biology
A decreased expression of leptin receptor may contribute to the pathogenesis of the allergic rhinitis
Source: Annual Congress 2010 - Asthma: clinical aspects and treatment
The role of lipoxin A
and its receptor in pathogenesis of inflammatory lung diseases
Source: Annual Congress 2010 - Novel markers of lung injury
IL-33 blockade impacts mediators of persistence and exacerbation of chronic airway inflammation.
Source: International Congress 2018 – Novel drug targets for asthma and COPD
Anti-Th2 cytokines inhibit progression in a murine model of childhood asthma
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
IL-33 may augment the effect of rhinovirus HRV16 on the inflammatory activity of human lung vascular endothelium – possible implication for asthma exacerbations.
Source: Virtual Congress 2021 – New insight into the immunology of allergies, asthma and COPD: from mouse to man
PAH and inflammation: its role in pathogenesis - is it of value to modulate it?
Source: Annual Congress 2005 - Challenges in the biological understanding of pulmonary arterial hypertension
The role of IL-10 receptors in aberrant homeostatic control of TNF-α in idiopathic pulmonary fibrosis (IPF)
Source: Eur Respir J 2002; 20: Suppl. 38, 599s
GM-CSF is a key pathogenic mediator in experimental COPD
Source: Eur Respir J 2005; 26: Suppl. 49, 13s
Human rhinovirus 16 infection of human macrophages significantly impairs their phagocytic and regulatory functions: implications in understanding chronic inflammatory lung disease
Source: International Congress 2017 – New Mechanistic Findings in COPD
Evidence for differential roles of Th1 and Th17 cytokines in the pathogenesis of COPD
Source: Annual Congress 2010 - Pathology and immunology of COPD
Carbocisteine in vivo reduces circulating miR-21 and IL-8 in exacerbated COPD patients
Source: International Congress 2019 – COPD clinical trials: inhaled and oral therapies
The role of the COPD susceptibility gene FAM13A in barrier function and pro-inflammatory responses of human airway epithelial cells
Source: ERS Lung Science Conference 2020
IL-33 augments rhinovirus-induced type 2 immune responses in asthma via selective upregulation of one chain of the IL-33 receptor.
Source: International Congress 2017 – "Alarming" immunological patterns in asthma
IL-17A is elevated in patients with COPD and contributes to airway remodeling by acting on fibroblasts
Source: International Congress 2016 – What's new in biomarker analysis?
RAGE-dependent VCAM-1 expression in the pulmonary endothelium mediates IL-33 induced asthma pathogenesis
Source: International Congress 2017 – Therapeutic approaches in lung disease
Transgenic mice overexpressing IL-18 display increased IL-13 in the airways but no changes of the airway hyperresponsiveness in a murine model of late-phase asthma: evidence for a dual role of IL-18 on mucosal Th1/Th2 responses
Source: Eur Respir J 2002; 20: Suppl. 38, 1s
Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations
Source: Eur Respir J, 50 (4) 1602434; 10.1183/13993003.02434-2016
Interferon-gamma (IFN-γ) alters the expression of IP-10 and IL-18 in human aveolar epithelial cells type II. Possible role in the reinforcement of Th1-dominated lung inflammation
Source: Eur Respir J 2001; 18: Suppl. 33, 521s